(Q28271724)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

RSK phosphorylates SOS1 creating 14-3-3-docking sites and negatively regulating MAPK activation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

0 references

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Audrey Carrière

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Philippe P. Roux

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

author name string

Mujeeburahiman Cheerathodi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Xiaocui Zhang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Geneviève Lavoie

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

John Rush

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Bryan A Ballif

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

language of work or name

English

0 references

publication date

1 October 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

volume

447

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

page(s)

159-166

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json

Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases

8 February 2020

cites work

1 reference

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RPS6KA2, a putative tumour suppressor gene at 6q27 in sporadic epithelial ovarian cancer

20 March 2017

1 reference

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Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

20 March 2017

1 reference

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WebLogo: A Sequence Logo Generator

20 March 2017

1 reference

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Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs

20 March 2017

1 reference

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Rsk1 mediates a MEK-MAP kinase cell survival signal

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Phosphorylation and regulation of Raf by Akt (protein kinase B)

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Identification of the mitogen-activated protein kinase phosphorylation sites on human Sos1 that regulate interaction with Grb2

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

C-TAK1 regulates Ras signaling by phosphorylating the MAPK scaffold, KSR1

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

The structural basis for 14-3-3:phosphopeptide binding specificity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Ras oncogenes: split personalities

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Hyperactive Ras in developmental disorders and cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Strong negative feedback from Erk to Raf confers robustness to MAPK signalling.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Absolute quantification of protein and post-translational modification abundance with stable isotope-labeled synthetic peptides

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Impact of feedback phosphorylation and Raf heterodimerization on normal and mutant B-Raf signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Non-redundancy within the RAS oncogene family: insights into mutational disparities in cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Regulation of replicative and stress-induced senescence by RSK4, which is down-regulated in human tumors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Signaling dynamics of the KSR1 scaffold complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Modelling oncogenic Ras/Raf signalling in the mouse.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

The RSK factors of activating the Ras/MAPK signaling cascade

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

The RAS/MAPK syndromes: novel roles of the RAS pathway in human genetic disorders

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

MAPK signal specificity: the right place at the right time

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

The tumor suppressor DAP kinase is a target of RSK-mediated survival signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Graded mitogen-activated protein kinase activity precedes switch-like c-Fos induction in mammalian cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Regulation of Raf-1 by direct feedback phosphorylation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

A network of immediate early gene products propagates subtle differences in mitogen-activated protein kinase signal amplitude and duration.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Induction of senescence by oncogenic Ras.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Altered extracellular signal-regulated kinase signaling and glycogen metabolism in skeletal muscle from p90 ribosomal S6 kinase 2 knockout mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Raf-1 kinase and exoenzyme S interact with 14-3-3zeta through a common site involving lysine 49.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Evidence for two catalytically active kinase domains in pp90rsk

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198020

Altered ERK/MAPK signaling in the hippocampus of the mrsk2_KO mouse model of Coffin-Lowry syndrome.

2 June 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120938

Identification of 14-3-3epsilon substrates from embryonic murine brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120938

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120938

Paving the way for targeting RSK in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120938

EGF induced SOS phosphorylation in PC12 cells involves P90 RSK-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120938

14-3-3 proteins: a number of functions for a numbered protein

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22827337

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/22827337

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Comparison of the specificities of p70 S6 kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 S6 kinase: the N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide phosphorylation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22827337

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1042/BJ20120938

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

22827337

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22827337%20AND%20SRC:MED&resulttype=core&format=json