(Q28272531)

12 December 2020

Characterization of cell cycle checkpoint responses after ionizing radiation in Nijmegen breakage syndrome cells

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12 December 2020

Mutations in the MRE11, RAD50, XRS2, and MRE2 genes alter chromatin configuration at meiotic DNA double-stranded break sites in premeiotic and meiotic cells

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12 December 2020

Human MRE11 is inactivated in mismatch repair-deficient cancers

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12 December 2020

NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres

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12 December 2020

A role for Saccharomyces cerevisiae histone H2A in DNA repair.

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12 December 2020

Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation

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12 December 2020

Werner syndrome protein, the MRE11 complex and ATR: menage-à-trois in guarding genome stability during DNA replication?

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12 December 2020

Expression pattern of the Nijmegen breakage syndrome gene, Nbs1, during murine development

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12 December 2020

NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain

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12 December 2020

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

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12 December 2020

Nijmegen breakage syndrome disease protein and MRE11 at PML nuclear bodies and meiotic telomeres

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12 December 2020

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

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12 December 2020

Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

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12 December 2020

Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination.

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12 December 2020

Recruitment of NBS1 into PML oncogenic domains via interaction with SP100 protein

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12 December 2020

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

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12 December 2020

The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

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12 December 2020

Functional analysis of FHA and BRCT domains of NBS1 in chromatin association and DNA damage responses

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12 December 2020

Assembly of functional ALT-associated promyelocytic leukemia bodies requires Nijmegen Breakage Syndrome 1

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12 December 2020

Regulation of Mre11/Rad50 by Nbs1: effects on nucleotide-dependent DNA binding and association with ataxia-telangiectasia-like disorder mutant complexes.

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12 December 2020

MDC1 is required for the intra-S-phase DNA damage checkpoint

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12 December 2020

Nijmegen breakage syndrome cells fail to induce the p53-mediated DNA damage response following exposure to ionizing radiation

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12 December 2020

In situ visualization of DNA double-strand break repair in human fibroblasts

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12 December 2020

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

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12 December 2020

Molecular characterization of the Schizosaccharomyces pombe nbs1+ gene involved in DNA repair and telomere maintenance

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12 December 2020

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

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12 December 2020

Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart

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12 December 2020

Radiation induction of p53 in cells from Nijmegen breakage syndrome is defective but not similar to ataxia-telangiectasia

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12 December 2020

Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

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12 December 2020

The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms

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12 December 2020

Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

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12 December 2020

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

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12 December 2020

The Mre11 complex: at the crossroads of dna repair and checkpoint signalling

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12 December 2020

Normal V(D)J recombination in cells from patients with Nijmegen breakage syndrome

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12 December 2020

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

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12 December 2020

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

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12 December 2020

Impaired p53-mediated DNA damage response, cell-cycle disturbance and chromosome aberrations in Nijmegen breakage syndrome lymphoblastoid cell lines.

1 reference

12 December 2020

Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants

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12 December 2020

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

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12 December 2020

The Rad51 paralog Rad51B promotes homologous recombinational repair

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12 December 2020

The many interfaces of Mre11

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12 December 2020

Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair

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12 December 2020

The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways

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12 December 2020

Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest

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12 December 2020

Positional cloning and functional analysis of the gene responsible for Nijmegen breakage syndrome, NBS1.

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12 December 2020

Human Rad50/Mre11 is a flexible complex that can tether DNA ends

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12 December 2020

ATM phosphorylates histone H2AX in response to DNA double-strand breaks

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12 December 2020

Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit

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12 December 2020

A murine model of Nijmegen breakage syndrome

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12 December 2020

DNA damage-dependent nuclear dynamics of the Mre11 complex

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12 December 2020

The Mre11 complex is required for ATM activation and the G2/M checkpoint

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12 December 2020

The Nijmegen breakage syndrome protein is essential for Mre11 phosphorylation upon DNA damage

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12 December 2020

Expression of full-length NBS1 protein restores normal radiation responses in cells from Nijmegen breakage syndrome patients.

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12 December 2020

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

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12 December 2020

The plant Rad50-Mre11 protein complex

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12 December 2020

Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

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12 December 2020

Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells

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12 December 2020

Chk2 activation dependence on Nbs1 after DNA damage

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12 December 2020

Genomic instability in mice lacking histone H2AX

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12 December 2020

Mre11 and Rad50 from Pyrococcus furiosus: cloning and biochemical characterization reveal an evolutionarily conserved multiprotein machine

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12 December 2020

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

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12 December 2020

Decreased immunoglobulin class switching in Nijmegen Breakage syndrome due to the DNA repair defect.

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12 December 2020

Radiosensitivity in ataxia-telangiectasia: a new explanation

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12 December 2020

The forkhead-associated domain of NBS1 is essential for nuclear foci formation after irradiation but not essential for hRAD50[middle dot]hMRE11[middle dot]NBS1 complex DNA repair activity

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12 December 2020

MDC1 is a mediator of the mammalian DNA damage checkpoint

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12 December 2020

SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint

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12 December 2020

A 50-bp insertion from intron 2 between exons 2 and 3 of NBS1 may be a spliced variant.

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12 December 2020

Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body

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12 December 2020

Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells

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12 December 2020

PML NBs associate with the hMre11 complex and p53 at sites of irradiation induced DNA damage

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12 December 2020

Linkage between Werner syndrome protein and the Mre11 complex via Nbs1.

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12 December 2020

Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

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12 December 2020

Distinct functional domains of nibrin mediate Mre11 binding, focus formation, and nuclear localization

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12 December 2020