(Q28276987)

Gene Ontology release 2020-05-02

W Xu

2

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author name string

D Kimelman

series ordinal

3

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language of work or name

English

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publication date

4 December 2006

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published in

Oncogene

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volume

25

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page(s)

7482-91

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issue

57

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cites work

Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway

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https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Casein kinase Iepsilon modulates the signaling specificities of dishevelled

21 April 2017

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PR72, a novel regulator of Wnt signaling required for Naked cuticle function

21 April 2017

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PR130 is a modulator of the Wnt-signaling cascade that counters repression of the antagonist Naked cuticle

21 April 2017

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Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex

21 April 2017

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Interaction among GSK-3, GBP, axin, and APC in Xenopus axis specification

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

The crystal structure of the beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT

21 April 2017

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Crystal structure of a beta-catenin/Tcf complex

21 April 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation

21 April 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Three-dimensional structure of the armadillo repeat region of beta-catenin

21 April 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1210055

The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Interaction of dishevelled and Xenopus axin-related protein is required for wnt signal transduction

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway

21 April 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1.

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

21 April 2017

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Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

21 April 2017

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Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein

21 April 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1210055

The third 20 amino acid repeat is the tightest binding site of APC for beta-catenin

21 April 2017

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The Wnt signaling pathway in development and disease

21 April 2017

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Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

21 April 2017

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Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses

21 April 2017

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Axin-dependent phosphorylation of the adenomatous polyposis coli protein mediated by casein kinase 1epsilon

21 April 2017

1 reference

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Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Structural basis of the Axin-adenomatous polyposis coli interaction

21 April 2017

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A mechanism for Wnt coreceptor activation

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Differences between the interaction of beta-catenin with non-phosphorylated and single-mimicked phosphorylated 20-amino acid residue repeats of the APC protein

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Frat is dispensable for canonical Wnt signaling in mammals

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Runnin' with the Dvl: proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Crystal structure of a beta-catenin/APC complex reveals a critical role for APC phosphorylation in APC function

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210055

Wnt signalling in stem cells and cancer

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

21 April 2017

The renaissance of GSK3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

WNT and beta-catenin signalling: diseases and therapies

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Drosophila Twins regulates Armadillo levels in response to Wg/Wnt signal.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

A role of Dishevelled in relocating Axin to the plasma membrane during wingless signaling.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Kinase cogs go forward and reverse in the Wnt signaling machine.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Glycogen synthase kinase-3 beta mutagenesis identifies a common binding domain for GBP and Axin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Regulation of glycogen synthase kinase 3beta and downstream Wnt signaling by axin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Trimeric G protein-dependent frizzled signaling in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Regulation of Wnt signaling by protein-protein interaction and post-translational modifications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

G protein signaling from activated rat frizzled-1 to the beta-catenin-Lef-Tcf pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Biochemical characterization of the Drosophila wingless signaling pathway based on RNA interference

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Relays at the membrane

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Subcellular localization and signaling properties of dishevelled in developing vertebrate embryos.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

A positive role for the PP2A catalytic subunit in Wnt signal transduction.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Basic region of residues 228-231 of protein kinase CK1alpha is involved in its interaction with axin: binding to axin does not affect the kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Casein kinase I phosphorylates the Armadillo protein and induces its degradation in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

PP2A:B56ϵ is required for Wnt/β-catenin signaling during embryonic development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Adenomatous polyposis coli (APC) differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021

Suppression of glycogen synthase kinase activity is not sufficient for leukemia enhancer factor-1 activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210055

7 January 2021