(Q28277255)

5

0 references

David Haddleton

object named as

David M Haddleton

4

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author name string

Sinéad M Ryan

1

0 references

Xuexuan Wang

Expert Opinion on Drug Delivery

3

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language of work or name

English

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publication date

April 2008

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published in

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volume

5

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issue

4

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page(s)

371-83

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cites work

PEGylation, successful approach to drug delivery

1 reference

https://api.crossref.org/works/10.1517/17425247.5.4.371

Peptide and protein PEGylation: a review of problems and solutions

20 April 2017

2 references

https://api.crossref.org/works/10.1517/17425247.5.4.371

20 April 2017

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Pegaspargase: a review of clinical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/17425247.5.4.371

Peptides as tools and drugs for immunotherapies

20 April 2017

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Chitosan-PEG nanocapsules as new carriers for oral peptide delivery. Effect of chitosan pegylation degree

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

PEGylated bioactive molecules in biodegradable polymer microparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Size comparison between proteins PEGylated with branched and linear poly(ethylene glycol) molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Rational design of a potent, long-lasting form of interferon: a 40 kDa branched polyethylene glycol-conjugated interferon alpha-2a for the treatment of hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

PEG-modified protamine with improved pharmacological/pharmaceutical properties as a potential protamine substitute: synthesis and in vitro evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Improving the therapeutic efficacy of peptides and proteins: a role for polysialic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Chemistry for peptide and protein PEGylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

PEGylated proteins: evaluation of their safety in the absence of definitive metabolism studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Pharmacokinetic and biodistribution properties of poly(ethylene glycol)–protein conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Once-per-cycle pegfilgrastim (Neulasta) for the management of chemotherapy-induced neutropenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Pegylation of interferon alfa: structural and pharmacokinetic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Disulfide bridge based PEGylation of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Site-specific PEGylation of protein disulfide bonds using a three-carbon bridge

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Site-specific PEGylation of native disulfide bonds in therapeutic proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

A highly stable polyethylene glycol-conjugated human single-chain antibody neutralizing granulocyte-macrophage colony stimulating factor at low nanomolar concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Linear and branched bicin linkers for releasable PEGylation of macromolecules: controlled release in vivo and in vitro from mono- and multi-PEGylated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Phase I evaluation of a 40-kDa branched-chain long-acting pegylated IFN-alpha-2a with and without cytarabine in patients with chronic myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Therapeutic proteins: a comparison of chemical and biological properties of uricase conjugated to linear or branched poly(ethylene glycol) and poly(N-acryloylmorpholine).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Design and synthesis of N-maleimido-functionalized hydrophilic polymers via copper-mediated living radical polymerization: a suitable alternative to PEGylation chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Synthesis of novel polyampholyte comb-type copolymers consisting of a poly(L-lysine) backbone and hyaluronic acid side chains for a DNA carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Releasable PEGylation of proteins with customized linkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Sustained release of protein from poly(ethylene glycol) incorporated amphiphilic comb like polymers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

In situ preparation of protein-"smart" polymer conjugates with retention of bioactivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Streptavidin as a macroinitiator for polymerization: in situ protein-polymer conjugate formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Barriers to gene delivery using synthetic vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

21 January 2018

Pfizer dumps Exubera.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

The AIR inhaled insulin system: system components and pharmacokinetic/glucodynamic data

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

AIR Inhaled Insulin System: a novel insulin-delivery system for patients with diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

21 January 2018

Inhaled insulin: Exubera

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Clinical pharmacokinetics and pharmacodynamics of inhaled insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Evaluation of novel particles as pulmonary delivery systems for insulin in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Effect of PEGylation on the stability of liposomes during nebulisation and in lung surfactant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

In vitro assessment of transferrin-conjugated liposomes as drug delivery systems for inhalation therapy of lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Oral delivery of salmon calcitonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

The bioavailability of intranasal salmon calcitonin in healthy volunteers with and without a permeation enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

High-yield production of biologically active mono-PEGylated salmon calcitonin by site-specific PEGylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

A New Class of Polymers: Starburst-Dendritic Macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Dendrimers in biomedical applications--reflections on the field

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Stealth dendrimers for antiarrhythmic quinidine delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Macromolecular MRI contrast agents with small dendrimers: pharmacokinetic differences between sizes and cores

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Delivery of antisense oligonucleotides using cholesterol-modified sense dendrimers and cationic lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Intracellular delivery of oligonucleotide conjugates and dendrimer complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Tat-conjugated PAMAM dendrimers as delivery agents for antisense and siRNA oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Dendrimer/DNA complexes encapsulated in a water soluble polymer and supported on fast degrading star poly(DL-lactide) for localized gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Efficient gene delivery targeted to the brain using a transferrin-conjugated polyethyleneglycol-modified polyamidoamine dendrimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Surface acetylation of polyamidoamine (PAMAM) dendrimers decreases cytotoxicity while maintaining membrane permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

A PEGylated dendritic nanoparticulate carrier of fluorouracil

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Molecular engineering of dendritic polymers and their application as drug and gene delivery systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Nanoparticles in drug delivery and environmental exposure: same size, same risks?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Lipid vesicles for skin delivery of drugs: reviewing three decades of research.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Liposome-nanogel structures for future pharmaceutical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

New generation of liposomal drugs for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Functional polymeric nanoparticles: an efficient and promising tool for active delivery of bioactives

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Endocytosis of liposomes and intracellular fate of encapsulated molecules: encounter with a low pH compartment after internalization in coated vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Effects of ammonium chloride and chloroquine on endocytic uptake of liposomes by Kupffer cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

RNAi therapeutics: principles, prospects and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Cationic lipids, lipoplexes and intracellular delivery of genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Monomolecular assembly of siRNA and poly(ethylene glycol)-peptide copolymers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Chondroosseous dysplasia in severe combined immunodeficiency due to adenosine deaminase deficiency (chondroosseous dysplasia in ADA deficiency scid)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Water-soluble polymer conjugates of ZnPP for photodynamic tumor therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Poly(ethylene glycol) prodrugs of the CDK inhibitor, alsterpaullone (NSC 705701): synthesis and pharmacokinetic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Development and pharmacokinetics and pharmacodynamics of pegylated interferon alfa-2a (40 kD).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Treating cancer with PEG Intron: pharmacokinetic profile and dosing guidelines for an improved interferon-alpha-2b formulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

The design and development of pegfilgrastim (PEG-rmetHuG-CSF, Neulasta).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Pegaptanib sodium for the treatment of neovascular age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Metal-Catalyzed Living Radical Polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Design of Comb-Type Polyamine Copolymers for a Novel pH-Sensitive DNA Carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371

Fluorescently tagged polymer bioconjugates from protein derived macroinitiators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.5.4.371