(Q28277560)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16231052%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

review article

1 reference

title

Gutless adenovirus: last-generation adenovirus for gene therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16231052%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16231052%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Miguel Chillon

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16231052%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

author name string

Alba R

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16231052%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

language of work or name

English

0 references

publication date

1 October 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16231052%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16231052%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

volume

12 Suppl 1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16231052%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

page(s)

S18-27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16231052%20AND%20SRC:MED&resulttype=core&format=json

Production of first generation adenovirus vectors: a review

8 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Characteristics of a human cell line transformed by DNA from human adenovirus type 5

21 January 2018

1 reference

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Characterization of 911: a new helper cell line for the titration and propagation of early region 1-deleted adenoviral vectors.

21 January 2018

1 reference

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Efficient transformation of primary human amniocytes by E1 functions of Ad5: generation of new cell lines for adenoviral vector production

21 January 2018

1 reference

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New helper cells and matched early region 1-deleted adenovirus vectors prevent generation of replication-competent adenoviruses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Application of an immunoperoxidase monolayer assay for the detection of arboviral antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Variables affecting in vivo performance of high-capacity adenovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Optimization of the helper-dependent adenovirus system for production and potency in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Improved system for helper-dependent adenoviral vector production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Replication and packaging of helper-dependent adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Autoregulation of 2 micron circle gene expression provides a model for maintenance of stable plasmid copy levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Development of a FLP/frt system for generating helper-dependent adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

A phage integrase directs efficient site-specific integration in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Development of a size-restricted pIX-deleted helper virus for amplification of helper-dependent adenovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

An HSV amplicon-based helper system for helper-dependent adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

A novel system for the production of fully deleted adenovirus vectors that does not require helper adenovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Growth of 293 cells in suspension culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Optimization of the generation and propagation of gutless adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Immune responses against adenoviral vectors and their transgene products: a review of strategies for evasion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

The role of capsid-endothelial interactions in the innate immune response to adenovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Immune response to recombinant adenovirus in humans: capsid components from viral input are targets for vector-specific cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Lymphocyte responses and cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Macrophage depletion increases the safety, efficacy and persistence of adenovirus-mediated gene transfer in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Gene Therapy for Hemophilia B: Host Immunosuppression Prolongs the Therapeutic Effect of Adenovirus-Mediated Factor IX Expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Nonspecific inflammation inhibits adenovirus-mediated pulmonary gene transfer and expression independent of specific acquired immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Anti-T cell receptor monoclonal antibody prolongs transgene expression following adenovirus-mediated in vivo gene transfer to mouse synovium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Transient immunomodulation with anti-CD40 ligand antibody and CTLA4Ig enhances persistence and secondary adenovirus-mediated gene transfer into mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Effects of macrophage depletion and anti-CD40 ligand on transgene expression and redosing with recombinant adenovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Oral tolerization to adenoviral proteins permits repeated adenovirus-mediated gene therapy in rats with pre-existing immunity to adenoviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

A simian replication-defective adenoviral recombinant vaccine to HIV-1 gag.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Canine adenovirus vectors: an alternative for adenovirus-mediated gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Adenovirus complexed with polyethylene glycol and cationic lipid is shielded from neutralizing antibodies in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

"Stealth" adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

PEGylation of E1-deleted adenovirus vectors allows significant gene expression on readministration to liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

FK506 immunosuppression to control the immune reactions triggered by first-generation adenovirus-mediated gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

DNA from both high-capacity and first-generation adenoviral vectors remains intact in skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Prolonged expression and effective readministration of erythropoietin delivered with a fully deleted adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Helper-dependent adenoviral vectors efficiently express transgenes in human dendritic cells but still stimulate antiviral immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Helper-dependent adenovirus vectors elicit intact innate but attenuated adaptive host immune responses in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Factors influencing therapeutic efficacy and the host immune response to helper-dependent adenoviral gene therapy in hemophilia A mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

CAR chasing: canine adenovirus vectors-all bite and no bark?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for ch

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Preexisting antiadenoviral immunity is not a barrier to efficient and stable transduction of the brain, mediated by novel high-capacity adenovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Acute toxicity after high-dose systemic injection of helper-dependent adenoviral vectors into nonhuman primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

PEGylated helper-dependent adenoviral vectors: highly efficient vectors with an enhanced safety profile

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Evaluation of polyethylene glycol modification of first-generation and helper-dependent adenoviral vectors to reduce innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Vaccination with helper-dependent adenovirus enhances the generation of transgene-specific CTL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Persistence in muscle of an adenoviral vector that lacks all viral genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha1-antitrypsin with negligible toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

A gene-deleted adenoviral vector results in phenotypic correction of canine hemophilia B without liver toxicity or thrombocytopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Sustained human factor VIII expression in hemophilia A mice following systemic delivery of a gutless adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Long-Term Stable Expression of Human Apolipoprotein A-I Mediated by Helper-Dependent Adenovirus Gene Transfer Inhibits Atherosclerosis Progression and Remodels Atherosclerotic Plaques in a Mouse Model of Familial Hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Long-term stable correction of low-density lipoprotein receptor-deficient mice with a helper-dependent adenoviral vector expressing the very low-density lipoprotein receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Helper-dependent adenoviral vector-mediated long-term expression of human apolipoprotein A-I reduces atherosclerosis in apo E-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Long-term correction of ornithine transcarbamylase deficiency by WPRE-mediated overexpression using a helper-dependent adenovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Liver-specific alpha 2 interferon gene expression results in protection from induced hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Helper-dependent adenoviral vector-mediated delivery of woodchuck-specific genes for alpha interferon (IFN-alpha) and IFN-gamma: IFN-alpha but not IFN-gamma reduces woodchuck hepatitis virus replication in chronic infection in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Extensive cross-reactivity of adenovirus-specific cytotoxic T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Adenovirus-mediated regulable target gene expression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Tight control of gene expression by a helper-dependent adenovirus vector carrying the rtTA2(s)-M2 tetracycline transactivator and repressor system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

In vivo ligand-inducible regulation of gene expression in a gutless adenoviral vector system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Episomal persistence of recombinant adenoviral vector genomes during the cell cycle in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Helper-dependent adenoviral vectors containing modified fiber for improved transduction of developing and mature muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Targeting of high-capacity adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

X chromosome-linked muscular dystrophy (mdx) in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Sustained improvement of muscle function one year after full-length dystrophin gene transfer into mdx mice by a gutted helper-dependent adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Prolonged dystrophin expression and functional correction of mdx mouse muscle following gene transfer with a helper-dependent (gutted) adenovirus-encoding murine dystrophin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Comparison of high-capacity and first-generation adenoviral vector gene delivery to murine muscle in utero

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Functional correction of adult mdx mouse muscle using gutted adenoviral vectors expressing full-length dystrophin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Prolonged transgene expression mediated by a helper-dependent adenoviral vector (hdAd) in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Acute direct adenoviral vector cytotoxicity and chronic, but not acute, inflammatory responses correlate with decreased vector-mediated transgene expression in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Autologous transplantation of genetically modified iris pigment epithelial cells: a promising concept for the treatment of age-related macular degeneration and other disorders of the eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Intraocular gutless adenoviral-vectored VEGF stimulates anterior segment but not retinal neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Early adenoviral gene expression mediates immunosuppression by transduced dendritic cell (DC): implications for immunotherapy using genetically modified DC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Improved vascular gene transfer with a helper-dependent adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Protection of Cftr knockout mice from acute lung infection by a helper-dependent adenoviral vector expressing Cftr in airway epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Transfer of the full-length dystrophin-coding sequence into muscle cells by a dual high-capacity hybrid viral vector with site-specific integration ability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Long-term transgene expression in proliferating cells mediated by episomally maintained high-capacity adenovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Immunosuppression by FK506 markedly prolongs expression of adenovirus-delivered transgene in skeletal muscles of adult dystrophic [mdx] mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

7 January 2021

Effect of the E4 region on the persistence of transgene expression from adenovirus vectors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

7 January 2021

Stable transfer of a mouse dihydrofolate reductase gene into a deficient cell line using human adenovirus vector

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

7 January 2021

Long-term in vivo transduction of neurons throughout the rat CNS using novel helper-dependent CAV-2 vectors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

7 January 2021

Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

7 January 2021

Transient immunosuppression with deoxyspergualin improves longevity of transgene expression and ability to readminister adenoviral vector to the mouse lung

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

7 January 2021

Immunomodulation with FK506 around the time of intravenous re-administration of an adenoviral vector facilitates gene transfer into primed rat liver

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

7 January 2021

A phase I study of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator gene to a lung segment of individuals with cystic fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

7 January 2021

"Sero-switch" adenovirus-mediated in vivo gene transfer: circumvention of anti-adenovirus humoral immune defenses against repeat adenovirus vector administration by changing the adenovirus serotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

7 January 2021

Toxicity associated with repeated administration of first-generation adenovirus vectors does not occur with a helper-dependent vector.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

7 January 2021

Humoral immune response in mice against a circulating antigen induced by adenoviral transfer is strictly dependent on expression in antigen-presenting cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

7 January 2021

Use of a liver-specific promoter reduces immune response to the transgene in adenoviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

7 January 2021

Circumvention of anti-adenovirus neutralizing immunity by administration of an adenoviral vector of an alternate serotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

7 January 2021

Circumvention of immunity to the adenovirus major coat protein hexon.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302612

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302612

2 references

Consolidated OpenCitations Corpus – April 2017

3924288

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16231052%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

3924288

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

3924288