(Q28281092)

English

The c-Jun N-terminal protein kinase signaling pathway mediates Bax activation and subsequent neuronal apoptosis through interaction with Bim after transient focal cerebral ischemia

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356200%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

The c-Jun N-terminal protein kinase signaling pathway mediates Bax activation and subsequent neuronal apoptosis through interaction with Bim after transient focal cerebral ischemia (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356200%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

cerebral infarction

1 reference

based on heuristic

inferred from title

apoptotic process

1 reference

based on heuristic

inferred from title

author name string

Shuzo Okuno

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356200%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Atsushi Saito

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356200%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Takeshi Hayashi

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356200%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Pak H Chan

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356200%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

language of work or name

0 references

publication date

1 September 2004

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356200%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356200%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

24

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356200%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

36

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356200%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

7879-7887

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356200%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

c-Jun functions as a calcium-regulated transcriptional activator in the absence of JNK/SAPK1 activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial release of cytochrome c corresponds to the selective vulnerability of hippocampal CA1 neurons in rats after transient global cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of cell death-associated phospho-c-Jun and p53-activated gene 608 in hippocampal CA1 neurons following global ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JNK and p38 stresskinases--degenerative effectors of signal-transduction-cascades in the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcineurin-mediated BAD dephosphorylation activates the caspase-3 apoptotic cascade in traumatic spinal cord injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction by the JNK group of MAP kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Programmed cell death in cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BH3-only Bcl-2 family members are coordinately regulated by the JNK pathway and require Bax to induce apoptosis in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of mitogen- and stress-activated kinases in ischemic injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JNK phosphorylation and activation of BAD couples the stress-activated signaling pathway to the cell death machinery

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential role for the BH3-only protein Bim but redundant roles for Bax, Bcl-2, and Bcl-w in the control of granulocyte survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposite reaction of ERK and JNK in ischemia vulnerable and resistant regions of hippocampus: involvement of mitochondria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early modifications in the expression of mitogen-activated protein kinase (MAPK/ERK), stress-activated kinases SAPK/JNK and p38, and their phosphorylated substrates following focal cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between XIAP and Smac/DIABLO in the mouse brain after transient focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A critical role of neural-specific JNK3 for ischemic apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of bax protein levels in neurons following cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of SOD1 in transgenic rats protects vulnerable neurons against ischemic damage after global cerebral ischemia and reperfusion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytosolic redistribution of cytochrome c after transient focal cerebral ischemia in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15356200

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.1745-04.2004

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356200%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356200%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356200%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

ResearchGate publication ID

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