(Q28281399)

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Roles for proteolysis and trafficking in notch maturation and signal transduction

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Roles for proteolysis and trafficking in notch maturation and signal transduction (English)

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Y M Chan

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Y N Jan

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2

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language of work or name

English

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publication date

21 August 1998

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published in

Cell

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volume

94

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page(s)

423-6

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issue

4

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981583-4

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7 January 2021

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Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981583-4

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7 January 2021

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The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

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Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

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The suppressor of hairless protein participates in notch receptor signaling.

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LIN-12/Notch signaling: lessons from worms and flies

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Presenilins and Alzheimer's disease

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The LIN-12/Notch signaling pathway and its regulation

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Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.

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Indirect evidence for Delta-dependent intracellular processing of notch in Drosophila embryos

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Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei

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7 January 2021

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The Notch1 receptor is cleaved constitutively by a furin-like convertase

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Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis

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Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs

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7 January 2021

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Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

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7 January 2021

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Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease

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7 January 2021

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Nuclear access and action of notch in vivo

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7 January 2021

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Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo

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DOI

10.1016/S0092-8674(00)81583-4

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PubMed ID

9727485

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(Q28281399)

Roles for proteolysis and trafficking in notch maturation and signal transduction

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