(Q28285472)

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The RTS,S malaria vaccine

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Europe PubMed Central

The RTS,S malaria vaccine (English)

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based on heuristic

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based on heuristic

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malaria vaccine

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based on heuristic

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Thomas L. Richie

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Thomas L Richie

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Sofia Casares

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Teodor-Doru Brumeanu

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12 July 2010

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28

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31

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4880-94

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Malaria disaster in Africa

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https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Protective Immunity produced by the Injection of X-irradiated Sporozoites of Plasmodium berghei

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Structure of the Gene Encoding the Immunodominant Surface Antigen on the Sporozoite of the Human Malaria Parasite Plasmodium falciparum

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DNA Cloning ofPlasmodium falciparumCircumsporozoite Gene: Amino Acid Sequence of Repetitive Epitope

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Restricted T-cell epitope diversity in the circumsporozoite protein from Plasmodium falciparum populations prevalent in Iran.

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Comparison of circumsporozoite proteins from avian and mammalian malarias: biological and phylogenetic implications.

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The Plasmodium circumsporozoite protein is involved in mosquito salivary gland invasion by sporozoites

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The malaria circumsporozoite protein: interaction of the conserved regions I and II-plus with heparin-like oligosaccharides in heparan sulfate.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Structural and immunological analysis of circumsporozoite protein peptides: a further step in the identification of potential components of a minimal subunit-based, chemically synthesised antimalarial vaccine

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Human T-cell recognition of the circumsporozoite protein of plasmodium falciparum: Immunodominant T-cell domains map to the polymorphic regions of the molecule

1 reference

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Use of adjuvant containing mycobacterial cell-wall skeleton, monophosphoryl lipid A, and squalane in malaria circumsporozoite protein vaccine

1 reference

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Safety, immunogenicity, and efficacy of Plasmodium falciparum repeatless circumsporozoite protein vaccine encapsulated in liposomes

1 reference

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7 January 2021

Safety and immunogenicity in man of a synthetic peptide malaria vaccine against Plasmodium falciparum sporozoites

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Low prevalence of antibodies to preerythrocytic but not blood-stage Plasmodium falciparum antigens in an area of unstable malaria transmission compared to prevalence in an area of stable malaria transmission

1 reference

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Synthesis and assembly of hepatitis B virus surface antigen particles in yeast

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Safety, immunogenicity, and efficacy of a recombinantly produced Plasmodium falciparum circumsporozoite protein-hepatitis B surface antigen subunit vaccine.

1 reference

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7 January 2021

Adjuvants for malaria vaccines

1 reference

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The immunogenicity-enhancing effect of emulsion vaccine adjuvants is independent of the dispersion type and antigen release rate--a revisit of the role of the hydrophile-lipophile balance (HLB) value

1 reference

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MF59-adjuvanted vaccines: increased immunogenicity with an optimal safety profile

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Taking toll: lipid A mimetics as adjuvants and immunomodulators

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GlaxoSmithKline Adjuvant Systems in vaccines: concepts, achievements and perspectives

1 reference

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Improved T cell responses to Plasmodium falciparum circumsporozoite protein in mice and monkeys induced by a novel formulation of RTS,S vaccine antigen

1 reference

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7 January 2021

Adenovirus 5 and 35 vectors expressing Plasmodium falciparum circumsporozoite surface protein elicit potent antigen-specific cellular IFN-gamma and antibody responses in mice.

1 reference

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7 January 2021

Safety and clinical outcome of experimental challenge of human volunteers with Plasmodium falciparum-infected mosquitoes: an update

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. RTS,S Malaria Vaccine Evaluation Group

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

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Efficacy of recombinant circumsporozoite protein vaccine regimens against experimental Plasmodium falciparum malaria.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

A phase I/IIa safety, immunogenicity, and efficacy bridging randomized study of a two-dose regimen of liquid and lyophilized formulations of the candidate malaria vaccine RTS,S/AS02A in malaria-naïve adults.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Phase 2a trial of 0, 1, and 3 month and 0, 7, and 28 day immunization schedules of malaria vaccine RTS,S/AS02 in malaria-naïve adults at the Walter Reed Army Institute of Research

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protection

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Long-term efficacy and immune responses following immunization with the RTS,S malaria vaccine.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Sterile protection against Plasmodium knowlesi in rhesus monkeys from a malaria vaccine: comparison of heterologous prime boost strategies

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Priming with an adenovirus 35-circumsporozoite protein (CS) vaccine followed by RTS,S/AS01B boosting significantly improves immunogenicity to Plasmodium falciparum CS compared to that with either malaria vaccine alone

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Heterologous prime-boost immunization in rhesus macaques by two, optimally spaced particle-mediated epidermal deliveries of Plasmodium falciparum circumsporozoite protein-encoding DNA, followed by intramuscular RTS,S/AS02A.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

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Induction in humans of CD8+ and CD4+ T cell and antibody responses by sequential immunization with malaria DNA and recombinant protein.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

A clinical trial of prime-boost immunisation with the candidate malaria vaccines RTS,S/AS02A and MVA-CS.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

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A DNA prime-modified vaccinia virus ankara boost vaccine encoding thrombospondin-related adhesion protein but not circumsporozoite protein partially protects healthy malaria-naive adults against Plasmodium falciparum sporozoite challenge.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Safety, immunogenicity, and efficacy of prime-boost immunization with recombinant poxvirus FP9 and modified vaccinia virus Ankara encoding the full-length Plasmodium falciparum circumsporozoite protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

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Calculation of liver-to-blood inocula, parasite growth rates, and preerythrocytic vaccine efficacy, from serial quantitative polymerase chain reaction studies of volunteers challenged with malaria sporozoites

1 reference

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Acquired immunity to malaria

1 reference

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Insights into long-lasting protection induced by RTS,S/AS02A malaria vaccine: further results from a phase IIb trial in Mozambican children

1 reference

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Efficacy of RTS,S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in The Gambia: a randomised trial

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Evaluation of RTS,S/AS02A and RTS,S/AS01B in adults in a high malaria transmission area.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Long-term safety and efficacy of the RTS,S/AS02A malaria vaccine in Mozambican children

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Safety of the RTS,S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Safety and immunogenicity of RTS,S/AS02D malaria vaccine in infants

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Evaluation of two formulations of adjuvanted RTS, S malaria vaccine in children aged 3 to 5 years living in a malaria-endemic region of Mozambique: a Phase I/IIb randomized double-blind bridging trial

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Do we still need a malaria vaccine?

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

RTS,S/AS02A malaria vaccine does not induce parasite CSP T cell epitope selection and reduces multiplicity of infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

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Protective CD8 T cells against Plasmodium liver stages: immunobiology of an 'unnatural' immune response.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Sterile protection against malaria is independent of immune responses to the circumsporozoite protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Potent induction of focused Th1-type cellular and humoral immune responses by RTS,S/SBAS2, a recombinant Plasmodium falciparum malaria vaccine.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

A phase I safety and immunogenicity trial with the candidate malaria vaccine RTS,S/SBAS2 in semi-immune adults in The Gambia.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Safety and immunogenicty of RTS,S/AS02A candidate malaria vaccine in Gambian children

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Randomized controlled trial of RTS,S/AS02D and RTS,S/AS01E malaria candidate vaccines given according to different schedules in Ghanaian children

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

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A randomized trial assessing the safety and immunogenicity of AS01 and AS02 adjuvanted RTS,S malaria vaccine candidates in children in Gabon

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

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Opsonization by antigen-specific antibodies as a mechanism of protective immunity induced by Plasmodium falciparum circumsporozoite protein-based vaccine.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Protective immunity induced with malaria vaccine, RTS,S, is linked to Plasmodium falciparum circumsporozoite protein-specific CD4+ and CD8+ T cells producing IFN-gamma.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Plasmodium falciparum-specific cellular immune responses after immunization with the RTS,S/AS02D candidate malaria vaccine in infants living in an area of high endemicity in Mozambique

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Immune evasion by malaria parasites: a challenge for vaccine development

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Peripherally induced Treg: mode, stability, and role in specific tolerance.

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Boosting BCG vaccination with MVA85A down-regulates the immunoregulatory cytokine TGF-beta1.

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https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

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Expression of genes associated with immunoproteasome processing of major histocompatibility complex peptides is indicative of protection with adjuvanted RTS,S malaria vaccine.

1 reference

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Mobilizing the proteolytic machine: cell biological roles of proteasome activators and inhibitors

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Protection of rhesus monkeys by a DNA prime/poxvirus boost malaria vaccine depends on optimal DNA priming and inclusion of blood stage antigens

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.05.033

7 January 2021

Induction of multi-antigen multi-stage immune responses against Plasmodium falciparum in rhesus monkeys, in the absence of antigen interference, with heterologous DNA prime/poxvirus boost immunization.

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Genetically engineered, attenuated whole-cell vaccine approaches for malaria

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Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells

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MALVAC 2008: Measures of efficacy of malaria vaccines in phase 2b and phase 3 trials--scientific, regulatory and public health perspectives

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Assessment of the Protective Efficacy of Vaccines against Common Diseases Using Case-Control and Cohort Studies

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10.1016/J.VACCINE.2010.05.033

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

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