(Q28286394)

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Germline and somatic polymerase ε and δ mutations define a new class of hypermutated colorectal and endometrial cancers

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Germline and somatic polymerase ε and δ mutations define a new class of hypermutated colorectal and endometrial cancers (English)

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2

Ian Tomlinson

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author name string

Sarah Briggs

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1

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language of work or name

English

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publication date

June 2013

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published in

Journal of Pathology

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volume

230

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page(s)

148-53

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issue

2

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cites work

DNA polymerase ε and δ exonuclease domain mutations in endometrial cancer

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PubMed Central

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Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

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20 March 2017

Comprehensive molecular characterization of human colon and rectal cancer

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PubMed Central

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20 March 2017

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

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20 March 2017

Division of labor at the eukaryotic replication fork

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20 March 2017

Yeast DNA polymerase epsilon participates in leading-strand DNA replication

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20 March 2017

In vivo consequences of putative active site mutations in yeast DNA polymerases alpha, epsilon, delta, and zeta

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20 March 2017

Pathway correcting DNA replication errors in Saccharomyces cerevisiae

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20 March 2017

Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity

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20 March 2017

The 3' to 5' exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replication

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20 March 2017

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

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7 April 2017

MLH1-silenced and non-silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes

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29 September 2017

A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in genomic instability

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29 September 2017

DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice

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Increased rates of genomic deletions generated by mutations in the yeast gene encoding DNA polymerase delta or by decreases in the cellular levels of DNA polymerase delta

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29 September 2017

Mutator phenotypes caused by substitution at a conserved motif A residue in eukaryotic DNA polymerase delta

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2 June 2018

Amino acid changes coded by bacteriophage T4 DNA polymerase mutator mutants. Relating structure to function

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https://pubmed.ncbi.nlm.nih.gov/23447401

retrieved

12 December 2020

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Identifiers

DOI

10.1002/PATH.4185

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

594491

OpenCitations bibliographic resource ID

594491

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stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

594491

ResearchGate publication ID

235750640

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(Q28286394)

Germline and somatic polymerase ε and δ mutations define a new class of hypermutated colorectal and endometrial cancers

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