(Q28288423)

Downstream processing of monoclonal antibodies--application of platform approaches

published in

Monoclonal Antibodies

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volume

2

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issue

5

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page(s)

480-99

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cites work

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High-throughput screening of packed-bed chromatography coupled with SELDI-TOF MS analysis: monoclonal antibodies versus host cell protein

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The use of chitosan as a flocculant in mammalian cell culture dramatically improves clarification throughput without adversely impacting monoclonal antibody recovery

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Alternatives to chromatographic separations

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Future of antibody purification

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Basic concepts in Q membrane chromatography for large-scale antibody production

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Plant cell cultures for the production of recombinant proteins

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Downstream processing of recombinant proteins from transgenic feedstock

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Alternative bioseparation operations: life beyond packed-bed chromatography

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Functional integrity of intravenous immunoglobulin following irradiation with a virucidal dose of gamma radiation

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Generic/matrix evaluation of SV40 clearance by anion exchange chromatography in flow-through mode

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Virus inactivation by high intensity broad spectrum pulsed light

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Protein separation using membrane chromatography: opportunities and challenges

29 September 2017

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Industrial purification of pharmaceutical antibodies: development, operation, and validation of chromatography processes

29 September 2017

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Capture of latex beads, bacteria, endotoxin, and viruses by charge-modified filters

29 September 2017

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Endotoxin removal by charge-modified filters

29 September 2017

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High-temperature short-time heat inactivation of HIV and other viruses in human blood plasma.

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Chromatography of lipophilic proteins on adsorbents containing mixed hydrophobic and ionic groups

29 September 2017

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Evaluation of depth filtration to remove prion challenge from an immune globulin preparation

2 June 2018

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Exploitation of the adsorptive properties of depth filters for host cell protein removal during monoclonal antibody purification.

21 January 2018

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https://api.crossref.org/works/10.4161%2FMABS.2.5.12645

Elution of antibodies from a Protein-A column by aqueous arginine solutions

21 January 2018

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Antibody variable region interactions with Protein A: implications for the development of generic purification processes.

21 January 2018

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Impact of multiple re-use of anion-exchange chromatography media on virus removal

21 January 2018

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Weak partitioning chromatography for anion exchange purification of monoclonal antibodies.

21 January 2018

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An exclusion mechanism in ion exchange chromatography

21 January 2018

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Factorial screening of antibody purification processes using three chromatography steps without protein A.

21 January 2018

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pH-conductivity hybrid gradient cation-exchange chromatography for process-scale monoclonal antibody purification

21 January 2018

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Hydrophobic interaction chromatography at low salt concentration for the capture of monoclonal antibodies

21 January 2018

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https://api.crossref.org/works/10.4161%2FMABS.2.5.12645

Comparison of hydrophobic charge induction chromatography with affinity chromatography on protein A for harvest and purification of antibodies

21 January 2018

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High-throughput screening of chromatographic separations: II. Hydrophobic interaction

21 January 2018

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High-throughput screening of chromatographic separations: III. Monoclonal antibodies on ceramic hydroxyapatite.

21 January 2018

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High-throughput screening of chromatographic separations: IV. Ion-exchange.

21 January 2018

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https://api.crossref.org/works/10.4161%2FMABS.2.5.12645

Separation of biomolecules using adsorptive membranes

21 January 2018

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Performance of a membrane adsorber for trace impurity removal in biotechnology manufacturing.

21 January 2018

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New Q membrane scale-down model for process-scale antibody purification.

21 January 2018

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Separation of protein charge variants by ultrafiltration

21 January 2018

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Effect of solution pH and ionic strength on the separation of albumin from immunoglobulins (IgG) by selective filtration

21 January 2018

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https://api.crossref.org/works/10.4161%2FMABS.2.5.12645

High performance tangential flow filtration

21 January 2018

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https://api.crossref.org/works/10.4161%2FMABS.2.5.12645

Separation of monoclonal antibody alemtuzumab monomer and dimers using ultrafiltration.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.2.5.12645

Increasing the capacity of parvovirus-retentive membranes: performance of the Viresolve Prefilter.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.2.5.12645

Inactivation of viruses during ultraviolet light treatment of human intravenous immunoglobulin and albumin.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.2.5.12645

Design of a UV-C irradiation process for the inactivation of viruses in protein solutions.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.2.5.12645

Enveloped virus inactivation by caprylate: a robust alternative to solvent-detergent treatment in plasma derived intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.2.5.12645

Properties of a new intravenous immunoglobulin (IGIV-C, 10%) produced by virus inactivation with caprylate and column chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.2.5.12645

Gamma irradiation of intravenous immunoglobulin.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958570

Fragments of protein A eluted during protein A affinity chromatography

27 November 2018

1 reference

12 December 2020

Bracketed generic inactivation of rodent retroviruses by low pH treatment for monoclonal antibodies and recombinant proteins

1 reference

12 December 2020

Hydrophobic charge induction chromatography: salt independent protein adsorption and facile elution with aqueous buffers

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12 December 2020

Induced flocculation of animal cells in suspension culture

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12 December 2020

Purification and analytical characterization of an anti-CD4 monoclonal antibody for human therapy

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12 December 2020

Salt-promoted adsorption: recent developments

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12 December 2020

Binding capacity differences for antibodies and Fc-fusion proteins on protein A chromatographic materials

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12 December 2020

Characterization of a generic monoclonal antibody harvesting system for adsorption of DNA by depth filters and various membranes

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12 December 2020

New method for the selective capture of antibodies under physiological conditions

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12 December 2020

Points to consider in the manufacture and testing of monoclonal antibody products for human use (1997). U.S. Food and Drug Administration Center for Biologics Evaluation and Research

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12 December 2020

Performance comparison of protein A affinity-chromatography sorbents for purifying recombinant monoclonal antibodies

1 reference

12 December 2020

Membrane ion-exchange chromatography for process-scale antibody purification

1 reference

12 December 2020

Assessment of a disc stack centrifuge for use in mammalian cell separation

1 reference

12 December 2020

High-throughput screening of chromatographic separations: I. Method development and column modeling

1 reference

12 December 2020

Effect of solution pH on protein transport through ultrafiltration membranes

1 reference

12 December 2020

Single-step purification of bispecific monoclonal antibodies for immunotherapeutic use by hydrophobic interaction chromatography

1 reference

12 December 2020

Implementation of a crystallization step into the purification process of a recombinant protein

1 reference

12 December 2020

Identifiers

DOI

10.4161/MABS.2.5.12645

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PubMed publication ID

20647768

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