(Q28288539)

24 June 2017

title

A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction (English)

1 reference

24 June 2017

0 references

Chieri Tomomori-Sato

3

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Joan W. Conaway

object named as

Joan W Conaway

5

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author name string

Kuang-Lei Tsai

1

1 reference

24 June 2017

Shigeo Sato

2

1 reference

24 June 2017

Ronald C Conaway

4

1 reference

24 June 2017

Francisco J Asturias

6

1 reference

24 June 2017

language of work or name

English

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publication date

7 April 2013

1 reference

Nature Structural & Molecular Biology

24 June 2017

published in

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24 June 2017

volume

20

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24 June 2017

issue

5

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24 June 2017

page(s)

611-619

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Structure of the Mediator head module

24 June 2017

cites work

1 reference

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Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II

20 March 2017

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Interaction of the Mediator Head Module with RNA Polymerase II

20 March 2017

1 reference

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The structure of CDK8/CycC implicates specificity in the CDK/cyclin family and reveals interaction with a deep pocket binder

20 March 2017

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Architecture of the Mediator head module

20 March 2017

1 reference

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Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly

20 March 2017

1 reference

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Mediator head module structure and functional interactions

20 March 2017

1 reference

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Mediator structural conservation and implications for the regulation mechanism

20 March 2017

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The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator

20 March 2017

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CDK8 is a stimulus-specific positive coregulator of p53 target genes

20 March 2017

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Mediator as a general transcription factor

20 March 2017

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20 March 2017

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Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3

20 March 2017

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20 March 2017

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Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation

20 March 2017

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Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s

20 March 2017

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Structure, function, and activator-induced conformations of the CRSP coactivator

20 March 2017

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20 March 2017

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20 March 2017

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Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases

20 March 2017

1 reference

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The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain

20 March 2017

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20 March 2017

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A kinase-cyclin pair in the RNA polymerase II holoenzyme.

20 March 2017

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Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II

20 March 2017

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Conformational flexibility of metazoan fatty acid synthase enables catalysis

20 March 2017

1 reference

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Plat-E: an efficient and stable system for transient packaging of retroviruses

20 March 2017

1 reference

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7 April 2017

1 reference

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Identifying conformational states of macromolecules by eigen-analysis of resampled cryo-EM images

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648612

CDK8 is a positive regulator of transcriptional elongation within the serum response network

29 September 2017

1 reference

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29 September 2017

1 reference

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The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II.

29 September 2017

1 reference

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29 September 2017

1 reference

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Structural organization of yeast and mammalian mediator complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648612

Evidence for a mediator cycle at the initiation of transcription.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648612

Three-dimensional reconstruction from a single-exposure, random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli

29 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648612

29 September 2017

A mediator required for activation of RNA polymerase II transcription in vitro

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648612

The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648612

Mediator influences Schizosaccharomyces pombe RNA polymerase II-dependent transcription in vitro.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648612

Resolution of factors required for the initiation of transcription by yeast RNA polymerase II.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648612

Association of an activator with an RNA polymerase II holoenzyme

2 June 2018

1 reference

The structural and functional organization of the yeast mediator complex

21 January 2018

1 reference

Conserved structures of mediator and RNA polymerase II holoenzyme

31 March 2020

1 reference

Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.2549

1 reference

Dimensions Publication ID

24 June 2017

1025524527

0 references

PMC publication ID

3648612

0 references

1 reference