(Q28288682)

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The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells

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4 January 2020

The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells (English)

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4 January 2020

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Araceli del Arco

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4 January 2020

Jorgina Satrustegui Gil Delgado

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4 January 2020

Pierre Maechler

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Blanca Rubi

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4 January 2020

Clarissa Bartley

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19 October 2004

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4 January 2020

Journal of Biological Chemistry

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4 January 2020

279

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4 January 2020

55659-55666

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4 January 2020

Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409303200

21 January 2018

Mitochondria as the conductor of metabolic signals for insulin exocytosis in pancreatic beta-cells.

1 reference

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21 January 2018

Metabolic and functional studies on isolated islets in a new rat model of type 2 diabetes

1 reference

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21 January 2018

Role of NADH shuttles in glucose-induced insulin secretion from fetal beta-cells

1 reference

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Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion

1 reference

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21 January 2018

A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli

1 reference

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21 January 2018

Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues

1 reference

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21 January 2018

Molecular cloning of Aralar, a new member of the mitochondrial carrier superfamily that binds calcium and is present in human muscle and brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409303200

21 January 2018

Citrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondria

1 reference

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21 January 2018

Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells

1 reference

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21 January 2018

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

1 reference

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21 January 2018

Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome

1 reference

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21 January 2018

Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells.

1 reference

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21 January 2018

Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line.

1 reference

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21 January 2018

9 Enzymic determination of lactic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409303200

21 January 2018

Mitochondria-derived glutamate at the interplay between branched-chain amino acid and glucose-induced insulin secretion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409303200

21 January 2018

Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409303200

21 January 2018

Expression of the aspartate/glutamate mitochondrial carriers aralar1 and citrin during development and in adult rat tissues.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409303200

21 January 2018

Separation of the glucose-stimulated cytoplasmic and mitochondrial NAD(P)H responses in pancreatic islet beta cells

1 reference

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21 January 2018

Effects of calcium ions and adenosine diphosphate on the activities of NAD+-linked isocitrate dehydrogenase from the radular muscles of the whelk and flight muscles of insects

1 reference

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21 January 2018

Some properties of pyruvate and 2-oxoglutarate oxidation by blowfly flight-muscle mitochondria

1 reference

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21 January 2018

Histochemical evidence for pathways insulin cells use to oxidize glycolysis-derived NADH.

1 reference

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21 January 2018

Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells

1 reference

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21 January 2018

Switch to anaerobic glucose metabolism with NADH accumulation in the beta-cell model of mitochondrial diabetes. Characteristics of betaHC9 cells deficient in mitochondrial DNA transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409303200

21 January 2018

A nuclear magnetic resonance-based demonstration of substantial oxidative L-alanine metabolism and L-alanine-enhanced glucose metabolism in a clonal pancreatic beta-cell line: metabolism of L-alanine is important to the regulation of insulin secreti

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409303200

21 January 2018

Influence of the Malate-Aspartate Shuttle on Oxidative Metabolism in Synaptosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409303200

21 January 2018

Recombinant expression of the Ca(2+)-sensitive aspartate/glutamate carrier increases mitochondrial ATP production in agonist-stimulated Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409303200

21 January 2018

Glucose-stimulated insulin secretion correlates with changes in mitochondrial and cytosolic Ca2+ in aequorin-expressing INS-1 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409303200

21 January 2018

Insulin secretion from toadfish islet tissue stimulated by pyridine nucleotides.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409303200

21 January 2018

Pyridine nucleotide stimulation of insulin release from isolated toadfish insulin secretion granules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409303200

21 January 2018

Uptake of NADPH by Islet Secretion Granule Membranes1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409303200

21 January 2018

The structure and function of the ATP-sensitive K+ channel in insulin-secreting pancreatic beta-cells

1 reference

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21 January 2018

Synergism of protein kinase A, protein kinase C, and myosin light-chain kinase in the secretory cascade of the pancreatic beta-cell

1 reference

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21 January 2018

Involvement of conventional kinesin in glucose-stimulated secretory granule movements and exocytosis in clonal pancreatic beta-cells.

1 reference

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21 January 2018

Increase in cellular glutamate levels stimulates exocytosis in pancreatic beta-cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409303200

21 January 2018

Effect of mitochondrial and/or cytosolic glycerol 3-phosphate dehydrogenase overexpression on glucose-stimulated insulin secretion from MIN6 and HIT cells

1 reference

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21 January 2018

Mouse lacking NAD+-linked glycerol phosphate dehydrogenase has normal pancreatic beta cell function but abnormal metabolite pattern in skeletal muscle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409303200

21 January 2018

Identifiers

10.1074/JBC.M409303200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15494407%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15494407%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

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