(Q40753443)

English

Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues

scientific article published on 30 January 2002

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scholarly article

1 reference

Europe PubMed Central

23 September 2017

Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues (English)

1 reference

Europe PubMed Central

23 September 2017

1 reference

based on heuristic

inferred from title

Christopher B Newgard

3

object named as

Christopher B Newgard

1 reference

Europe PubMed Central

23 September 2017

author name string

Peter A Antinozzi

1

1 reference

Europe PubMed Central

23 September 2017

Hisamitsu Ishihara

2

1 reference

Europe PubMed Central

23 September 2017

Claes B Wollheim

4

1 reference

Europe PubMed Central

23 September 2017

language of work or name

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publication date

30 January 2002

1 reference

Europe PubMed Central

23 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

23 September 2017

277

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Europe PubMed Central

23 September 2017

14

1 reference

Europe PubMed Central

23 September 2017

11746-11755

1 reference

Europe PubMed Central

23 September 2017

Metabolic coupling factors in pancreatic beta-cell signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Triggering and amplifying pathways of regulation of insulin secretion by glucose

1 reference

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21 January 2018

Activation of stimulus-secretion coupling in pancreatic beta-cells by specific products of glucose metabolism. Evidence for privileged signaling by glycolysis.

1 reference

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21 January 2018

NADH shuttle system regulates K(ATP) channel-dependent pathway and steps distal to cytosolic Ca(2+) concentration elevation in glucose-induced insulin secretion

1 reference

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21 January 2018

The stimulus-secretion coupling of glucose-induced insulin release. XXXV. The links between metabolic and cationic events

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Mitochondrial DNA is required for regulation of glucose-stimulated insulin secretion in a mouse pancreatic beta cell line, MIN6.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Effects of depletion of mitochondrial DNA in metabolism secretion coupling in INS-1 cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

The stimulus-secretion coupling of glucose-induced insulin release. Effect of exogenous pyruvate on islet function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Interrelationship of islet metabolism, adenosine triphosphate content and insulin release

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

The stimulation of insulin secretion by D-glyceraldehyde correlates with its rate of oxidation in islet cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Intracellular pH and the stimulus-secretion coupling in insulin-producing RINm5F cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Engineering of glycerol-stimulated insulin secretion in islet beta cells. Differential metabolic fates of glucose and glycerol provide insight into mechanisms of stimulus-secretion coupling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Glycerol-stimulated proinsulin biosynthesis in isolated pancreatic rat islets via adenoviral-induced expression of glycerol kinase is mediated via mitochondrial metabolism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome

1 reference

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21 January 2018

Glucose-stimulated insulin secretion correlates with changes in mitochondrial and cytosolic Ca2+ in aequorin-expressing INS-1 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Free radical modulation of insulin release in INS-1 cells exposed to alloxan

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Purification and characterization of rat brain glycerol phosphate dehydrogenase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Regulation of mitochondrial glycerol-phosphate dehydrogenase by Ca2+ within electropermeabilized insulin-secreting cells (INS-1)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Fundamental metabolic differences between hepatocytes and islet beta-cells revealed by glucokinase overexpression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic beta-cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Expression and distribution of lactate/monocarboxylate transporter isoforms in pancreatic islets and the exocrine pancreas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic beta-cell nutrient signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Modulation of glucose responsiveness of insulinoma beta-cells by graded overexpression of glucokinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Differential effects of overexpressed glucokinase and hexokinase I in isolated islets. Evidence for functional segregation of the high and low Km enzymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

The mitochondrial transporter family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Glucose sensing in pancreatic beta-cells: a model for the study of other glucose-regulated cells in gut, pancreas, and hypothalamus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Phorbol Myristate Acetate: Effect of a Tumor Promoter on Insulin Release from Isolated Rat Islets of Langerhans*

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Control of reversible intracellular transfer of reducing potential

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Uncoupling: new approaches to an old problem of bioenergetics

1 reference

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21 January 2018

Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Uncoupling protein 2: a possible link between fatty acid excess and impaired glucose-induced insulin secretion?

1 reference

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21 January 2018

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108462200

21 January 2018

Beta-cell adaptation and decompensation during the progression of diabetes.

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M108462200

1 reference

Europe PubMed Central

23 September 2017

1 reference

Europe PubMed Central

23 September 2017

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