(Q28289570)

P21 (RAC1) activated kinase 5

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Tanya Nekrasova

1

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Michelle L Jobes

2

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Jenhao H Ting

3

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George C Wagner

4

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Audrey Minden

PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

5

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language of work or name

English

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publication date

1 October 2008

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published in

Developmental Biology

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volume

322

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issue

1

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page(s)

95-108

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006

PAK3 mutation in nonsyndromic X-linked mental retardation

7 January 2021

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Missense mutation in PAK3, R67C, causes X-linked nonspecific mental retardation.

7 January 2021

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GEFT, a Rho family guanine nucleotide exchange factor, regulates neurite outgrowth and dendritic spine formation

7 January 2021

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Pak4 induces premature senescence via a pathway requiring p16INK4/p19ARF and mitogen-activated protein kinase signaling

7 January 2021

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Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties

7 January 2021

1 reference

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p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD

7 January 2021

1 reference

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Cytoskeletal changes regulated by the PAK4 serine/threonine kinase are mediated by LIM kinase 1 and cofilin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006

PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006

p21-activated protein kinase: a crucial component of morphological signaling?

7 January 2021

1 reference

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Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells

7 January 2021

1 reference

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Enhancement of learning and memory after activation of cerebral Rho GTPases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006

LIM-kinase1 hemizygosity implicated in impaired visuospatial constructive cognition

7 January 2021

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Hippocampal LTP is accompanied by enhanced F-actin content within the dendritic spine that is essential for late LTP maintenance in vivo

7 January 2021

1 reference

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Death receptor-induced activation of initiator caspase 8 is antagonized by serine/threonine kinase PAK4.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006

The serine/threonine kinase PAK4 prevents caspase activation and protects cells from apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006

A Drosophila homolog of the Rac- and Cdc42-activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures

7 January 2021

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Altered cortical synaptic morphology and impaired memory consolidation in forebrain- specific dominant-negative PAK transgenic mice

7 January 2021

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Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice

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Linkage of a commoner form of recessive amyotrophic lateral sclerosis to chromosome 15q15-q22 markers

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Pak functions downstream of Dock to regulate photoreceptor axon guidance in Drosophila

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p21-activated kinases: three more join the Pak.

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Activation of p21-activated kinase 6 by MAP kinase kinase 6 and p38 MAP kinase

7 January 2021

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The p21Rac/Cdc42-activated kinases (PAKs).

7 January 2021

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AR and ER interaction with a p21-activated kinase (PAK6)

7 January 2021

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Targeted disruption of the gene for the PAK5 kinase in mice

7 January 2021

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Role of 5-HT1-7 receptors in short- and long-term memory for an autoshaping task: intrahippocampal manipulations

7 January 2021

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Rho GTPases in neuronal morphogenesis

7 January 2021

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Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006

PAK5 kinase is an inhibitor of MARK/Par-1, which leads to stable microtubules and dynamic actin

7 January 2021

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7 January 2021

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Abnormal long-lasting synaptic plasticity and cognition in mice lacking the mental retardation gene Pak3.

7 January 2021

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Amyotrophic lateral sclerosis.

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Williams syndrome and related disorders

7 January 2021

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Spine changes associated with long-term potentiation

7 January 2021

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Cloning and characterization of PAK5, a novel member of mammalian p21-activated kinase-II subfamily that is predominantly expressed in brain

7 January 2021

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Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006

Dendritic Spine "Dysgenesis" and Mental Retardation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006

PAK4 Kinase Is Essential for Embryonic Viability and for Proper Neuronal Development

7 January 2021

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Autistic disorder and chromosomal mosaicism 46,XY[123]/46,XY,del(20)(pter --> p12.2)[10].

7 January 2021

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Mechanism of p21-activated Kinase 6-mediated Inhibition of Androgen Receptor Signaling

7 January 2021

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Emerging from the Pak: the p21-activated protein kinase family.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006

Regulation of dendritic spine morphology by the rho family of small GTPases: antagonistic roles of Rac and Rho

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006

Regulation of dendritic growth and remodeling by Rho, Rac, and Cdc42.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006

Signaling from MARK to tau: regulation, cytoskeletal crosstalk, and pathological phosphorylation.

7 January 2021

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Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006

Androgen receptor specifically interacts with a novel p21-activated kinase, PAK6

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006

Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006

Reduction of sortilin-1 in Alzheimer hippocampus and in cytokine-stressed human brain cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006

Induction of spine growth and synapse formation by regulation of the spine actin cytoskeleton

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.07.006