(Q28609670)

3 February 2017

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Europe PubMed Central

title

p21-activated protein kinase: a crucial component of morphological signaling? (English)

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3 February 2017

R. H. Daniels

1

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3 February 2017

G. M. Bokoch

series ordinal

2

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3 February 2017

publication date

1 September 1999

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Trends in Biochemical Sciences

3 February 2017

published in

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3 February 2017

volume

24

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3 February 2017

issue

9

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3 February 2017

page(s)

350–355

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Rho GTPases and the actin cytoskeleton

3 February 2017

cites work

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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The p21Rac/Cdc42-activated kinases (PAKs).

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A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

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Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis

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Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

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PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

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Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast.

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The Caenorhabditis elegans p21-activated kinase (CePAK) colocalizes with CeRac1 and CDC42Ce at hypodermal cell boundaries during embryo elongation

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Virulence and hyphal formation of Candida albicans require the Ste20p-like protein kinase CaCla4p

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A Drosophila homolog of the Rac- and Cdc42-activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures

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Pak functions downstream of Dock to regulate photoreceptor axon guidance in Drosophila

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7 January 2021

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p21-activated kinase has substrate specificity similar to Acanthamoeba myosin I heavy chain kinase and activates Acanthamoeba myosin I

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7 January 2021

Regulation of the p21-activated kinase-related Dictyostelium myosin I heavy chain kinase by autophosphorylation, acidic phospholipids, and Ca2+-calmodulin

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7 January 2021

The localization of myosin VI at the golgi complex and leading edge of fibroblasts and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulation

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7 January 2021

A novel regulator of p21-activated kinases

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7 January 2021

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7 January 2021

Identification and characterization of a novel family of serine/threonine kinases containing two N-terminal LIM motifs

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LIM-kinase1 hemizygosity implicated in impaired visuospatial constructive cognition

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Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase

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Differential effects of PAK1-activating mutations reveal activity-dependent and -independent effects on cytoskeletal regulation

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7 January 2021

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Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017