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EF-Tu, a GTPase odyssey
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Europe PubMed Central
title
EF-Tu, a GTPase odyssey
(English)
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author name string
I M Krab
series ordinal
1
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A Parmeggiani
series ordinal
2
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language of work or name
English
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publication date
26 November 1998
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published in
Biochimica et Biophysica Acta
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volume
1443
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page(s)
1-22
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issue
1-2
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cites work
Protein biosynthesis
1 reference
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reference URL
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7 January 2021
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The role of guanosine 5′-triphosphate in polypeptide chain elongation
1 reference
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The GTPase superfamily: a conserved switch for diverse cell functions
1 reference
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7 January 2021
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The GTPase superfamily: conserved structure and molecular mechanism
1 reference
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7 January 2021
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inferred from DOI database lookup
The Elongation Factor EF-Tu and Its Two Encoding Genes
1 reference
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7 January 2021
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Elongation factor Tu: a molecular switch in protein biosynthesis
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Crossref
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7 January 2021
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inferred from DOI database lookup
Mechanism of action of kirromycin-like antibiotics
1 reference
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7 January 2021
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A complex profile of protein elongation: translating chemical energy into molecular movement
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7 January 2021
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The ternary complex of EF-Tu and its role in protein biosynthesis
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7 January 2021
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Crystalline transfer factors from Escherichia coli
1 reference
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7 January 2021
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Studies on the purification and properties of factor Tu from E. coli
1 reference
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7 January 2021
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Preliminary x-ray analysis of the crystalline complex between poypeptide chain elongation factor, Tu, and GDP.
1 reference
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Crossref
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7 January 2021
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Structure of the GDP domain of EF-Tu and location of the amino acids homologous to ras oncogene proteins
1 reference
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Crossref
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7 January 2021
based on heuristic
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Refined structure of elongation factor EF-Tu from Escherichia coli
1 reference
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7 January 2021
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An alpha to beta conformational switch in EF-Tu
1 reference
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7 January 2021
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Helix unwinding in the effector region of elongation factor EF-Tu-GDP
1 reference
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Crossref
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7 January 2021
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Crystal structure of active elongation factor Tu reveals major domain rearrangements
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
The structure of the Escherichia coli EF-Tu.EF-Ts complex at 2.5 A resolution
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the EF-Tu.EF-Ts complex from Thermus thermophilus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
The inhibition of eucaryotic protein synthesis by procaryotic elongation factor Tu
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
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7 January 2021
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inferred from DOI database lookup
Structural model for the selenocysteine-specific elongation factor SelB.
1 reference
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Crossref
reference URL
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7 January 2021
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The root of the universal tree and the origin of eukaryotes based on elongation factor phylogeny.
1 reference
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Polypeptide elongation and tRNA cycling in Escherichia coli: a dynamic approach
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Kirromycin-induced modifications facilitate the separation of EF-Tu species and reveal intermolecular interactions.
1 reference
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Crossref
reference URL
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7 January 2021
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Three tuf-like genes in the kirromycin producer Streptomyces ramocissimus.
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Homologous recombination between the tuf genes of Salmonella typhimurium.
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Both genes for EF-Tu in Salmonella typhimurium are individually dispensable for growth
1 reference
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Crossref
reference URL
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inferred from DOI database lookup
Growth and translation elongation rate are sensitive to the concentration of EF-Tu.
1 reference
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Crossref
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Ribosomal genes in Escherichia coli
1 reference
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The mechanism of trans-activation of the Escherichia coli operon thrU(tufB) by the protein FIS. A model
1 reference
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Antibiotic resistance mechanisms of mutant EF-Tu species in Escherichia coli
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Cloning and sequencing of the tuf genes of Streptomyces coelicolor A3(2)
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
The tuf3 gene of Streptomyces coelicolor A3(2) encodes an inessential elongation factor Tu that is apparently subject to positive stringent control
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Elongation factor Tu1 of the antibiotic GE2270A producer Planobispora rosea has an unexpected resistance profile against EF-Tu targeted antibiotics.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Primary structure of elongation factor Tu from Escherichia coli
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The complete amino-acid sequence of elongation factor Tu from Escherichia coli
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of elongation factor Tu prevents ternary complex formation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Codon-specific missense errors in vivo.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High Specificity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetic amplification of enzyme discrimination
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Codon-dependent conformational change of elongation factor Tu preceding GTP hydrolysis on the ribosome.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Initial binding of the elongation factor Tu.GTP.aminoacyl-tRNA complex preceding codon recognition on the ribosome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
The influence of the concentrations of elongation factors and tRNAs on the dynamics and accuracy of protein biosynthesis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutant EF-Tu increases missense error in vitro
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antisuppression by mutations in elongation factor Tu.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of the mutation glycine-222----aspartic acid on the functions of elongation factor Tu.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Substitution of Val20 by Gly in elongation factor Tu. Effects on the interaction with elongation factors Ts, aminoacyl-tRNA and ribosomes.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Site-directed mutagenesis of Thermus thermophilus elongation factor Tu. Replacement of His85, Asp81 and Arg300.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutants of elongation factor Tu promote ribosomal frameshifting and nonsense readthrough.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abundance and membrane association of elongation factor Tu in E. coli
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunocytochemical localization of the elongation factor Tu in E. coli cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel properties of bacterial elongation factor Tu
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polymerization of an Escherichia coli elongation factor Tu.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of Ribosomal RNA Synthesis in vitro
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Appearance of elongation factor Tu in the outer membrane of sucrose-dependent spectinomycin-resistant mutants of Escherichia coli
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Uncoupler-induced relocation of elongation factor Tu to the outer membrane in an uncoupler-resistant mutant of Escherichia coli
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Elongation factor Tu is methylated in response to nutrient deprivation in Escherichia coli
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Bacteriophage Qβ Replicase Contains the Protein Biosynthesis Elongation Factors EF Tu and EF Ts
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Elongation factor 1 alpha, translation and the cytoskeleton
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Modification of Elongation-Factor-Tu . Guanine-Nucleotide Interaction by Kirromycin. A Comparison with the Effect of Aminoacyl-tRNA and Elongation Factor Ts
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of Guanosine Nucleotides and Their Analogs with Elongation Factor Tu from Thermus thermophilus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the elongation factors from calf brain. 2. Functional properties of EF-1 alpha, the action of physiological ligands and kirromycin.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preparation of nucleotide-free elongation factor Tu and its stabilization by the antibiotic kirromycin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Properties and regulation of the GTPase activities of elongation factors Tu and G, and of initiation factor 2
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence and identification of the nucleotide binding site for the elongation factor Tu from Thermus thermophilus HB8.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetic analysis by fluorescence of the interaction between Ras and the catalytic domain of the guanine nucleotide exchange factor Cdc25Mm
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kirromycin, an inhibitor of protein biosynthesis that acts on elongation factor Tu
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetic properties of Escherichia coli ribosomes with altered forms of S12
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
tRNA and the guanosinetriphosphatase activity of elongation factor Tu
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transfer ribonucleic acid deprived of the C-C-A 3'-extremity can interact with elongation factor Tu
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rate of elongation of polyphenylalanine in vitro
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mg2+/NH4+/polyamine system for polyuridine-dependent polyphenylalanine synthesis with near in vivo characteristics
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rate of translation of natural mRNAs in an optimized in vitro system
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ribosome as affinity matrix': efficient purification scheme for translation factors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional Role of the Noncatalytic Domains of Elongation Factor Tu in the Interactions with Ligands†
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New antibiotic that acts specifically on the GTP-bound form of elongation factor Tu.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enacyloxin IIa, an inhibitor of protein biosynthesis that acts on elongation factor Tu and the ribosome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation by monovalent and divalent cations of the guanosine-5'-triphosphatase activity dependent on elongation factor Tu
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Binding of Kirromycin to Elongation Factor Tu. Structural Alterations are Responsible for the Inhibitory Action
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kirromycin drastically reduces the affinity of Escherichia coli elongation factor Tu for aminoacyl-tRNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of Kirromycin on Elongation Factor Tu. Location of the Catalytic Center for Ribosome . Elongation-Factor-Tu GTPase Activity on the Elongation Factor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pulvomycin, an inhibitor of protein biosynthesis preventing ternary complex formation between elongation factor Tu, GTP, and aminoacyl-tRNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific alterations of the EF-Tu polypeptide chain considered in the light of its three-dimensional structure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translational activities of EF-Tu [G222D] which cannot be reconciled with the classical scheme of the polypeptide chain elongation cycle.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of EF-Tu and other translation components in determining translocation step size.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutant ribosomes can generate dominant kirromycin resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pulvomycin-resistant mutants of E.coli elongation factor Tu.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the elongation factors from calf brain. 3. Properties of the GTPase activity of EF-1 alpha and mode of action of kirromycin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Properties of a genetically engineered G domain of elongation factor Tu.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Properties of isolated domains of the elongation factor Tu from Thermus thermophilus HB8.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NMR study of the phosphate-binding elements of Escherichia coli elongation factor Tu catalytic domain.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Substitution of aspartic acid-80, a residue involved in coordination of magnesium, weakens the GTP binding and strongly enhances the GTPase of the G domain of elongation factor Tu
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Toward a model for the interaction between elongation factor Tu and the ribosome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Switching nucleotide specificity of Ha-Ras p21 by a single amino acid substitution at aspartate 119.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
GTPase activity of Rab5 acts as a timer for endocytic membrane fusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A GTPase distinct from Ran is involved in nuclear protein import
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aminoacyl transfer ribonucleic acid binding site of the bacterial elongation factor Tu
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct determination of the association constant between elongation factor Tu X GTP and aminoacyl-tRNA using fluorescence.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ternary complex of aminoacylated tRNA and EF-Tu-GTP. Recognition of a bond and a fold
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Minimalist aminoacylated RNAs as efficient substrates for elongation factor Tu
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mapping Escherichia coli elongation factor Tu residues involved in binding of aminoacyl-tRNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Histidine-118 of elongation factor Tu: its role in aminoacyl-tRNA binding and regulation of the GTPase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic engineering, isolation and characterization of a truncated Escherichia coli elongation factor Tu comprising domains 2 and 3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of the isolated domain II/III of Thermus thermophilus elongation factor Tu with the nucleotide exchange factor EF-Ts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The site of interaction of aminoacyl-tRNA with elongation factor Tu
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The GTPase activity of elongation factor Tu and the 3'-terminal end of aminoacyl-tRNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the conserved aspartate and phenylalanine residues in prokaryotic and mitochondrial elongation factor Ts in guanine nucleotide exchange
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of EF-Tu with EF-Ts: substitution of His-118 in EF-Tu destabilizes the EF-Tu x EF-Ts complex but does not prevent EF-Ts from stimulating the release of EF-Tu-bound GDP
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of cysteinyl residues in the activity of bacterial elongation factor Ts, a guanosine nucleotide dissociation protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The antibiotics kirromycin and pulvomycin bind to different sites on the elongation factor Tu from Escherichia coli
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antibiotics MDL 62,879 and kirromycin bind to distinct and independent sites of elongation factor Tu (EF-Tu).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations to kirromycin resistance occur in the interface of domains I and III of EF-Tu.GTP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cross-linking of tRNA at two different sites of the elongation factor Tu.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Substitution of Arg230 and Arg233 in Escherichia coli elongation factor Tu strongly enhances its pulvomycin resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel antibiotics, amythiamicins. IV. A mutation in the elongation factor Tu gene in a resistant mutant of B. subtilis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An elongation factor Tu (EF-Tu) resistant to the EF-Tu inhibitor GE2270 in the producing organism Planobispora rosea.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation, crystallization and X-ray analysis of the quaternary complex of Phe-tRNA(Phe), EF-Tu, a GTP analog and kirromycin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered regulation of the guanosine 5'-triphosphatase activity in a kirromycin-resistant elongation factor Tu
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutants of EF-Tu defective in binding aminoacyl-tRNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A comparative study of the 50S ribosomal subunit and several 50S subparticles in EF-T-and EF-G-dependent activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activity of the 30-S CsC1 Core in Elongation-Factor-Dependent GTP Hydrolysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ribosomal RNA and translation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for functional interaction between elongation factor Tu and 16S ribosomal RNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new model for the three-dimensional folding of Escherichia coli 16 S ribosomal RNA. II. The RNA-protein interaction data
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The 530 loop of 16S rRNA: a signal to EF-Tu?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Visualization of elongation factor Tu on the Escherichia coli ribosome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stepwise synthesis of a tripeptide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of the Inhibition of Protein Synthesis by Kirromycin. Role of Elongation Factor Tu and Ribosomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of split proteins from 30 S subunits in the ribosome-EF-T GTPase reaction.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular movement inside the translational engine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Studies on the binding of bacterial elongation factors EF Tu and EF G to ribosomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Further Evidence that Elongation Factor 1 Remains Bound to Ribosomes during Peptide Chain Elongation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How do the GTPases really work?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Substitution of histidine-84 and the GTPase mechanism of elongation factor Tu.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relevance of histidine-84 in the elongation factor Tu GTPase activity and in poly(Phe) synthesis: its substitution by glutamine and alanine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
On the mechanism of guanosine triphosphate hydrolysis in ras p21 proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Why have mutagenesis studies not located the general base in ras p21.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Substrate-assisted catalysis as a mechanism for GTP hydrolysis of p21ras and other GTP-binding proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras-catalyzed hydrolysis of GTP: a new perspective from model studies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NMR study of the phosphoryl binding loop in purine nucleotide proteins: evidence for strong hydrogen bonding in human N-ras p21.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of ions on the intrinsic activities of c-H-ras protein p21. A comparison with elongation factor Tu
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of GTP hydrolysis by p21N-ras catalyzed by GAP: studies with a fluorescent GTP analogue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Formation of a Transition-State Analog of the Ras GTPase Reaction by Ras GDP, Tetrafluoroaluminate, and GTPase-Activating Proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
GTPase mechanism of Gproteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hydrolysis of GTP by p21NRAS, the NRAS protooncogene product, is accompanied by a conformational change in the wild-type protein: use of a single fluorescent probe at the catalytic site
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is there a rate-limiting step before GTP cleavage by H-ras p21?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of elongation factor Tu with the ribosome. A study using the antibiotic kirromycin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ribosomes and translation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The allosteric three-site model for the ribosomal elongation cycle: features and future
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Why do two EF-Tu molecules act in the elongation cycle of protein biosynthesis?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Are the current three-site models valid descriptions of the ribosomal elongation cycle?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synergism between the GTPase activities of EF-Tu.GTP and EF-G.GTP on empty ribosomes. Elongation factors as stimulators of the ribosomal oscillation between two conformations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How many EF-Tu molecules participate in aminoacyl-tRNA binding and peptide bond formation in Escherichia coli translation?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A revised bacterial polypeptide chain elongation cycle with a stepwise increase in restriction of unwanted ternary complexes by the ribosome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stoichiometry for the elongation factor Tu.aminoacyl-tRNA complex switches with temperature.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two GTPs are consumed on EF-Tu per peptide bond in poly(Phe) synthesis, in spite of switching stoichiometry of the EF-Tu.aminoacyl-tRNA complex with temperature
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Elongation factor Tu D138N, a mutant with modified substrate specificity, as a tool to study energy consumption in protein biosynthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How many EF-Tu molecules participate in aminocyl-tRNA binding?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
GTP consumption of elongation factor Tu during translation of heteropolymeric mRNAs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
tRNA-ribosome interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Solution structure of the ternary complex between aminoacyl-tRNA, elongation factor Tu, and guanosine triphosphate.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stoichiometry of the EF-Tu.GTP complex with aminoacyl-tRNA: ternary of quinternary?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The elongation factor 3 unique in higher fungi and essential for protein biosynthesis is an E site factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extension of Watson's model for the elongation cycle of protein biosynthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The "allosteric three-site model" of elongation cannot be confirmed in a well-defined ribosome system from Escherichia coli
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ribosomal proteins of Escherichia coli localization and possible molecular mechanism in translation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Renaturation of rhodanese by translational elongation factor (EF) Tu. Protein refolding by EF-Tu flexing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chaperone properties of bacterial elongation factor EF-Tu
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https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
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Escherichia coli trigger factor is a prolyl isomerase that associates with nascent polypeptide chains.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
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SETOR: hardware-lighted three-dimensional solid model representations of macromolecules
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stated in
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reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900169-9
retrieved
7 January 2021
based on heuristic
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Identifiers
DOI
10.1016/S0167-4781(98)00169-9
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PubMed ID
9838020
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