(Q28290823)

English

Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study

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Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study (English)

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relapsing-remitting multiple sclerosis

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multiple sclerosis

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inferred from title

Cris Constantinescu

2

object named as

Cris S Constantinescu

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author name string

Benjamin M Segal

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Aparna Raychaudhuri

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Lilianne Kim

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Rosanne Fidelus-Gort

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Lloyd H Kasper

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language of work or name

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publication date

September 2008

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Lancet Neurology

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7

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796-804

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9

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Immunological aspects of experimental allergic encephalomyelitis and multiple sclerosis

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A controlled trial of natalizumab for relapsing multiple sclerosis.

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Mechanism of action of glatiramer acetate in treatment of multiple sclerosis

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Randomised double-blind placebo-controlled study of interferon β-1a in relapsing/remitting multiple sclerosis

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Mitoxantrone for multiple sclerosis causing acute lymphoblastic leukemia.

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Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial. The Copolymer 1 Multiple Sclerosis Study Group

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Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis

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Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

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An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease.

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IL-12 unmasks latent autoimmune disease in resistant mice

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Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

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Interleukin-12: a proinflammatory cytokine with immunoregulatory functions

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The IL-23/Th(17) axis: therapeutic targets for autoimmune inflammation

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Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions

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Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia.

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Increased interleukin 12 production in progressive multiple sclerosis: induction by activated CD4+ T cells via CD40 ligand

1 reference

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IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production

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Prevention of experimental autoimmune encephalomyelitis in common marmosets using an anti-IL-12p40 monoclonal antibody.

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Activation of APCs through CD40 or Toll-like receptor 9 overcomes tolerance and precipitates autoimmune disease

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Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

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Cytokine mRNA expression in inflammatory multiple sclerosis lesions: detection by non-radioactive in situ hybridization

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Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis

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IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

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IL-12 dependent/IFN gamma independent expression of CCR5 by myelin-reactive T cells correlates with encephalitogenicity

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Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system

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Suppression of ongoing disease in a nonhuman primate model of multiple sclerosis by a human-anti-human IL-12p40 antibody

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1 reference

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1 reference

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1 reference

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7 January 2021

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

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1 reference

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1 reference

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1 reference

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Identifiers

10.1016/S1474-4422(08)70173-X

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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