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Klotho: an antiaging protein involved in mineral and vitamin D metabolism
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scholarly article
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review article
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title
Klotho: an antiaging protein involved in mineral and vitamin D metabolism
(English)
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main subject
vitamin D
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vitamin
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author
Laurent Beck
object named as
L Beck
series ordinal
4
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Gérard Friedlander
object named as
G Friedlander
series ordinal
6
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author name string
P-Ureña Torres
series ordinal
1
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D Prié
series ordinal
2
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V Molina-Blétry
series ordinal
3
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C Silve
series ordinal
5
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language of work or name
English
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publication date
April 2007
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published in
Kidney International
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volume
71
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issue
8
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page(s)
730-7
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cites work
Mutation of the mouse klotho gene leads to a syndrome resembling ageing
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of aging in mice by the hormone Klotho
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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inferred from DOI database lookup
The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of fibroblast growth factor-23 signaling by klotho
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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inferred from DOI database lookup
Klotho is a novel beta-glucuronidase capable of hydrolyzing steroid beta-glucuronides
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence, structural, functional, and phylogenetic analyses of three glycosidase families
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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Immunohistochemical localization of Klotho protein in brain, kidney, and reproductive organs of mice.
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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Expression of Klotho protein in the inner ear.
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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Klotho protein activates the PKC pathway in the kidney and testis and suppresses 25-hydroxyvitamin D3 1alpha-hydroxylase gene expression.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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Regulation of oxidative stress by the anti-aging hormone klotho
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Klotho converts canonical FGF receptor into a specific receptor for FGF23
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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Severely reduced production of klotho in human chronic renal failure kidney.
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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Modulation of gene expression by moxonidine in rats with chronic renal failure
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
retrieved
7 January 2021
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inferred from DOI database lookup
Klotho reduces apoptosis in experimental ischaemic acute renal failure
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
retrieved
7 January 2021
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inferred from DOI database lookup
Downregulation of the Klotho gene in the kidney under sustained circulatory stress in rats
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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inferred from DOI database lookup
Molecular cloning and expression of a novel klotho-related protein
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
retrieved
7 January 2021
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inferred from DOI database lookup
In vivo klotho gene transfer ameliorates angiotensin II-induced renal damage
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
retrieved
7 January 2021
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inferred from DOI database lookup
Oxidative stress decreases klotho expression in a mouse kidney cell line.
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Klotho protein promotes adipocyte differentiation
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
retrieved
7 January 2021
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Klotho gene variation and expression in 20 inbred mouse strains.
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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[Ageing, genetics and the somatotropic axis]
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anti-apoptotic and anti-senescence effects of Klotho on vascular endothelial cells
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
retrieved
7 January 2021
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inferred from DOI database lookup
In vivo klotho gene delivery protects against endothelial dysfunction in multiple risk factor syndrome
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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Klotho protein protects against endothelial dysfunction
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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Klotho-induced insulin resistance: a blessing in disguise?
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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inferred from DOI database lookup
Association of human aging with a functional variant of klotho
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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inferred from DOI database lookup
Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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Cellular and molecular mechanism of low-turnover osteopenia in the klotho-deficient mouse.
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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Klotho gene polymorphisms associated with bone density of aged postmenopausal women
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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Association of klotho gene polymorphism with bone density and spondylosis of the lumbar spine in postmenopausal women
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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The progression of aging in klotho mutant mice can be modified by dietary phosphorus and zinc
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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inferred from DOI database lookup
Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
retrieved
7 January 2021
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inferred from DOI database lookup
Hypervitaminosis D and premature aging: lessons learned from Fgf23 and Klotho mutant mice
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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inferred from DOI database lookup
Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated process
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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inferred from DOI database lookup
Defect in parathyroid-hormone-induced luminal calcium absorption in connecting tubules of Klotho mice.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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The epithelial Ca2+ channel TRPV5 is essential for proper osteoclastic bone resorption
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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inferred from DOI database lookup
Correlation between hyperphosphatemia and type II Na-Pi cotransporter activity in klotho mice
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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inferred from DOI database lookup
Regulation of stanniocalcin 1 and 2 expression in the kidney by klotho gene
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
retrieved
7 January 2021
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inferred from DOI database lookup
Iron chelation and a free radical scavenger suppress angiotensin II-induced downregulation of klotho, an anti-aging gene, in rat.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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inferred from DOI database lookup
Molecular cloning of rat klotho cDNA: markedly decreased expression of klotho by acute inflammatory stress
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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HMG-CoA reductase inhibitors up-regulate anti-aging klotho mRNA via RhoA inactivation in IMCD3 cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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Upregulation of the klotho gene expression by thyroid hormone and during adipose differentiation in 3T3-L1 adipocytes
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.KI.5002163
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7 January 2021
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Identifiers
DOI
10.1038/SJ.KI.5002163
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Dimensions Publication ID
1047402132
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Fatcat ID
release_ijhmidvoobgodg2kbgzhypbh7m
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PubMed publication ID
17332731
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ResearchGate publication ID
6473454
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