(Q28291653)

1

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Tanja Schulz-Gasch

2

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Brigitte D'Arcy

3

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Jörg Benz

4

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Johannes Aebi

5

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Henrietta Dehmlow

6

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Michael Hennig

7

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Martine Stihle

8

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Armin Ruf

Structure and function of a squalene cyclase

9

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language of work or name

English

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publication date

4 November 2004

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published in

Nature

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volume

432

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issue

7013

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page(s)

118-22

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cites work

1 reference

The monotopic membrane protein human oxidosqualene cyclase is active as monomer

20 April 2017

1 reference

The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase

20 April 2017

1 reference

The structure of the membrane protein squalene-hopene cyclase at 2.0 A resolution

20 April 2017

1 reference

Studies on the Substrate Binding Segments and Catalytic Action of Lanosterol Synthase. Affinity Labeling with Carbocations Derived from Mechanism-Based Analogs of 2,3-Oxidosqualene and Site-Directed Mutagenesis Probes

20 April 2017

1 reference

Crystal structure of a squalene cyclase in complex with the potential anticholesteremic drug Ro48-8071

20 April 2017

1 reference

Efficient anisotropic refinement of macromolecular structures using FFT

20 April 2017

1 reference

Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

MOLREP: an Automated Program for Molecular Replacement

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

Enzyme Mechanisms for Polycyclic Triterpene Formation

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

7 January 2021

Squalene-hopene cyclase: catalytic mechanism and substrate recognition

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

7 January 2021

A specific amino acid repeat in squalene and oxidosqualene cyclases

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

7 January 2021

Intracellular protein topogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

7 January 2021

Thiol-modifying inhibitors for understanding squalene cyclase function

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

7 January 2021

Molecular cloning of a Schizosaccharomyces pombe cDNA encoding lanosterol synthase and investigation of conserved tryptophan residues

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

7 January 2021

Cation-pi interactions in structural biology

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

7 January 2021

Mechanistic insights into oxidosqualene cyclizations through homology modeling

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

7 January 2021

Conversion of squalene to the pentacarbocyclic hopene

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

7 January 2021

Methodology for the Preparation of Pure RecombinantS. cerevisiaeLanosterol Synthase Using a Baculovirus Expression System. Evidence That Oxirane Cleavage and A-Ring Formation Are Concerted in the Biosynthesis of Lanosterol from 2,3-Oxidosqualene

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

7 January 2021

Photoaffinity labeling of oxidosqualene cyclase and squalene cyclase by a benzophenone-containing inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

7 January 2021

Quinuclidine inhibitors of 2,3-oxidosqualene cyclase-lanosterol synthase: optimization from lipid profiles

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

7 January 2021

Synthesis and structure-activity studies of novel orally active non-terpenoic 2,3-oxidosqualene cyclase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

7 January 2021

ARP/wARP's model-building algorithms. I. The main chain

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

7 January 2021

Modelling prior distributions of atoms for macromolecular refinement and completion.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02993

7 January 2021