(Q28296660)

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NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex

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NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex (English)

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5

object named as

Thomas Benzing

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author name string

Eun Young Kim

1

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Marc Anderson

2

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Cory Wilson

3

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Henning Hagmann

4

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Stuart E Dryer

6

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language of work or name

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publication date

1 November 2013

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American Journal of Physiology - Cell Physiology

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305

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9

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C960-71

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Opposing effects of podocin on the gating of podocyte TRPC6 channels evoked by membrane stretch or diacylglycerol

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Acid sensing ionic channels: modulation by redox reagents.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Effects of NADPH oxidase inhibitor in diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

A stomatin dimer modulates the activity of acid-sensing ion channels

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

ASIC1a-specific modulation of acid-sensing ion channels in mouse cortical neurons by redox reagents

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

ASIC-like currents in freshly isolated cerebral artery smooth muscle cells are inhibited by endogenous oxidase activity

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

The calcium channel alpha2delta-2 subunit partitions with CaV2.1 into lipid rafts in cerebellum: implications for localization and function.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Stomatin immunoreactivity in ciliated cells of the human airway epithelium

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Lectin-induced activation of plasma membrane NADPH oxidase in cholesterol-depleted human neutrophils.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCgamma2 signaling axis in mice

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Canonical transient receptor potential 6 (TRPC6), a redox-regulated cation channel

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Interleukin-8-induced priming of neutrophil oxidative burst requires sequential recruitment of NADPH oxidase components into lipid rafts

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

A novel TRPC6 mutation that causes childhood FSGS.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Molecular basis of the functional podocin-nephrin complex: mutations in the NPHS2 gene disrupt nephrin targeting to lipid raft microdomains

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Synergistic activation of vascular TRPC6 channel by receptor and mechanical stimulation via phospholipase C/diacylglycerol and phospholipase A2/omega-hydroxylase/20-HETE pathways

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Polyphenols restore endothelial function in DOCA-salt hypertension: role of endothelin-1 and NADPH oxidase.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Inhibition of NADPH oxidase activation in endothelial cells by ortho-methoxy-substituted catechols

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Insulin increases surface expression of TRPC6 channels in podocytes: role of NADPH oxidases and reactive oxygen species

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Sustained activation of N-methyl-D-aspartate receptors in podoctyes leads to oxidative stress, mobilization of transient receptor potential canonical 6 channels, nuclear factor of activated T cells activation, and apoptotic cell death

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Neph1 regulates steady-state surface expression of Slo1 Ca(2+)-activated K(+) channels: different effects in embryonic neurons and podocytes

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Nephrin binds to the COOH terminus of a large-conductance Ca2+-activated K+ channel isoform and regulates its expression on the cell surface

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Podocyte-specific overexpression of wild type or mutant trpc6 in mice is sufficient to cause glomerular disease

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

The podocyte's response to stress: the enigma of foot process effacement

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Listeriolysin O suppresses phospholipase C-mediated activation of the microbicidal NADPH oxidase to promote Listeria monocytogenes infection

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

High glucose induces podocyte apoptosis by stimulating TRPC6 via elevation of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Analysis of cholesterol trafficking with fluorescent probes

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Regulation of intracellular signalling through cysteine oxidation by reactive oxygen species

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Podocin inactivation in mature kidneys causes focal segmental glomerulosclerosis and nephrotic syndrome

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Inhomogeneous distribution of filipin-sterol complexes in smooth muscle cell plasma membrane

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Flotillins and the PHB domain protein family: rafts, worms and anaesthetics

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Cell biology of the glomerular podocyte

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Regulation of NADPH oxidase in vascular endothelium: the role of phospholipases, protein kinases, and cytoskeletal proteins

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Stomatin modulates gating of acid-sensing ion channels

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Podocin localizes in the kidney to the slit diaphragm area

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Stomatin interacts with GLUT1/SLC2A1, band 3/SLC4A1, and aquaporin-1 in human erythrocyte membrane domains.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Lipid rafts determine efficiency of NADPH oxidase activation in neutrophils

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Podocyte process effacement in vivo

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Apocynin: molecular aptitudes

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

G protein-mediated stretch reception

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Preservation of kidney function with combined inhibition of NADPH oxidase and angiotensin-converting enzyme in diabetic nephropathy.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

NADPH oxidase contributes to renal damage and dysfunction in Dahl salt-sensitive hypertension.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Cell-free translocation of recombinant p47-phox, a component of the neutrophil NADPH oxidase: effects of guanosine 5'-O-(3-thiotriphosphate), diacylglycerol, and an anionic amphiphile

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Phospholipase D-mediated activation of IQGAP1 through Rac1 regulates hyperoxia-induced p47phox translocation and reactive oxygen species generation in lung endothelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

The phagocyte NADPH oxidase depends on cholesterol-enriched membrane microdomains for assembly

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

NADPH oxidase-derived ROS contributes to upregulation of TRPC6 expression in puromycin aminonucleoside-induced podocyte injury

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Effects of tempol and redox-cycling nitroxides in models of oxidative stress

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Comparative pharmacology of chemically distinct NADPH oxidase inhibitors

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

ANG II promotes autophagy in podocytes

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Stomatin inhibits pannexin-1-mediated whole-cell currents by interacting with its carboxyl terminal

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

Use of cyclodextrins to manipulate plasma membrane cholesterol content: evidence, misconceptions and control strategies

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00191.2013

21 January 2018

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