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Introducing genetically encoded aldehydes into proteins

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Introducing genetically encoded aldehydes into proteins (English)

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3

Carolyn R Bertozzi

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Isaac S Carrico

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1

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Brian L Carlson

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2

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language of work or name

English

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publication date

June 2007

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published in

Nature Chemical Biology

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volume

3

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issue

6

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page(s)

321-2

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cites work

A novel amino acid modification in sulfatases that is defective in multiple sulfatase deficiency

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The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases

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Multiple sulfatase deficiency is caused by mutations in the gene encoding the human C(alpha)-formylglycine generating enzyme

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Specific covalent labeling of recombinant protein molecules inside live cells

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Expanding the genetic code

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Sequence determinants directing conversion of cysteine to formylglycine in eukaryotic sulfatases

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The human SUMF1 gene, required for posttranslational sulfatase modification, defines a new gene family which is conserved from pro- to eukaryotes

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N-terminal protein modification through a biomimetic transamination reaction.

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Non-canonical amino acids in protein engineering

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Site-specific labeling of cell surface proteins with biophysical probes using biotin ligase

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In vivo reporter labeling of proteins via metabolic delivery of coenzyme A analogues.

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Specific labeling of cell surface proteins with chemically diverse compounds

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Labeling proteins with small molecules by site-specific posttranslational modification.

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Posttranslational formation of formylglycine in prokaryotic sulfatases by modification of either cysteine or serine

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Effect of pegylation on pharmaceuticals

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Identifiers

DOI

10.1038/NCHEMBIO878

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3566166

OpenCitations bibliographic resource ID

3566166

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stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3566166

PubMed publication ID

17450134

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stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3566166

(Q28298867)

Introducing genetically encoded aldehydes into proteins

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