(Q28303208)

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Altered neuronal mitochondrial coenzyme A synthesis in neurodegeneration with brain iron accumulation caused by abnormal processing, stability, and catalytic activity of mutant pantothenate kinase 2

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15659606%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Altered neuronal mitochondrial coenzyme A synthesis in neurodegeneration with brain iron accumulation caused by abnormal processing, stability, and catalytic activity of mutant pantothenate kinase 2 (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15659606%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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neurodegeneration with brain iron accumulation

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John Q. Trojanowski

3

object named as

John Q Trojanowski

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7 January 2020

author name string

Paul T Kotzbauer

1

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7 January 2020

Adam C Truax

2

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7 January 2020

Virginia M-Y Lee

4

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7 January 2020

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publication date

1 January 2005

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7 January 2020

Journal of Neuroscience

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7 January 2020

25

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7 January 2020

3

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7 January 2020

689-698

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7 January 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6725318/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Yeast and human frataxin are processed to mature form in two sequential steps by the mitochondrial processing peptidase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Widespread occurrence of alpha-synuclein/NACP-immunoreactive neuronal inclusions in juvenile and adult-onset Hallervorden-Spatz disease with Lewy bodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pantothenate kinase regulation of the intracellular concentration of coenzyme A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Juvenile-onset generalized neuroaxonal dystrophy (Hallervorden-Spatz disease) with diffuse neurofibrillary and lewy body pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegeneration with brain iron accumulation, type 1 is characterized by alpha-, beta-, and gamma-synuclein neuropathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Widespread expression of alpha-synuclein and tau immunoreactivity in Hallervorden-Spatz syndrome with protracted clinical course

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical and biochemical studies demonstrate a distinct profile of alpha-synuclein permutations in multiple system atrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two-step processing of human frataxin by mitochondrial processing peptidase. Precursor and intermediate forms are cleaved at different rates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-synuclein accumulation in a case of neurodegeneration with brain iron accumulation type 1 (NBIA-1, formerly Hallervorden-Spatz syndrome) with widespread cortical and brainstem-type Lewy bodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biosynthesis of coenzyme A in bacteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent advances in disorders of iron metabolism: mutations, mechanisms and modifiers

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HARP syndrome is allelic with pantothenate kinase-associated neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The murine pantothenate kinase (Pank1) gene encodes two differentially regulated pantothenate kinase isozymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial processing peptidases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytic deformity and globular structures are characteristic of the brains of patients with aceruloplasminemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic, clinical, and radiographic delineation of Hallervorden-Spatz syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron metabolism and mitochondrial abnormalities in Friedreich ataxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An isoform of hPANK2, deficient in pantothenate kinase-associated neurodegeneration, localizes to mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic systemic complex I inhibition induces a hypokinetic multisystem degeneration in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning, expression, characterization, and interaction of two components of a human mitochondrial fatty acid synthase. Malonyltransferase and acyl carrier protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compound heterozygous PANK2 mutations confirm HARP and Hallervorden-Spatz syndromes are allelic

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathological aspects of mitochondrial DNA disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibrillization of alpha-synuclein and tau in familial Parkinson's disease caused by the A53T alpha-synuclein mutation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain, skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration (HARP syndrome)

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The acyl-carrier protein in Neurospora crassa mitochondria is a subunit of NADH: ubiquinone reductase (complex I)

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hallervorden-Spatz Syndrome and Brain Iron Metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial oxidative phosphorylation defects in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial complex I deficiency in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormalities of the electron transport chain in idiopathic Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MITOCHONDRIAL FUNCTION IN PARKINSON'S DISEASE

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and sequence-specific proteolysis of hybrid proteins produced in Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hallervorden-Spatz syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Standardization of various applications of methacrylate embedding and silver methenamine for light and electron microscopy immunocytochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of coenzyme A biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acanthocytosis, retinitis pigmentosa, and pallidal degeneration: a report of three patients, including the second reported case with hypoprebetalipoproteinemia (HARP syndrome)

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics and regulation of pantothenate kinase from Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial respiratory chain activity in skeletal muscle from patients with Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrastructure and immunoreactivity of dystrophic axons indicate a different pathogenesis of Hallervorden-Spatz disease and infantile neuroaxonal dystrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different respiratory-defective phenotypes of Neurospora crassa and Saccharomyces cerevisiae after inactivation of the gene encoding the mitochondrial acyl carrier protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nosology of Hallervorden-spatz disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Computational method to predict mitochondrially imported proteins and their targeting sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial fatty acid synthesis: a relic of endosymbiontic origin and a specialized means for respiration

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maturation of wild-type and mutated frataxin by the mitochondrial processing peptidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15659606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.4265-04.2005

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15659606%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15659606%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15659606%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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