(Q28304385)

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gp160 of HIV or anti-CD4 monoclonal antibody ligation of CD4 induces inhibition of JNK and ERK-2 activities in human peripheral CD4+ T lymphocytes

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scholarly article

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gp160 of HIV or anti-CD4 monoclonal antibody ligation of CD4 induces inhibition of JNK and ERK-2 activities in human peripheral CD4+ T lymphocytes (English)

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monoclonal antibody

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4

object named as

A Fischer

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author name string

N Jabado

1

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A Pallier

2

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S Jauliac

3

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C Hivroz

5

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language of work or name

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publication date

February 1997

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European Journal of Immunology

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27

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2

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397-404

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Signal transduction by tumor necrosis factor mediated by JNK protein kinases

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Interaction between CD4 and class II MHC molecules mediates cell adhesion

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Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen

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Effective activation of resting mouse T lymphocytes by cross-linking submitogenic concentrations of the T cell antigen receptor with either Lyt-2 or L3T4

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The role of the L3T4 molecule in mitogen and antigen-activated signal transduction

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T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

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The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

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Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

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Binding of HTLV-III/LAV to T4+ T cells by a complex of the 110K viral protein and the T4 molecule

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Shedding and interspecies type sero-reactivity of the envelope glycopolypeptide gp120 of the human immunodeficiency virus

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Perturbation of the T4 molecule transmits a negative signal to T cells

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Signal transduction through CD4 receptors: stimulatory vs. inhibitory activity is regulated by CD4 proximity to the CD3/T cell receptor

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Interaction of HIV gp120 and anti-CD4 antibodies with the CD4 molecule on human CD4+ T cells inhibits the binding activity of NF-AT, NF-kappa B and AP-1, three nuclear factors regulating interleukin-2 gene enhancer activity

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Transmission of signals from the T lymphocyte antigen receptor to the genes responsible for cell proliferation and immune function: the missing link

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Signal transduction by lymphocyte antigen receptors

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NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes

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Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function.

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Transactivation by AP-1 is a molecular target of T cell clonal anergy

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The serum response element

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Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain

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Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

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Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter

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The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

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Mitogen-activated protein kinase cascades and regulation of gene expression

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The B7 and CD28 receptor families

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Signaling requirements for the expression of the transactivating factor NF-AT in human T lymphocytes

1 reference

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JNK is involved in signal integration during costimulation of T lymphocytes.

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p21ras couples the T cell antigen receptor to extracellular signal-regulated kinase 2 in T lymphocytes.

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Stimulation of p21 ras upon T-cell activation

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The regulation and function of p21ras in T cells

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p21ras mediates control of IL-2 gene promoter function in T cell activation.

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Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

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The mitogen-activated protein kinase activator

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Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

1 reference

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Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

1 reference

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Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

1 reference

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The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product

1 reference

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The MEK kinase activity of the catalytic domain of RAF-1 is regulated independently of Ras binding in T cells

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Blocked Ras activation in anergic CD4+ T cells

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Regulatory mechanisms for ras proteins

1 reference

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Control of memory CD4 T cell activation: MHC class II molecules on APCs and CD4 ligation inhibit memory but not naive CD4 T cells

1 reference

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Inhibition of T cell receptor expression and function in immature CD4+CD8+ cells by CD4

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1 reference

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Synergism between HIV gp120 and gp120-specific antibody in blocking human T cell activation

1 reference

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Role of CD4 molecule in the induction of interleukin 2 and interleukin 2 receptor in class II major histocompatibility complex-restricted antigen-specific T helper clones. T cell receptor/CD3 complex transmits CD4-dependent and CD4-independent signa

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Human immunodeficiency virus-1 glycoproteins gp120 and gp160 specifically inhibit the CD3/T cell-antigen receptor phosphoinositide transduction pathway

1 reference

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Requirement for association of p56lck with CD4 in antigen-specific signal transduction in T cells

1 reference

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Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck

1 reference

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7 January 2021

based on heuristic

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Human immunodeficiency virus gp120 and derived peptides activate protein tyrosine kinase p56lck in human CD4 T lymphocytes

1 reference

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7 January 2021

based on heuristic

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Interaction of human immunodeficiency virus glycoprotein 160 with CD4 in Jurkat cells increases p56lck autophosphorylation and kinase activity

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

HIV-1 glycoprotein gp120 disrupts CD4-p56lck/CD3-T cell receptor interactions and inhibits CD3 signaling.

1 reference

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Association of tyrosine kinase p56lck with CD4 inhibits the induction of growth through the alpha beta T-cell receptor

1 reference

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1 reference

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based on heuristic

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10.1002/EJI.1830270209

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release_edxavuam5zfwpprtvzi4qa777e

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