(Q28307965)

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Activation of the heat shock response in a primary cellular model of motoneuron neurodegeneration-evidence for neuroprotective and neurotoxic effects

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Activation of the heat shock response in a primary cellular model of motoneuron neurodegeneration-evidence for neuroprotective and neurotoxic effects (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275696&resulttype=core&format=json

13 May 2020

1 reference

based on heuristic

inferred from title

neurodegeneration

1 reference

based on heuristic

inferred from title

author name string

Bernadett Kalmar

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275696&resulttype=core&format=json

13 May 2020

Linda Greensmith

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275696&resulttype=core&format=json

13 May 2020

language of work or name

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publication date

2009

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Cellular & Molecular Biology Letters

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275696&resulttype=core&format=json

13 May 2020

14

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275696&resulttype=core&format=json

13 May 2020

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275696&resulttype=core&format=json

13 May 2020

319-335

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275696&resulttype=core&format=json

13 May 2020

Bimoclomol: a nontoxic, hydroxylamine derivative with stress protein-inducing activity and cytoprotective effects

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Characterization of the caspase cascade in a cell culture model of SOD1-related familial amyotrophic lateral sclerosis: expression, activation and therapeutic effects of inhibition.

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Apoptosis Induction in HL-60 Cells and Inhibition of Topoisomerase II by Triterpene Celastrol

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Oxidative neurotoxicity in rat cerebral cortex neurons: Synergistic effects of H2O2 and NO on apoptosis involving activation of p38 mitogen‐activated protein kinase and caspase‐3

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Activation of the p38MAPK cascade is associated with upregulation of TNF alpha receptors in the spinal motor neurons of mouse models of familial ALS.

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis.

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Exogenous delivery of heat shock protein 70 increases lifespan in a mouse model of amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Stress management - heat shock protein-70 and the regulation of apoptosis

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Inter- and intracellular signaling in amyotrophic lateral sclerosis: role of p38 mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Role of heat shock response and Hsp27 in mutant SOD1-dependent cell death.

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Decrease of Hsp25 protein expression precedes degeneration of motoneurons in ALS-SOD1 mice

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70.

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule.

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Induction of heat shock proteins in differentiated human and rodent neurons by celastrol

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Heat shock proteins increase resistance to apoptosis.

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Elevation of the Hsp70 chaperone does not effect toxicity in mouse models of familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Upregulation of heat shock proteins rescues motoneurones from axotomy-induced cell death in neonatal rats

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Mutant dynactin in motor neuron disease.

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Major stress protein Hsp70 interacts with NF-kB regulatory complex in human T-lymphoma cells

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Celastrols as inducers of the heat shock response and cytoprotection.

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Reversal of a full-length mutant huntingtin neuronal cell phenotype by chemical inhibitors of polyglutamine-mediated aggregation

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Celastrol protects against MPTP- and 3-nitropropionic acid-induced neurotoxicity.

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Celastrol inhibits polyglutamine aggregation and toxicity though induction of the heat shock response

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Hsp27 and Hsp70 administered in combination have a potent protective effect against FALS-associated SOD1-mutant-induced cell death in mammalian neuronal cells

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Inhibition of NF-κB activation through targeting IκB kinase by celastrol, a quinone methide triterpenoid

1 reference

https://api.crossref.org/works/10.2478%2FS11658-009-0002-8

21 January 2018

Fast axonal transport in amyotrophic lateral sclerosis: an intra-axonal organelle traffic analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19183864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Celastrol blocks neuronal cell death and extends life in transgenic mouse model of amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19183864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitin and heat shock protein expression in amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19183864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiinflammatory constituents of Celastrus orbiculatus inhibit the NF-kappaB activation and NO production

1 reference

https://pubmed.ncbi.nlm.nih.gov/19183864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19183864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyotrophic lateral sclerosis: a proposed mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19183864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High threshold for induction of the stress response in motor neurons is associated with failure to activate HSF1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19183864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid purification of embryonic rat motoneurons: an in vitro model for studying MND/ALS pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19183864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysregulation of stathmin, a microtubule-destabilizing protein, and up-regulation of Hsp25, Hsp27, and the antioxidant peroxiredoxin 6 in a mouse model of familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19183864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Staurosporine-induced apoptosis of cultured rat hippocampal neurons involves caspase-1-like proteases as upstream initiators and increased production of superoxide as a main downstream effector.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19183864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calpain-mediated androgen receptor breakdown in apoptotic prostate cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19183864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bimoclomol, a heat shock protein co-inducer, acts by the prolonged activation of heat shock factor-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19183864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of HSP27 in a Transgenic Model of ALS

1 reference

https://pubmed.ncbi.nlm.nih.gov/19183864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of neonatal nerve injury on the expression of heat shock proteins in developing rat motoneurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/19183864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the AMPA-activated receptors present on motoneurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/19183864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2478/S11658-009-0002-8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275696&resulttype=core&format=json

13 May 2020

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.2478/s11658-009-0002-8

release_fr4qrz5hejhfzh5zhoxm7qd24q

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275696&resulttype=core&format=json

13 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275696&resulttype=core&format=json

13 May 2020

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