Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q28343672)
Watch
English
Polycitone A, a novel and potent general inhibitor of retroviral reverse transcriptases and cellular DNA polymerases
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
1220617
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10548537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
title
Polycitone A, a novel and potent general inhibitor of retroviral reverse transcriptases and cellular DNA polymerases
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
1220617
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10548537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
main subject
3,4-Bis(3,5-dibromo-4-hydroxyphenyl)-1-[2-(4-hydroxyphenyl)ethyl]-3-pyrroline-2,5-dione
1 reference
inferred from
reverse claim
Polycitone A
1 reference
inferred from
reverse claim
Polycitor
1 reference
inferred from
reverse claim
author name string
Loya S
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
1220617
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10548537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
Rudi A
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
1220617
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10548537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
Kashman Y
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
1220617
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10548537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
Hizi A
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
1220617
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10548537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
language of work or name
English
0 references
publication date
1 November 1999
1 reference
stated in
Europe PubMed Central
PMC publication ID
1220617
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10548537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
full work available at URL
https://europepmc.org/articles/pmc1220617?pdf=render
1 reference
stated in
Unpaywall
retrieved
19 March 2024
reference URL
https://api.unpaywall.org/v2/10.1042/bj3440085?email=unpaywall_01@example.com
published in
Biochemical Journal
1 reference
stated in
Europe PubMed Central
PMC publication ID
1220617
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10548537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
volume
344 Pt 1
1 reference
stated in
Europe PubMed Central
PMC publication ID
1220617
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10548537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
issue
1
1 reference
reference URL
http://api.crossref.org/works/10.1042%2Fbj3440085
page(s)
85-92
1 reference
stated in
Europe PubMed Central
PMC publication ID
1220617
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10548537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
online access status
open access
1 reference
stated in
Unpaywall
retrieved
19 March 2024
reference URL
https://api.unpaywall.org/v2/10.1042/bj3440085?email=unpaywall_01@example.com
access restriction status
open access
1 reference
based on heuristic
inferred from online access status
cites work
Mode of inhibition of HIV reverse transcriptase by 2-hexaprenylhydroquinone, a novel general inhibitor of RNA-and DNA-directed DNA polymerases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
20 March 2017
Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
20 March 2017
Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
20 March 2017
2.3 A crystal structure of the catalytic domain of DNA polymerase beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
20 March 2017
Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
20 March 2017
Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
20 March 2017
Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
20 March 2017
Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
20 March 2017
Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
20 March 2017
HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
20 March 2017
Illimaquinone, a selective inhibitor of the RNase H activity of human immunodeficiency virus type 1 reverse transcriptase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
20 March 2017
An antiviral target on reverse transcriptase of human immunodeficiency virus type 1 revealed by tetrahydroimidazo-[4,5,1-jk] [1,4]benzodiazepin-2 (1H)-one and -thione derivatives
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
20 March 2017
Human immunodeficiency virus reverse transcriptase. Substrate and inhibitor kinetics with thymidine 5'-triphosphate and 3'-azido-3'-deoxythymidine 5'-triphosphate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
20 March 2017
The inhibition of human immunodeficiency virus type 1 reverse transcriptase by avarol and avarone derivatives
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
20 March 2017
Kinetics of inhibition of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase by the novel HIV-1-specific nucleoside analogue [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5 "- (4"-amino-1",2"-oxathiole-2",2"-di
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
20 March 2017
The carotenoid halocynthiaxanthin: a novel inhibitor of the reverse transcriptases of human immunodeficiency viruses type 1 and type 2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
20 March 2017
Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
7 April 2017
Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
7 April 2017
Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
7 April 2017
The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
7 April 2017
The processivity of DNA synthesis exhibited by drug-resistant variants of human immunodeficiency virus type-1 reverse transcriptase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
29 September 2017
Analysis of HIV-2 RT mutants provides evidence that resistance of HIV-1 RT and HIV-2 RT to nucleoside analogs involves a repositioning of the template-primer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
29 September 2017
Targeting HIV reverse transcriptase for anti-AIDS drug design: structural and biological considerations for chemotherapeutic strategies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
29 September 2017
Structural and mechanistic relationships between nucleic acid polymerases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
29 September 2017
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) for the treatment of human immunodeficiency virus type 1 (HIV-1) infections: strategies to overcome drug resistance development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
29 September 2017
Antiviral therapy for human immunodeficiency virus infections
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
29 September 2017
Insights into DNA polymerization mechanisms from structure and function analysis of HIV-1 reverse transcriptase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
29 September 2017
Peyssonols A and B, two novel inhibitors of the reverse transcriptases of human immunodeficiency virus types 1 and 2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
29 September 2017
Function and structure relationships in DNA polymerases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
29 September 2017
Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
29 September 2017
Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
29 September 2017
Prolonged zidovudine therapy in patients with AIDS and advanced AIDS-related complex. AZT Collaborative Working Group
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
29 September 2017
Expression of soluble, enzymatically active, human immunodeficiency virus reverse transcriptase in Escherichia coli and analysis of mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
29 September 2017
Human immunodeficiency virus reverse transcriptase: steady-state and pre-steady-state kinetics of nucleotide incorporation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
29 September 2017
HIV inhibitors targeted at the reverse transcriptase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
29 September 2017
Selective and synergistic inhibition of human immunodeficiency virus type 1 reverse transcriptase by a non-nucleoside inhibitor, MKC-442.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
2 June 2018
Kinetic mechanism of the DNA-dependent DNA polymerase activity of human immunodeficiency virus reverse transcriptase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
2 June 2018
Mechanism of inhibition of HIV reverse transcriptase by toxiusol, a novel general inhibitor of retroviral and cellular DNA polymerases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
2 June 2018
3,5,8-Trihydroxy-4-quinolone, a novel natural inhibitor of the reverse transcriptases of human immunodeficiency viruses type 1 and type 2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
2 June 2018
The DNA-Dependent and RNA-Dependent DNA Polymerase Activities of the Reverse Transcriptases of Human Immunodeficiency Viruses Types 1 and 2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
2 June 2018
Catalytic properties of the reverse transcriptases of human immunodeficiency viruses type 1 and type 2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
2 June 2018
Fidelity of the RNA-dependent DNA synthesis exhibited by the reverse transcriptases of human immunodeficiency virus types 1 and 2 and of murine leukemia virus: mispair extension frequencies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
2 June 2018
HIV-1 reverse transcriptase purified from a recombinant strain of Escherichia coli.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
2 June 2018
Mechanism of inhibition of HIV-1 reverse transcriptase by nonnucleoside inhibitors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
20 June 2018
Reverse transcriptase of mouse mammary tumour virus: expression in bacteria, purification and biochemical characterization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
27 November 2018
Studies on the mechanism of human immunodeficiency virus reverse transcriptase. Steady-state kinetics, processivity, and polynucleotide inhibition.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220617
retrieved
27 November 2018
Identifiers
DOI
10.1042/BJ3440085
1 reference
stated in
Europe PubMed Central
PMC publication ID
1220617
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10548537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
PMC publication ID
1220617
1 reference
stated in
Europe PubMed Central
PMC publication ID
1220617
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10548537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
PubMed publication ID
10548537
1 reference
stated in
Europe PubMed Central
PMC publication ID
1220617
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10548537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit