(Q28353898)

English

Regulation of epidermal growth factor receptor endocytosis by wortmannin through activation of Rab5 rather than inhibition of phosphatidylinositol 3-kinase

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scholarly article

1 reference

Europe PubMed Central

2 July 2017

Regulation of epidermal growth factor receptor endocytosis by wortmannin through activation of Rab5 rather than inhibition of phosphatidylinositol 3-kinase (English)

1 reference

Europe PubMed Central

2 July 2017

0 references

author name string

X Chen

1

1 reference

Europe PubMed Central

2 July 2017

Z Wang

2

1 reference

Europe PubMed Central

2 July 2017

language of work or name

0 references

publication date

1 September 2001

1 reference

Europe PubMed Central

2 July 2017

1 reference

Europe PubMed Central

2 July 2017

2

1 reference

Europe PubMed Central

2 July 2017

9

1 reference

Europe PubMed Central

2 July 2017

842-849

1 reference

Europe PubMed Central

2 July 2017

Regulation of intracellular trafficking of the EGF receptor by Rab5 in the absence of phosphatidylinositol 3-kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

20 March 2017

The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

20 March 2017

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

20 March 2017

FYVE fingers bind PtdIns(3)P

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

20 March 2017

The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

20 March 2017

Cloning and characterization of a wortmannin-sensitive human phosphatidylinositol 4-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

20 March 2017

Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

20 March 2017

The Rab5 effector EEA1 is a core component of endosome docking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

7 April 2017

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

7 April 2017

Evidence for apical endocytosis in polarized hepatic cells: phosphoinositide 3-kinase inhibitors lead to the lysosomal accumulation of resident apical plasma membrane proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

29 September 2017

PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

29 September 2017

Involvement of the endosomal autoantigen EEA1 in homotypic fusion of early endosomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

29 September 2017

Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

29 September 2017

Wortmannin alters the transferrin receptor endocytic pathway in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

29 September 2017

Association of p120 ras GAP with endocytic components and colocalization with epidermal growth factor (EGF) receptor in response to EGF stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

29 September 2017

Potential sites of PI-3 kinase function in the endocytic pathway revealed by the PI-3 kinase inhibitor, wortmannin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

29 September 2017

Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

29 September 2017

Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

29 September 2017

Demethoxyviridin and wortmannin block phospholipase C and D activation in the human neutrophil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

29 September 2017

A functional PtdIns(3)P-binding motif.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

2 June 2018

Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

2 June 2018

Phosphatidylinositol 3-kinase activity is required for early endosome fusion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084034

2 June 2018

Wortmannin-sensitive Trafficking Pathways in Chinese Hamster Ovary Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11559593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catalytic domain of the p120 Ras GAP binds to RAb5 and stimulates its GTPase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11559593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/EMBO-REPORTS/KVE179

1 reference

Europe PubMed Central

2 July 2017

0 references

1 reference

Europe PubMed Central

2 July 2017

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