(Q40952577)

25 September 2017

title

PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1. (English)

1 reference

25 September 2017

Jones SM

1

1 reference

25 September 2017

Klinghoffer R

2

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25 September 2017

Prestwich GD

3

1 reference

25 September 2017

Toker A

4

1 reference

25 September 2017

Kazlauskas A

5

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25 September 2017

language of work or name

English

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publication date

1 May 1999

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25 September 2017

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25 September 2017

volume

9

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25 September 2017

issue

10

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25 September 2017

page(s)

512-521

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B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the receptor protein-tyrosine kinase

25 September 2017

cites work

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PDGF alpha- and beta-receptors activate unique and common signal transduction pathways

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7 January 2021

Structural and functional aspects of platelet-derived growth factor

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Regulation of chemotaxis by the platelet-derived growth factor receptor-beta

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7 January 2021

Involvement of phosphatidylinositide 3'-kinase and Rac in platelet-derived growth factor-induced actin reorganization and chemotaxis

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Structural determinants in the platelet-derived growth factor alpha-receptor implicated in modulation of chemotaxis.

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7 January 2021

Platelet-derived growth factor-induced phosphatidylinositol 3-kinase activation mediates actin rearrangements in fibroblasts

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7 January 2021

A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity

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7 January 2021

Phosphatidylinositol 3-kinase

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7 January 2021

Phosphoinositide kinases

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7 January 2021

Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity

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7 January 2021

The activation of phosphatidylinositol 3-kinase by Ras

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7 January 2021

Phosphatidylinositol-3-OH kinase as a direct target of Ras

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7 January 2021

The lipid products of phosphoinositide 3-kinase increase cell motility through protein kinase C.

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7 January 2021

Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

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7 January 2021

The platelet-derived growth factor beta receptor triggers multiple cytoplasmic signaling cascades that arrive at the nucleus as distinguishable inputs

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7 January 2021

A PDGF receptor domain essential for mitogenesis but not for many other responses to PDGF.

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7 January 2021

Tyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction

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7 January 2021

Control of the Balb/c-3T3 cell cycle by nutrients and serum factors: Analysis using platelet-derived growth factor and platelet-poor plasma

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7 January 2021

Dual control of cell growth by somatomedins and platelet-derived growth factor

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7 January 2021

Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression

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7 January 2021

Feedback regulation of Raf-1 and mitogen-activated protein kinase (MAP) kinase kinases 1 and 2 by MAP kinase phosphatase-1 (MKP-1).

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7 January 2021

MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo

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7 January 2021

Cell cycle-dependent activation of Ras.

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7 January 2021

Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

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7 January 2021

Cellular ras activity is required for passage through multiple points of the G0/G1 phase in BALB/c 3T3 cells

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7 January 2021

The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors

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7 January 2021

A function for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in fibroblasts during mitogenesis: requirement for insulin- and lysophosphatidic acid-mediated signal transduction

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7 January 2021

Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3'-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis

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7 January 2021

Phosphatidylinositol 3-kinase inhibitors block aortic smooth muscle cell proliferation in mid-late G1 phase: effect on cyclin-dependent kinase 2 and the inhibitory protein p27KIP1

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7 January 2021

G1 phase arrest by the phosphatidylinositol 3-kinase inhibitor LY 294002 is correlated to up-regulation of p27Kip1 and inhibition of G1 CDKs in choroidal melanoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2899%2980235-8

7 January 2021

Ras activity late in G1 phase required for p27kip1 downregulation, passage through the restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2899%2980235-8

7 January 2021

D-3 phosphoinositide metabolism in cells treated with platelet-derived growth factor

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https://api.crossref.org/works/10.1016%2FS0960-9822%2899%2980235-8

7 January 2021

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

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7 January 2021

Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK

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7 January 2021

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

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7 January 2021

Platelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phosphatidylinositol 3-kinase

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7 January 2021

Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells

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7 January 2021

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

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7 January 2021

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

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7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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7 January 2021

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

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7 January 2021

Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line

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7 January 2021

Mechanisms and consequences of activation of protein kinase B/Akt

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https://api.crossref.org/works/10.1016%2FS0960-9822%2899%2980235-8

7 January 2021

GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2899%2980235-8

7 January 2021

Repression of p27kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2899%2980235-8

7 January 2021

Ras-stimulated extracellular signal-related kinase 1 and RhoA activities coordinate platelet-derived growth factor-induced G1 progression through the independent regulation of cyclin D1 and p27

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2899%2980235-8

7 January 2021

Activation of Src family members is not required for the platelet-derived growth factor beta receptor to initiate mitogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2899%2980235-8

7 January 2021

A role for Src in signal relay by the platelet-derived growth factor alpha receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2899%2980235-8

7 January 2021

G1 events and regulation of cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2899%2980235-8

7 January 2021

Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2899%2980235-8

7 January 2021

Calcium oscillations increase the efficiency and specificity of gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2899%2980235-8

7 January 2021

Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2899%2980235-8

7 January 2021

Phosphorylation of the PDGF receptor beta subunit creates a tight binding site for phosphatidylinositol 3 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2899%2980235-8

7 January 2021

10.1016/S0960-9822(99)80235-8

Identifiers

DOI

1 reference

25 September 2017

1 reference