(Q28354735)

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Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis

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5 April 2020

2 references

27 November 2020

26 October 2022

Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis (English)

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5 April 2020

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steatohepatitis

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atherosclerosis

6 references

21 March 2019

22 March 2019

24 March 2019

17 June 2019

20 June 2019

17 September 2019

metabolic syndrome

6 references

21 March 2019

22 March 2019

24 March 2019

17 June 2019

20 June 2019

17 September 2019

metabolic dysfunction–associated steatotic liver disease

6 references

21 March 2019

22 March 2019

24 March 2019

17 June 2019

20 June 2019

17 September 2019

heterocyclic compound

1 reference

17 September 2019

1 reference

based on heuristic

inferred from title

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27 November 2020

Akifumi Kushiyama

1

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Yusuke Nakatsu

2

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Yasuka Matsunaga

3

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Takeshi Yamamotoya

4

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Keiichi Mori

5

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Koji Ueda

6

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Yuki Inoue

7

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Hideyuki Sakoda

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Midori Fujishiro

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Hiraku Ono

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Tomoichiro Asano

11

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14 December 2016

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27 November 2020

26 October 2022

Mediators of Inflammation

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21 March 2019

22 March 2019

24 March 2019

17 June 2019

20 June 2019

17 September 2019

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2016

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8603164

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Creative Commons Attribution 4.0 International

8 references

Europe PubMed Central

21 March 2019

Europe PubMed Central

22 March 2019

Europe PubMed Central

24 March 2019

Europe PubMed Central

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Europe PubMed Central

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Europe PubMed Central

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The inflammasomes

1 reference

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Two mutations convert mammalian xanthine oxidoreductase to highly superoxide-productive xanthine oxidase

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Gout-associated uric acid crystals activate the NALP3 inflammasome

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The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

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20 March 2017

Serum uric acid levels in multiple sclerosis patients correlate with activity of disease and blood-brain barrier dysfunction

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20 March 2017

Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis

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20 March 2017

Xanthine oxidoreductase is central to the evolution and function of the innate immune system

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20 March 2017

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

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7 April 2017

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

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7 April 2017

Origin and physiological roles of inflammation

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7 April 2017

Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration

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7 April 2017

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

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7 April 2017

Molecular mediators of hepatic steatosis and liver injury

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Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

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29 September 2017

Cellular cholesterol accumulation modulates high fat high sucrose (HFHS) diet-induced ER stress and hepatic inflammasome activation in the development of non-alcoholic steatohepatitis.

1 reference

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Hyperuricemia and the risk for coronary heart disease morbidity and mortality a systematic review and dose-response meta-analysis

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Uric acid lowering therapy in cardiovascular diseases.

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29 September 2017

Serum Uric Acid Levels and Risk of Metabolic Syndrome: A Dose-Response Meta-Analysis of Prospective Studies

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Febuxostat pretreatment attenuates myocardial ischemia/reperfusion injury via mitochondrial apoptosis

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A Mendelian Randomization Study of Circulating Uric Acid and Type 2 Diabetes.

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Comparative study of renal protective effects of allopurinol and N-acetyl-cysteine on contrast induced nephropathy in patients undergoing cardiac catheterization

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29 September 2017

Role of elevated serum uric acid levels at the onset of overt nephropathy in the risk for renal function decline in patients with type 2 diabetes

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29 September 2017

Hyperuricemia and risk of incident hypertension: a systematic review and meta-analysis of observational studies

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29 September 2017

Monosodium urate crystals trigger Nrf2- and heme oxygenase-1-dependent inflammation in THP-1 cells

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29 September 2017

Febuxostat ameliorates diabetic renal injury in a streptozotocin-induced diabetic rat model

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29 September 2017

NLRP3 inflammasome activation is required for fibrosis development in NAFLD.

1 reference

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29 September 2017

Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominids

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29 September 2017

Xanthine oxidase inhibition by febuxostat attenuates experimental atherosclerosis in mice

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Impact of allopurinol on risk of myocardial infarction

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Effect of plasma uric acid on antioxidant capacity, oxidative stress, and insulin sensitivity in obese subjects.

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Febuxostat, an inhibitor of xanthine oxidase, suppresses lipopolysaccharide-induced MCP-1 production via MAPK phosphatase-1-mediated inactivation of JNK

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High serum uric acid and increased risk of type 2 diabetes: a systemic review and meta-analysis of prospective cohort studies

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Caspase-1 as a central regulator of high fat diet-induced non-alcoholic steatohepatitis

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The role of inflammasome-derived IL-1 in driving IL-17 responses

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Counteracting roles of AMP deaminase and AMP kinase in the development of fatty liver

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29 September 2017

Uric acid stimulates fructokinase and accelerates fructose metabolism in the development of fatty liver

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29 September 2017

Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and -independent fatty liver.

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Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice

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29 September 2017

Relation of uric acid to serum levels of high-sensitivity C-reactive protein, triglycerides, and high-density lipoprotein cholesterol and to hepatic steatosis

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29 September 2017

Uric acid as a danger signal in gout and its comorbidities

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NASH is an Inflammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications.

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29 September 2017

Uric acid levels predict survival in men with amyotrophic lateral sclerosis

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29 September 2017

Xanthine oxidase-derived ROS upregulate Egr-1 via ERK1/2 in PA smooth muscle cells; model to test impact of extracellular ROS in chronic hypoxia

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29 September 2017

Predictors of nonalcoholic steatohepatitis in obese children

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29 September 2017

Mechanistic insights into the therapeutic use of high-dose allopurinol in angina pectoris.

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29 September 2017

Hyperuricemia is associated with histological liver damage in patients with non-alcoholic fatty liver disease.

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29 September 2017

Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells

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29 September 2017

Hyperuricemia as a mediator of the proinflammatory endocrine imbalance in the adipose tissue in a murine model of the metabolic syndrome

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29 September 2017

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29 September 2017

Serum uric Acid as a predictor for the development of nonalcoholic Fatty liver disease in apparently healthy subjects: a 5-year retrospective cohort study

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29 September 2017

Serum uric acid levels and the risk of type 2 diabetes: a prospective study.

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29 September 2017

Allopurinol and xanthine oxidase inhibition in liver ischemia reperfusion

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29 September 2017

Exaggerated liver injury induced by renal ischemia reperfusion in diabetes: effect of exenatide

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29 September 2017

Effect of high-dose allopurinol on exercise in patients with chronic stable angina: a randomised, placebo controlled crossover trial

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29 September 2017

The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome

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29 September 2017

Nitric oxide and oxidative stress in vascular disease

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29 September 2017

The NLRP3 inflammasome: a sensor for metabolic danger?

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29 September 2017

Excessive fructose intake induces the features of metabolic syndrome in healthy adult men: role of uric acid in the hypertensive response.

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29 September 2017

Uric acid-lowering treatment with benzbromarone in patients with heart failure: a double-blind placebo-controlled crossover preliminary study

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29 September 2017

Xanthine oxidoreductase depletion induces renal interstitial fibrosis through aberrant lipid and purine accumulation in renal tubules

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29 September 2017

Association between serum uric acid and development of type 2 diabetes.

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29 September 2017

Exposure of human keratinocytes to ischemia, hyperglycemia and their combination induces oxidative stress via the enzymes inducible nitric oxide synthase and xanthine oxidase

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29 September 2017

Effect of lowering uric acid on renal disease in the type 2 diabetic db/db mice

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29 September 2017

Uric acid and insulin sensitivity and risk of incident hypertension

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29 September 2017

Effect of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension: a randomized trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

Role of xanthine oxidase activation and reduced glutathione depletion in rhinovirus induction of inflammation in respiratory epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

Production, detection, and adaptive responses to free radicals in exercise

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

The potential role for xanthine oxidase inhibition in major intra-abdominal surgery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

Uric acid and the development of hypertension: the normative aging study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

Uric acid is a risk factor for myocardial infarction and stroke: the Rotterdam study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

Nonalcoholic fatty liver disease: from steatosis to cirrhosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

Hyperuricemia in childhood primary hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

Cellular distribution, metabolism and regulation of the xanthine oxidoreductase enzyme system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

Uric acid oxidation by peroxynitrite: multiple reactions, free radical formation, and amplification of lipid oxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

Hypercholesterolemia increases endothelial superoxide anion production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

Xanthine oxidase-derived hydrogen peroxide contributes to ischemia reperfusion-induced edema in gerbil brains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

Precursors of essential hypertension: pulmonary function, heart rate, uric acid, serum cholesterol, and other serum chemistries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

Metabolic effects of dietary fructose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

Predictors of an increased risk of future hypertension in Utah. A screening analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

The Pathogenesis of Hyperuricemia in Glycogen Storage Disease, Type I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

29 September 2017

Renoprotective effects of febuxostat in hyperuricemic patients with chronic kidney disease: a parallel-group, randomized, controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

2 June 2018

Febuxostat suppressed renal ischemia-reperfusion injury via reduced oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

2 June 2018

Autophagy links inflammasomes to atherosclerotic progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

2 June 2018

TRB3 is stimulated in diabetic kidneys, regulated by the ER stress marker CHOP, and is a suppressor of podocyte MCP-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

2 June 2018

Inactivation of nitric oxide by uric acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

2 June 2018

Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

2 June 2018

Hyperuricemia induces endothelial dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

2 June 2018

The pathway of adenine nucleotide catabolism and its control in isolated rat hepatocytes subjected to anoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

2 June 2018

Fructose-induced hyperuricaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

2 June 2018

Relationship between resistance to insulin-mediated glucose uptake, urinary uric acid clearance, and plasma uric acid concentration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

2 June 2018

Molybdenum requirement of female rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

2 June 2018

Oxidation--reduction potentials of turkey liver xanthine dehydrogenase and the origins of oxidase and dehydrogenase behaviour in molybdenum-containing hydroxylases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

2 June 2018

The mechanism of adenosine triphosphate depletion in the liver after a load of fructose. A kinetic study of liver adenylate deaminase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

2 June 2018

A multiple free-radical scavenging (MULTIS) study on the antioxidant capacity of a neuroprotective drug, edaravone as compared with uric acid, glutathione, and trolox

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Prooxidant and antioxidant properties of human serum ultrafiltrates toward LDL: important role of uric acid.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Observations on serum uric acid levels and the risk of idiopathic Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Uric acid levels in sera from patients with multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Intracellular ATP Decrease Mediates NLRP3 Inflammasome Activation upon Nigericin and Crystal Stimulation.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

A role for xanthine oxidase in the control of fetal cardiovascular function in late gestation sheep.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Xanthine oxidase and the fetal cardiovascular defence to hypoxia in late gestation ovine pregnancy.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Xanthine oxidoreductase is present in bile ducts of normal and cirrhotic liver.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Purification and immunohistochemical tissue localization of human xanthine oxidase.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Electron spin resonance characterization of vascular xanthine and NAD(P)H oxidase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Hypoxic preconditioning attenuates lipopolysaccharide-induced oxidative stress in rat kidneys.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Age-related increase in xanthine oxidase activity in human plasma and rat tissues.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Activities of xanthine oxidoreductase and antioxidant enzymes in different tissues of diabetic rats

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Superoxide production pathways in aortas of diabetic rats: beneficial effects of insulin therapy and endurance training.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Xanthine oxidase is one of the major sources of superoxide anion radicals in blood after reperfusion in rats with forebrain ischemia/reperfusion

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Effects of allopurinol on ischemia and reperfusion in rabbit livers

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Parameters of nitrogen metabolism during insulin hypoglycemia in rats with alloxan-induced diabetes

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Activities of DNA turnover and free radical metabolizing enzymes in cancerous human prostate tissue.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Xanthine oxidoreductase is an endogenous regulator of cyclooxygenase-2.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Uric acid stimulates vascular smooth muscle cell proliferation and oxidative stress via the vascular renin-angiotensin system

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Uric acid-induced phenotypic transition of renal tubular cells as a novel mechanism of chronic kidney disease

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Relations of serum uric acid to longitudinal blood pressure tracking and hypertension incidence

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Hyperuricemia and incidence of hypertension among men without metabolic syndrome

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Uric acid reduction rectifies prehypertension in obese adolescents.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Independent and conjoint associations of gout and hyperuricaemia with total and cardiovascular mortality

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Effects of Uric Acid on the NO Production of HUVECs and its Restoration by Urate Lowering Agents.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

The global NAFLD epidemic

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Uric acid induces fat accumulation via generation of endoplasmic reticulum stress and SREBP-1c activation in hepatocytes.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Relations of hyperuricemia with the various components of the insulin resistance syndrome in young black and white adults: the CARDIA study. Coronary Artery Risk Development in Young Adults

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Relationship between serum uric acid concentration and insulin resistance and metabolic syndrome.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Components of the metabolic syndrome and risk of cardiovascular disease and diabetes in Beaver Dam.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Serum uric acid levels and incidence of impaired fasting glucose and type 2 diabetes mellitus: a meta-analysis of cohort studies

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Allopurinol improves endothelial function and reduces oxidant-inflammatory enzyme of myeloperoxidase in metabolic syndrome

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Uric acid induces endothelial dysfunction by vascular insulin resistance associated with the impairment of nitric oxide synthesis.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

High uric acid directly inhibits insulin signalling and induces insulin resistance

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Effects of febuxostat on metabolic and renal alterations in rats with fructose-induced metabolic syndrome.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Xanthine oxidase inhibitor tungsten prevents the development of atherosclerosis in ApoE knockout mice fed a Western-type diet.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Dietary inhibition of xanthine oxidase attenuates radiation-induced endothelial dysfunction in rat aorta

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Contribution of xanthine oxidase-derived superoxide to chronic hypoxic pulmonary hypertension in neonatal rats

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Febuxostat improves the local and remote organ changes induced by intestinal ischemia/reperfusion in rats.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Enhanced Expression and Activity of Xanthine Oxidoreductase in the Failing Heart

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Systemic Oxidative Stress and Endothelial Dysfunction is Associated With an Attenuated Acute Vascular Response to Inhaled Prostanoid in Pulmonary Artery Hypertension Patients

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

No evidence for a causal link between uric acid and type 2 diabetes: a Mendelian randomisation approach

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Elovl6 promotes nonalcoholic steatohepatitis

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Use of xanthine oxidase inhibitor febuxostat inhibits renal interstitial inflammation and fibrosis in unilateral ureteral obstructive nephropathy

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F8603164

21 January 2018

Limb remote ischemic post-conditioning reduces brain reperfusion injury by reversing eNOS uncoupling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5192336

27 November 2018

Reactive oxygen species may cause myocardial reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Risk factors for tumor lysis syndrome in childhood acute myeloid leukemia treated with a uniform protocol without rasburicase prophylaxis

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Independent impact of gout on mortality and risk for coronary heart disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of oxygen-derived free radicals in gastric mucosal injury induced by ischemia or ischemia-reperfusion in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin II induces endothelial xanthine oxidase activation: role for endothelial dysfunction in patients with coronary disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Febuxostat on the Progression of Renal Disease in 5/6 Nephrectomy Rats with and without Hyperuricemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xanthine oxidase released from reperfused hind limbs mediate kupffer cell activation, neutrophil sequestration, and hepatic oxidative stress in rats subjected to tourniquet shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation between serum uric acid and risk of cardiovascular disease in essential hypertension. The PIUMA study

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum concentrations of uric acid and the metabolic syndrome among US children and adolescents

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xanthine oxidase in non-alcoholic fatty liver disease and hyperuricemia: One stone hits two birds

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preconditioning protects endothelium by preventing ET-1-induced activation of NADPH oxidase and xanthine oxidase in post-ischemic heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of serum uric acid level with non-alcoholic fatty liver disease: a cross-sectional study

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xanthine oxidoreductase is involved in macrophage foam cell formation and atherosclerosis development

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uric acid and cardiovascular risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship of serum uric acid with non-alcoholic fatty liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of xanthine oxidase and hypoxia-inducible factor 1 in Toll-like receptor 7/8-mediated activation of caspase 1 and interleukin-1β

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low uric acid levels in serum of patients with ALS: further evidence for oxidative stress?

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Risk of macrovascular disease stratified by stage of chronic kidney disease in type 2 diabetic patients: critical level of the estimated glomerular filtration rate and the significance of hyperuricemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum uric acid and cardiovascular events in successfully treated hypertensive patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uric and 1-Methyluric Acids: Metabolic Wastes or Antiradical Protectors?

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum uric acid level in patients with relapsing-remitting multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uric acid stimulates vascular smooth muscle cell proliferation by increasing platelet-derived growth factor A-chain expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigation of the oxidative effect of chronic hyperammonemia on the kidney and the possible protective effect of allopurinol

1 reference

https://pubmed.ncbi.nlm.nih.gov/28070145

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1155/2016/8603164

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28070145%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28070145%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28070145%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

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