(Q28362078)

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Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide

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scholarly article

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Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide (English)

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Raphael Mechoulam

9

object named as

R Mechoulam

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author name string

T Bisogno

1

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L Hanus

2

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L De Petrocellis

3

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S Tchilibon

4

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D E Ponde

5

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I Brandi

6

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A S Moriello

7

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J B Davis

8

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V Di Marzo

10

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language of work or name

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publication date

October 2001

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British Journal of Pharmacology

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134

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845-52

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4

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Characterization of palmitoylethanolamide transport in mouse Neuro-2a neuroblastoma and rat RBL-2H3 basophilic leukaemia cells: comparison with anandamide

1 reference

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20 March 2017

The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

20 March 2017

Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

20 March 2017

Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

20 March 2017

The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

20 March 2017

Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

20 March 2017

Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

20 March 2017

Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

20 March 2017

A novel probe for the cannabinoid receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

20 March 2017

Impaired nociception and pain sensation in mice lacking the capsaicin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

20 March 2017

The cloned capsaicin receptor integrates multiple pain-producing stimuli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

7 April 2017

Isolation and structure of a brain constituent that binds to the cannabinoid receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

7 April 2017

Vanilloid (Capsaicin) receptors and mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

7 April 2017

Formation and inactivation of endogenous cannabinoid anandamide in central neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

7 April 2017

Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

The movement of N-arachidonoylethanolamine (anandamide) across cellular membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

The fatty acid amide hydrolase (FAAH).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Cloning and functional expression of a human orthologue of rat vanilloid receptor-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Overlap between the ligand recognition properties of the anandamide transporter and the VR1 vanilloid receptor: inhibitors of anandamide uptake with negligible capsaicin-like activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

New perspectives on enigmatic vanilloid receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Immunoactive cannabinoids: therapeutic prospects for marijuana constituents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Cannabimimetic fatty acid derivatives in cancer and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Carrier-mediated uptake of the endogenous cannabinoid anandamide in RBL-2H3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Recent advantages in cannabinoid research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

The palmitoylethanolamide and oleamide enigmas : are these two fatty acid amides cannabimimetic?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Pharmacology of cannabinoid receptor ligands.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Structure-activity relationships of anandamide, an endogenous cannabinoid ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Delta9 tetrahydrocannabinol and cannabidiol alter cytokine production by human immune cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Interactions between synthetic vanilloids and the endogenous cannabinoid system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Pharmacology of cannabinoid CB1 and CB2 receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Enantiomeric cannabinoids: stereospecificity of psychotropic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Pharmacokinetics and metabolism of delta 1-tetrahydrocannabinol and other cannabinoids with emphasis on man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Stereospecificity of the discriminative stimulus functions of the dimethylheptyl homologs of 11-hydroxy-delta 8-tetrahydrocannabinol in rats and pigeons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Stereochemical effects of 11-OH-delta 8-THC-dimethylheptyl in mice and dogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Stereochemical effects of 11-OH-delta 8-tetrahydrocannabinol-dimethylheptyl to inhibit adenylate cyclase and bind to the cannabinoid receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

29 September 2017

Inhibition of anandamide amidase activity in mouse brain microsomes by cannabinoids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

2 June 2018

Hashish. I. The structure of cannabidiol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

2 June 2018

Prostaglandins and cannabis XIV. Tolerance to the stimulatory actions of cannabinoids on arachidonate metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

2 June 2018

Effect of cannabidiol on cytochrome P-450 isozymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

2 June 2018

Anxiolytic effect of cannabidiol derivatives in the elevated plus-maze.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0704327

21 January 2018

Formation of N-acyl-phosphatidylethanolamines and N-acetylethanolamines: proposed role in neurotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

27 November 2018

(-)-Delta9-tetrahydrocannabinol antagonizes the peripheral cannabinoid receptor-mediated inhibition of adenylyl cyclase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573017

27 November 2018

The absolute configuration of δ1-tetrahydrocannabinol, the major active constituent of hashish

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606325

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiepileptic Potential of Cannabidiol Analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606325

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-anticonvulsant activity relationships of cannabidiol analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606325

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Convulsions and death induced in rats by Tween 80 are prevented by capsaicin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606325

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local application of capsaicin into the draining lymph nodes attenuates expression of adjuvant-induced arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606325

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of a primary metabolite of cannabidiol

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606325

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurobehavioral activity in mice of N-vanillyl-arachidonyl-amide

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606325

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Boron triflouride etherate on alimina - a modified Lewis acid reagent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0704327

7 January 2021

based on heuristic

inferred from DOI database lookup

Anticonvulsant effects of the (-) and (+)isomers of cannabidiol and their dimethylheptyl homologs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0704327

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.BJP.0704327

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

release_n73tw72ow5c7hkbt276uo3gvny

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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