(Q28363765)

English

N-[3,4-dimethoxycinnamoyl]-anthranilic acid (tranilast) suppresses microglial inducible nitric oxide synthase (iNOS) expression and activity induced by interferon-gamma (IFN-gamma)

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Europe PubMed Central

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3 December 2019

N-[3,4-dimethoxycinnamoyl]-anthranilic acid (tranilast) suppresses microglial inducible nitric oxide synthase (iNOS) expression and activity induced by interferon-gamma (IFN-gamma) (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11704648%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

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Michael Platten

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1 reference

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3 December 2019

2

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Wick W

1 reference

Europe PubMed Central

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3 December 2019

author name string

Wischhusen J

3

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Europe PubMed Central

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3 December 2019

Weller M

4

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3 December 2019

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1 November 2001

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3 December 2019

British Journal of Pharmacology

1 reference

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3 December 2019

134

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3 December 2019

1279-1284

1 reference

Europe PubMed Central

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3 December 2019

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11704648%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

Complex formation and cooperation of protein kinase C theta and Akt1/protein kinase B alpha in the NF-kappa B transactivation cascade in Jurkat T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

20 March 2017

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

20 March 2017

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

20 March 2017

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

7 April 2017

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

7 April 2017

Nitric oxide as a secretory product of mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

7 April 2017

Nitric oxide synthases: targets for therapeutic strategies in neurological diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

29 September 2017

Tranilast inhibits protein kinase C-dependent signalling pathway linked to angiogenic activities and gene expression of retinal microcapillary endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

29 September 2017

Microglia as mediators of inflammatory and degenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

29 September 2017

JNK or IKK, AP-1 or NF-kappaB, which are the targets for MEK kinase 1 action?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

29 September 2017

Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

29 September 2017

Nitric oxide synthases: properties and catalytic mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

29 September 2017

Regulation of biosynthesis of nitric oxide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

29 September 2017

Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

29 September 2017

Pharmacological properties of N-(3',4'-dimethoxycinnamoyl) anthranilic acid (N-5'), a new anti-atopic agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

29 September 2017

N-[3,4-dimethoxycinnamoyl]-anthranilic acid (tranilast) inhibits transforming growth factor-beta relesase and reduces migration and invasiveness of human malignant glioma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

2 June 2018

Inhibitory mechanism of tranilast in human coronary artery smooth muscle cells proliferation, due to blockade of PDGF-BB-receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

2 June 2018

Delayed treatment with aminoguanidine decreases focal cerebral ischemic damage and enhances neurologic recovery in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

2 June 2018

Immunologic NO synthase: elevation in severe AIDS dementia and induction by HIV-1 gp41.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

2 June 2018

Monokine production by microglial cell clones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

2 June 2018

Inhibitory action of tranilast, an anti-allergic drug, on the release of cytokines and PGE2 from human monocytes-macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

2 June 2018

Synthesis and biological effects of NO in malignant glioma cells: modulation by cytokines including CD95L and TGF-beta, dexamethasone, and p53 gene transfer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573061

27 November 2018

Impact of tranilast on restenosis after coronary angioplasty: tranilast restenosis following angioplasty trial (TREAT)

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of interleukin 5 production with no influence on interleukin 4 production by an anti-allergic drug, tranilast, in Toxocara canis-infected mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of inducible nitric oxide synthase protects against MPTP toxicity in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell action mechanism of tranilast--effect on the expression of HLA-class II antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppressive effects of tranilast on pulmonary fibrosis and activation of alveolar macrophages in mice treated with bleomycin: role of alveolar macrophages in the fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial release of nitric oxide by the synergistic action of beta-amyloid and IFN-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effects of tranilast on proliferation, migration, and collagen synthesis of human vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation by cytokines of human astrocyte nitric oxide production

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of PDGF- and TGF-beta 1-induced collagen synthesis, migration and proliferation by tranilast in vascular smooth muscle cells from spontaneously hypertensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tranilast restores cytokine-induced nitric oxide production against platelet-derived growth factor in vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppressive effects of tranilast on the expression of inducible cyclooxygenase (COX2) in interleukin-1beta-stimulated fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0704373

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11704648%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11704648%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11704648%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

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