(Q28369942)

English

The S-acyl-2-thioethyl pronucleotide approach applied to acyclovir: part I. Synthesis and in vitro anti-hepatitis B virus activity of bis(S-acyl-2-thioethyl)phosphotriester derivatives of acyclovir

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The S-acyl-2-thioethyl pronucleotide approach applied to acyclovir: part I. Synthesis and in vitro anti-hepatitis B virus activity of bis(S-acyl-2-thioethyl)phosphotriester derivatives of acyclovir (English)

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Hepatitis B virus

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based on heuristic

inferred from title

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author name string

C Périgaud

1

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G Gosselin

2

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J L Girardet

3

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B E Korba

4

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J L Imbach

5

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language of work or name

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publication date

January 1999

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Antiviral Research

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40

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3

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167-78

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Controlled clinical trial of acyclovir in chronic hepatitis B virus infection

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In vitro inhibition of hepatitis B virus replication by 2',3'-dideoxyguanosine, 2',3'-dideoxyinosine, and 3'-azido-2',3'-dideoxythymidine in 2.2.15 (PR) cells

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Mammalian deoxyribonucleoside kinases

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Multiple drug effect analysis with confidence interval

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Failure of acyclovir to enhance the antiviral effect of alpha lymphoblastoid interferon on HBe-seroconversion in chronic hepatitis B. A multi-centre randomized controlled trial

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Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

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In search of a selective antiviral chemotherapy.

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A preliminary trial of lamivudine for chronic hepatitis B infection

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Treatment of chronic HBeAg-positive hepatitis with acyclovir. A controlled trial

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The SATE pronucleotide approach applied to acyclovir: part II. Effects of bis(SATE)phosphotriester derivatives of acyclovir on duck hepatitis B virus replication in vitro and in vivo

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Acyclovir diphosphate dimyristoylglycerol: a phospholipid prodrug with activity against acyclovir-resistant herpes simplex virus

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Acyclic guanosine analogs inhibit DNA polymerases alpha, delta, and epsilon with very different potencies and have unique mechanisms of action

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Penciclovir is a selective inhibitor of hepatitis B virus replication in cultured human hepatoblastoma cells

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Mononucleoside phosphotriester derivatives with S-acyl-2-thioethyl bioreversible phosphate-protecting groups: intracellular delivery of 3'-azido-2',3'-dideoxythymidine 5'-monophosphate

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Targeting hepatitis B therapy to the liver. Clinical pharmacokinetic considerations

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Identifiers

10.1016/S0166-3542(98)00059-X

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