(Q28375937)

English

Absence of p16, p21 and p53 gene alterations in hepatocellular carcinomas induced by N-nitrosodiethylamine or a choline-deficient L-amino acid-defined diet in rats

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scholarly article

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Absence of p16, p21 and p53 gene alterations in hepatocellular carcinomas induced by N-nitrosodiethylamine or a choline-deficient L-amino acid-defined diet in rats (English)

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author name string

Y Sasaki

1

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T Tsujiuchi

2

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N Murata

3

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T Kubozoe

4

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M Tsutsumi

5

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Y Konishi

6

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language of work or name

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publication date

28 April 2000

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152

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71-7

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1

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Disturbance of the cell cycle with colchicine enhances the growth advantage of diethylnitrosamine-initiated hepatocytes in rats.

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Inhibition by green tea extract of diethylnitrosamine-initiated but not choline-deficient, L-amino acid-defined diet-associated development of putative preneoplastic, glutathione S-transferase placental form-positive lesions in rat liver.

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Prevention by 1'-acetoxychavicol acetate of the induction but not growth of putative preneoplastic, glutathione S-transferase placental form-positive, focal lesions in the livers of rats fed a choline-deficient, L-amino acid-defined diet

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Genetic instabilities in human cancers

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Creative blocks: cell-cycle checkpoints and feedback controls

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Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

1 reference

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WAF1, a potential mediator of p53 tumor suppression

1 reference

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

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p21 is a universal inhibitor of cyclin kinases

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Accumulation of genetic alterations and their significance in each primary human cancer and cell line

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Infrequent alterations of the p16INK4A gene in liver cancer

1 reference

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Frequency of mutation and deletion of the tumor suppressor gene CDKN2A (MTS1/p16) in hepatocellular carcinoma from an Australian population

1 reference

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Inactivation of p16INK4 in hepatocellular carcinoma

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Decreased expression and rare somatic mutation of the CIP1/WAF1 gene in human hepatocellular carcinoma

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Mutational hot spot in the p53 gene in human hepatocellular carcinomas

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Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa

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Loss of heterozygosity suggests tumor suppressor gene responsible for primary hepatocellular carcinoma

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Initiation of chemical carcinogenesis requires cell proliferation

1 reference

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Frequent aberrant methylation of p16INK4a in primary rat lung tumors

1 reference

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Role of tumor suppressor genes in transplacental lung carcinogenesis.

1 reference

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Role of the p16 tumor suppressor gene in cancer

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High incidence of allelic loss on chromosome 5 and inactivation of p15INK4B and p16INK4A tumor suppressor genes in oxystress-induced renal cell carcinoma of rats

1 reference

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Induction of mutations in Ki-ras and INK4a in liver tumors of mice exposed in utero to 3-methylcholanthrene.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2899%2900430-9

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based on heuristic

inferred from DOI database lookup

Expression of p21(waf-1/cip-1) is significantly induced in the livers of LEC rats with chronic liver injury.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2899%2900430-9

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based on heuristic

inferred from DOI database lookup

Low expression of the WAF1/CIP1 gene product, p21, in enzyme-altered foci induced in rat liver by diethylnitrosamine or phenobarbital

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2899%2900430-9

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inferred from DOI database lookup

p53 mutations in hepatocellular carcinomas induced by a choline-devoid diet in male Fischer 344 rats.

1 reference

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Absence of p53 mutations and various frequencies of Ki-ras exon 1 mutations in rat hepatic tumors induced by different carcinogens.

1 reference

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Mutational analysis of three tumor suppressor genes in two models of rat hepatocarcinogenesis.

1 reference

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based on heuristic

inferred from DOI database lookup

Infrequent Ki-ras and an absence of p53 mutations in hepatocellular carcinomas induced by a choline deficient L-amino acid defined diet in rats

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Hypomethylation of CpG sites and c-myc gene overexpression in hepatocellular carcinomas, but not hyperplastic nodules, induced by a choline-deficient L-amino acid-defined diet in rats.

1 reference

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based on heuristic

inferred from DOI database lookup

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10.1016/S0304-3835(99)00430-9

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release_pmdqo2atmnbsrhw3exvnkogdze

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