(Q28376328)

English

Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, [...]

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, p21(waf1/cip1), and erythropoietin (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

apoptotic process

0 references

0 references

Gregg L. Semenza

9

object named as

G L Semenza

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

K Zaman

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

H Ryu

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

D Hall

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

K O'Donovan

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

K I Lin

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

M P Miller

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

J C Marquis

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

J M Baraban

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

R R Ratan

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

language of work or name

0 references

publication date

1 November 1999

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Journal of Neuroscience

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

19

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

9821-9830

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

22

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Definition of the roles for iron and essential fatty acids in cell cycle progression of normal human T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cystine deprivation induces oligodendroglial death: rescue by free radical scavengers and by a diffusible glial factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia. Implications for the mechanism of oxygen sensing

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: involvement of HIF-1 in tumor progression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aerobic glycolysis by proliferating cells: protection against oxidative stress at the expense of energy yield

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron induced oxidative stress and mitochondrial dysfunction: relevance to Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attempts to obtain neuroprotection in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis induced by differentiation or serum deprivation in an immortalized central nervous system neuronal cell line.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low molecular weight iron in cerebral ischemic acidosis in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of glucose transport and GLUT-1 expression by iron chelators in muscle cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular management of iron in the brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxic effects of iron for cultured mesencephalic dopaminergic neurons derived from rat embryonic brains.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective role of heme oxygenase-1 in oxidative stress-induced neuronal injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Downregulation of Cu/Zn superoxide dismutase leads to cell death via the nitric oxide-peroxynitrite pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complex genetic response of human cells to sublethal levels of pure nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of hypoxia-inducible factor 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron metabolism and Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress induces apoptosis in embryonic cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Copper, iron and zinc in Alzheimer's disease senile plaques.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of a multipotent antideath activity from bovine liver and its identification as arginase: nitric oxide-independent inhibition of neuronal apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicity of iron and hydrogen peroxide: the Fenton reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo evidence that erythropoietin protects neurons from ischemic damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of altered redox states on expression and DNA-binding activity of hypoxia-inducible factor 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle blockers mimosine, ciclopirox, and deferoxamine prevent the death of PC12 cells and postmitotic sympathetic neurons after removal of trophic support

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel site of erythropoietin production. Oxygen-dependent production in cultured rat astrocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trophic effect of erythropoietin and other hematopoietic factors on central cholinergic neurons in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxic Regulation of Lactate Dehydrogenase A

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transcription factors ATF-1 and CREB-1 bind constitutively to the hypoxia-inducible factor-1 (HIF-1) DNA recognition site

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria, free radicals, and neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron deposits in multiple sclerosis and Alzheimer's disease brains.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The potential role of iron chelators in the treatment of Parkinson's disease and related neurological disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of autoimmune neuropathological process by treatment with an iron-chelating agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional requirement of the hypoxia-responsive element in the activation of the inducible nitric oxide synthase promoter by the iron chelator desferrioxamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of protein using bicinchoninic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deferoxamine reduces early metabolic failure associated with severe cerebral ischemic acidosis in dogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative regulation of histone H1 kinase expression by mimosine, a plant amino acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The regulation of reactive oxygen species production during programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erythropoietin and erythropoietin receptor in the developing human central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of heme oxygenase protein protects neurons in cortex and striatum, but not in hippocampus, against transient forebrain ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxygen sensing and response to hypoxia by mammalian cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factor 1 and the molecular physiology of oxygen homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.19-22-09821.1999

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559391%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q28376328&oldid=1956180023"