(Q28378859)

English

(Alkylamino) piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants [...]

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16 October 2019

(Alkylamino) piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1IIIB with reduced replication phenotypes (English)

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16 October 2019

author name string

Olmsted RA

1

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16 October 2019

Slade DE

2

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16 October 2019

Kopta LA

3

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16 October 2019

Poppe SM

4

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16 October 2019

Poel TJ

5

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16 October 2019

Newport SW

6

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16 October 2019

Rank KB

7

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16 October 2019

Biles C

8

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16 October 2019

Morge RA

9

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16 October 2019

Dueweke TJ

10

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16 October 2019

Yagi Y

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16 October 2019

Romero DL

12

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16 October 2019

Thomas RC

13

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16 October 2019

Sharma SK

14

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16 October 2019

Tarpley WG

15

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16 October 2019

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1 June 1996

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16 October 2019

Journal of Virology

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16 October 2019

70

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16 October 2019

6

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16 October 2019

3698-3705

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16 October 2019

Resistance of clinical isolates of human immunodeficiency virus to antiretroviral agents

1 reference

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20 March 2017

Activity of a novel quinoxaline derivative against human immunodeficiency virus type 1 reverse transcriptase and viral replication

1 reference

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20 March 2017

pol mutations conferring zidovudine and didanosine resistance with different effects in vitro yield multiply resistant human immunodeficiency virus type 1 isolates in vivo

1 reference

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20 March 2017

U-90152, a potent inhibitor of human immunodeficiency virus type 1 replication

1 reference

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20 March 2017

A mutation in reverse transcriptase of bis(heteroaryl)piperazine-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other nonnucleoside inhibitors

1 reference

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20 March 2017

1 reference

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20 March 2017

Potent and highly selective human immunodeficiency virus type 1 (HIV-1) inhibition by a series of alpha-anilinophenylacetamide derivatives targeted at HIV-1 reverse transcriptase

1 reference

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20 March 2017

Resistance pattern of human immunodeficiency virus type 1 reverse transcriptase to quinoxaline S-2720

1 reference

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20 March 2017

Bisheteroarylpiperazine reverse transcriptase inhibitor in combination with 3'-azido-3'-deoxythymidine or 2',3'-dideoxycytidine synergistically inhibits human immunodeficiency virus type 1 replication in vitro

1 reference

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20 March 2017

Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy

1 reference

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20 March 2017

Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture

1 reference

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20 March 2017

Viral resistance to human immunodeficiency virus type 1-specific pyridinone reverse transcriptase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190245

20 March 2017

Pyridinone derivatives: specific human immunodeficiency virus type 1 reverse transcriptase inhibitors with antiviral activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190245

20 March 2017

Inhibition of HIV-1 Replication by a Nonnucleoside Reverse Transcriptase Inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190245

20 March 2017

Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

1 reference

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20 March 2017

Functional analysis of HIV-1 reverse transcriptase amino acids involved in resistance to multiple nonnucleoside inhibitors

1 reference

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20 March 2017

In vitro selection and molecular characterization of human immunodeficiency virus-1 resistant to non-nucleoside inhibitors of reverse transcriptase

1 reference

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20 March 2017

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1 reference

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7 April 2017

Viral dynamics in human immunodeficiency virus type 1 infection

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7 April 2017

HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

1 reference

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7 April 2017

In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors

1 reference

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7 April 2017

Treatment of human immunodeficiency virus type 1 (HIV-1)-infected cells with combinations of HIV-1-specific inhibitors results in a different resistance pattern than does treatment with single-drug therapy.

1 reference

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29 September 2017

Mechanism of resistance to U-90152S and sensitization to L-697,661 by a proline to leucine change at residue 236 of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase

1 reference

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29 September 2017

Mutational analysis of residue 190 of human immunodeficiency virus type 1 reverse transcriptase

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29 September 2017

Cloning and characterization of human immunodeficiency virus type 1 variants diminished in the ability to induce syncytium-independent cytolysis

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29 September 2017

A short-term clinical evaluation of L-697,661, a non-nucleoside inhibitor of HIV-1 reverse transcriptase. L-697,661 Working Group

1 reference

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2 June 2018

A single conservative amino acid substitution in the reverse transcriptase of human immunodeficiency virus-1 confers resistance to (+)-(5S)-4,5,6,7-tetrahydro-5-methyl-6-(3-methyl-2-butenyl)imidazo[4,5, 1- jk][1,4]benzodiazepin-2(1H)-thione (TIBO R8

1 reference

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2 June 2018

Envelope sequences of two new United States HIV-1 isolates

1 reference

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2 June 2018

Metal affinity chromatography of recombinant HIV-1 reverse transcriptase containing a human renin cleavable metal binding domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190245

2 June 2018

Purification and characterization of heterodimeric human immunodeficiency virus type 1 (HIV-1) reverse transcriptase produced by in vitro processing of p66 with recombinant HIV-1 protease

1 reference

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28 July 2018

Identifiers

10.1128/JVI.70.6.3698-3705.1996

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1 reference

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16 October 2019

1 reference

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16 October 2019

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