(Q28379614)

2

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P Augustijns

3

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P Annaert

4

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G Van den Mooter

5

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M N Arimilli

6

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C U Kim

7

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E De Clercq

Antimicrobial Agents and Chemotherapy

8

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language of work or name

English

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publication date

July 1998

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published in

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volume

42

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issue

7

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page(s)

1568-73

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cites work

Anti-human immunodeficiency virus activity and cellular metabolism of a potential prodrug of the acyclic nucleoside phosphonate 9-R-(2-phosphonomethoxypropyl)adenine (PMPA), Bis(isopropyloxymethylcarbonyl)PMPA

1 reference

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Antiretroviral activity and pharmacokinetics in mice of oral bis(pivaloyloxymethyl)-9-(2-phosphonylmethoxyethyl)adenine, the bis(pivaloyloxymethyl) ester prodrug of 9-(2-phosphonylmethoxyethyl)adenine

20 March 2017

1 reference

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Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine

20 March 2017

1 reference

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Carnitine deficiency induced by pivampicillin and pivmecillinam therapy

20 March 2017

1 reference

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9-[2-(Phosphonomethoxy)propyl]adenine therapy of established simian immunodeficiency virus infection in infant rhesus macaques

20 March 2017

1 reference

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Clinical pharmacokinetics of adefovir in human immunodeficiency virus type 1-infected patients

29 September 2017

1 reference

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Anti-human immunodeficiency virus (HIV) activity, safety, and pharmacokinetics of adefovir dipivoxil (9-[2-(bis-pivaloyloxymethyl)-phosphonylmethoxyethyl]adenine) in HIV-infected patients

29 September 2017

1 reference

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Prevention of SIV infection in macaques by (R)-9-(2-phosphonylmethoxypropyl)adenine

2 June 2018

1 reference

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Metabolism and pharmacokinetics of novel oral prodrugs of 9-[(R)-2-(phosphonomethoxy)propyl]adenine (PMPA) in dogs

2 June 2018

1 reference

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Oral bioavailability of the antiretroviral agent 9-(2-phosphonylmethoxyethyl)adenine (PMEA) from three formulations of the prodrug bis(pivaloyloxymethyl)-PMEA in fasted male cynomolgus monkeys

27 November 2018

1 reference

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Acyclic adenine nucleoside phosphonates in plasma determined by high-performance liquid chromatography with fluorescence detection

27 November 2018

1 reference

12 December 2020

Pharmacokinetics and metabolism of selected prodrugs of PMEA in rats

1 reference

12 December 2020

Transport, uptake, and metabolism of the bis(pivaloyloxymethyl)-ester prodrug of 9-(2-phosphonylmethoxyethyl)adenine in an in vitro cell culture system of the intestinal mucosa (Caco-2)

1 reference

12 December 2020

Effects of (R)-9-(2-phosphonylmethoxypropyl)adenine monotherapy on chronic SIV infection in macaques

1 reference

12 December 2020