(Q28382992)

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The aryl hydrocarbon receptor-activating effect of uremic toxins from tryptophan metabolism: a new concept to understand cardiovascular complications of chronic kidney disease

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The aryl hydrocarbon receptor-activating effect of uremic toxins from tryptophan metabolism: a new concept to understand cardiovascular complications of chronic kidney disease (English)

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cardiovascular disease

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13 March 2019

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chronic renal insufficiency

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13 March 2019

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DNA-binding protein

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intracellular receptor

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transcription factor

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Stéphane Poitevin

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Stephane Burtey

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Marion Sallée

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Claire Cerini

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Philippe Brunet

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Uremic solutes from colon microbes

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20 March 2017

Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor

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20 March 2017

RelB, a new partner of aryl hydrocarbon receptor-mediated transcription

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20 March 2017

Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization

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20 March 2017

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6 April 2017

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29 September 2017

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29 September 2017

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Reduction of indoxyl sulfate by AST-120 attenuates monocyte inflammation related to chronic kidney disease

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29 September 2017

Uremic serum and solutes increase post-vascular interventional thrombotic risk through altered stability of smooth muscle cell tissue factor

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29 September 2017

Src-mediated aryl hydrocarbon and epidermal growth factor receptor cross talk stimulates colon cancer cell proliferation

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29 September 2017

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29 September 2017

Polychlorinated biphenyl 77 augments angiotensin II-induced atherosclerosis and abdominal aortic aneurysms in male apolipoprotein E deficient mice.

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29 September 2017

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29 September 2017

Increased levels of total P-Cresylsulphate and indoxyl sulphate are associated with coronary artery disease in patients with diabetic nephropathy

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Oral activated charcoal adsorbent (AST-120) ameliorates extent and instability of atherosclerosis accelerated by kidney disease in apolipoprotein E-deficient mice

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29 September 2017

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Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling

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The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor

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29 September 2017

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29 September 2017

TCDD induces c-jun expression via a novel Ah (dioxin) receptor-mediated p38-MAPK-dependent pathway.

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29 September 2017

Chronic kidney disease as cause of cardiovascular morbidity and mortality

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29 September 2017

TCDD causes suppression of growth and differentiation of MCF10A, human mammary epithelial cells by interfering with their insulin receptor signaling through c-Src kinase and ERK activation.

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Predictive value of noninvasively determined endothelial dysfunction for long-term cardiovascular events in patients with peripheral vascular disease.

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29 September 2017

Review on uremic toxins: classification, concentration, and interindividual variability

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29 September 2017

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29 September 2017

Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase.

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29 September 2017

Risk stratification for postoperative cardiovascular events via noninvasive assessment of endothelial function: a prospective study

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29 September 2017

2,3,7,8-Tetrachlorodibenzo-p-dioxin affects the number and function of murine splenic dendritic cells and their expression of accessory molecules

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29 September 2017

Mechanism of increases in L-kynurenine and quinolinic acid in renal insufficiency

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29 September 2017

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29 September 2017

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2 June 2018

Nitric oxide counters the inhibitory effects of uremic toxin indoxyl sulfate on endothelial cells by governing ERK MAP kinase and myosin light chain activation

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2 June 2018

Effects of PCB126 and 17β-oestradiol on endothelium-derived vasoactive factors in human endothelial cells

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2 June 2018

Does indoxyl sulfate, a uraemic toxin, have direct effects on cardiac fibroblasts and myocytes?

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2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Oral charcoal adsorbent (AST-120) prevents progression of cardiac damage in chronic kidney disease through suppression of oxidative stress

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21 January 2018

The kynurenines are associated with oxidative stress, inflammation and the prevalence of cardiovascular disease in patients with end-stage renal disease

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21 January 2018

Altered kynurenine metabolism correlates with infarct volume in stroke.

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21 January 2018

Indoleamine 2,3-dioxygenase enzyme activity correlates with risk factors for atherosclerosis: the Cardiovascular Risk in Young Finns Study.

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21 January 2018

Indoleamine 2,3-dioxygenase activity associates with cardiovascular risk factors: the Health 2000 study

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21 January 2018

Relationship between an increased serum kynurenine/tryptophan ratio and atherosclerotic parameters in hemodialysis patients

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21 January 2018

Endothelial dysfunction and mild renal insufficiency in essential hypertension

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21 January 2018

Oral adsorbent AST-120 ameliorates endothelial dysfunction independent of renal function in rats with subtotal nephrectomy

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21 January 2018

Aryl-hydrocarbon receptor-dependent alteration of FAK/RhoA in the inhibition of HUVEC motility by 3-methylcholanthrene

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21 January 2018

The uremic solutes p-cresol and indoxyl sulfate inhibit endothelial proliferation and wound repair

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21 January 2018

Effects of indoxyl sulfate on adherens junctions of endothelial cells and the underlying signaling mechanism.

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21 January 2018

Levels of circulating endothelial progenitor cells are related to uremic toxins and vascular injury in hemodialysis patients

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21 January 2018

Antioxidant protection against PCB-mediated endothelial cell activation.

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https://api.crossref.org/works/10.3390%2FTOXINS6030934

21 January 2018

Kynurenines and oxidative status are independently associated with thrombomodulin and von Willebrand factor levels in patients with end-stage renal disease.

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6030934

21 January 2018

Activation of aryl hydrocarbon receptor mediates indoxyl sulfate-induced monocyte chemoattractant protein-1 expression in human umbilical vein endothelial cells

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6030934

21 January 2018

Indoxyl sulfate promotes proliferation of human aortic smooth muscle cells by inducing oxidative stress.

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6030934

21 January 2018

Indoxyl sulfate promotes vascular smooth muscle cell senescence with upregulation of p53, p21, and prelamin A through oxidative stress.

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6030934

21 January 2018

ROS and PDGF-beta [corrected] receptors are critically involved in indoxyl sulfate actions that promote vascular smooth muscle cell proliferation and migration

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6030934

21 January 2018

Indoxyl sulfate enhances angiotensin II signaling through upregulation of epidermal growth factor receptor expression in vascular smooth muscle cells.

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6030934

21 January 2018

Indoxyl sulfate stimulates proliferation of rat vascular smooth muscle cells.

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6030934

21 January 2018

Benzo[a]pyrene induces expression of matrix metalloproteinases and cell migration and invasion of vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6030934

21 January 2018

Modulation of the chemokines KC and MCP-1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6030934

21 January 2018

PCB 104-induced proinflammatory reactions in human vascular endothelial cells: relationship to cancer metastasis and atherogenesis

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6030934

21 January 2018

Benzo[a]pyrene induces intercellular adhesion molecule-1 through a caveolae and aryl hydrocarbon receptor mediated pathway

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6030934

21 January 2018

Indoxyl sulfate upregulates expression of ICAM-1 and MCP-1 by oxidative stress-induced NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6030934

21 January 2018

Indoxyl sulfate stimulates monocyte chemoattractant protein-1 expression in human umbilical vein endothelial cells by inducing oxidative stress through activation of the NADPH oxidase-nuclear factor-κB pathway

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6030934

21 January 2018

The role of protein-bound uremic toxins on peripheral artery disease and vascular access failure in patients on hemodialysis

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6030934

21 January 2018

Longitudinal follow-up and outcomes among a population with chronic kidney disease in a large managed care organization

1 reference

https://pubmed.ncbi.nlm.nih.gov/24599232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein-bound uremic toxins in hemodialysis patients measured by liquid chromatography/tandem mass spectrometry and their effects on endothelial ROS production

1 reference

https://pubmed.ncbi.nlm.nih.gov/24599232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stat3 contributes to indoxyl sulfate-induced inflammatory and fibrotic gene expression and cellular senescence

1 reference

https://pubmed.ncbi.nlm.nih.gov/24599232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Indoxyl sulfate promotes cardiac fibrosis with enhanced oxidative stress in hypertensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/24599232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of L-tryptophan aminotransferase in indole-3-acetic acid biosynthesis in Enterobacter cloacae

1 reference

https://pubmed.ncbi.nlm.nih.gov/24599232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The uremic solute indoxyl sulfate induces oxidative stress in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24599232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of c-Ha-ras by benzo(a)pyrene in vascular smooth muscle cells involves redox stress and aryl hydrocarbon receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/24599232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/TOXINS6030934

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24599232%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

release_bopwyhm7lvdj5d2kldnmebdgne

1 reference

https://api.fatcat.wiki/v0/release/bopwyhm7lvdj5d2kldnmebdgne

24 November 2022

based on heuristic

mapped directly with Wikidata item

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24599232%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24599232%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

ResearchGate publication ID

0 references

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