(Q28385588)

English

Novel functional view of the crocidolite asbestos-treated A549 human lung epithelial transcriptome reveals an intricate network of pathways with opposing functions

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scholarly article

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Novel functional view of the crocidolite asbestos-treated A549 human lung epithelial transcriptome reveals an intricate network of pathways with opposing functions (English)

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Joan M Hevel

1

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Laura C Olson-Buelow

2

object named as

Laura C Olson-Buelow

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Balasubramanian Ganesan

3

object named as

Balasubramanian Ganesan

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author name string

John R Stevens

4

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Jared P Hardman

5

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Ann E Aust

6

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publication date

7 August 2008

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9

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1

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376

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limma

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Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/2533023

based on heuristic

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

Stanniocalcin-1 regulates endothelial gene expression and modulates transendothelial migration of leukocytes

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Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer

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20 March 2017

TNF-alpha inhibits asbestos-induced cytotoxicity via a NF-kappaB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis

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20 March 2017

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

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20 March 2017

Oxidants and signaling by mitogen-activated protein kinases in lung epithelium

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20 March 2017

A TNF-induced gene expression program under oscillatory NF-kappaB control

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20 March 2017

Evolutionarily conserved multiple C2 domain proteins with two transmembrane regions (MCTPs) and unusual Ca2+ binding properties

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A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway

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Mammalian stanniocalcins and cancer

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20 March 2017

Stanniocalcin-1 is a naturally occurring L-channel inhibitor in cardiomyocytes: relevance to human heart failure

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20 March 2017

The molecular basis of asbestos induced lung injury

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20 March 2017

BRE: a modulator of TNF-alpha action

1 reference

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20 March 2017

Asbestos induces nuclear factor kappa B (NF-kappa B) DNA-binding activity and NF-kappa B-dependent gene expression in tracheal epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533023

20 March 2017

Hypoxia-inducible factor 2alpha regulates expression of the mitochondrial aconitase chaperone protein frataxin

1 reference

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20 March 2017

Microarray analysis and RNA silencing link fra-1 to cd44 and c-met expression in mesothelioma

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20 March 2017

The HIF family member EPAS1/HIF-2α is required for normal hematopoiesis in mice

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20 March 2017

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7 April 2017

Global histone modifications predict prognosis of resected non small-cell lung cancer.

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29 September 2017

Genome-wide mapping of RELA(p65) binding identifies E2F1 as a transcriptional activator recruited by NF-kappaB upon TLR4 activation

1 reference

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29 September 2017

BRE is an antiapoptotic protein in vivo and overexpressed in human hepatocellular carcinoma.

1 reference

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29 September 2017

FRA-1 proto-oncogene induces lung epithelial cell invasion and anchorage-independent growth in vitro, but is insufficient to promote tumor growth in vivo

1 reference

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29 September 2017

Prognostic significance of HIF-2alpha/EPAS1 expression in hepatocellular carcinoma

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29 September 2017

Induction of stanniocalcin-1 expression in apoptotic human nasopharyngeal cancer cells by p53.

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29 September 2017

Asbestos-related lung disease.

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29 September 2017

Gene expression profiles in asbestos-exposed epithelial and mesothelial lung cell lines

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29 September 2017

Asbestos-induced peribronchiolar cell proliferation and cytokine production are attenuated in lungs of protein kinase C-delta knockout mice

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29 September 2017

Apoptosis induced by crocidolite asbestos in human lung epithelial cells involves inactivation of Akt and MAPK pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533023

29 September 2017

The respiratory effects of stanniocalcin-1 (STC-1) on intact mitochondria and cells: STC-1 uncouples oxidative phosphorylation and its actions are modulated by nucleotide triphosphates

1 reference

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29 September 2017

Krüppel-like factor 4 exhibits antiapoptotic activity following gamma-radiation-induced DNA damage

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29 September 2017

Cytogenetic and molecular genetic changes in malignant mesothelioma.

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29 September 2017

Animal models of malignant mesothelioma

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29 September 2017

NR4A1, 2, 3--an orphan nuclear hormone receptor family involved in cell apoptosis and carcinogenesis

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29 September 2017

P53 mediates amosite asbestos-induced alveolar epithelial cell mitochondria-regulated apoptosis

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29 September 2017

Role of alphavbeta5 integrin receptor in endocytosis of crocidolite and its effect on intracellular glutathione levels in human lung epithelial (A549) cells

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29 September 2017

Prospects: histone deacetylase inhibitors

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29 September 2017

Transcriptional profiling of mesothelioma using microarrays

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29 September 2017

Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth

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29 September 2017

Testing association of a pathway with survival using gene expression data

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29 September 2017

BRE enhances in vivo growth of tumor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533023

29 September 2017

The transcriptosomal response of human A549 lung cells to a hydrogen peroxide-generating system: relationship to DNA damage, cell cycle arrest, and caspase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533023

29 September 2017

Mitochondrial-derived free radicals mediate asbestos-induced alveolar epithelial cell apoptosis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533023

29 September 2017

A global test for groups of genes: testing association with a clinical outcome

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29 September 2017

Use of Proteomics to Demonstrate a Hierarchical Oxidative Stress Response to Diesel Exhaust Particle Chemicals in a Macrophage Cell Line

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29 September 2017

Cell signaling and transcription factor activation by asbestos in lung injury and disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533023

29 September 2017

The mitochondria-regulated death pathway mediates asbestos-induced alveolar epithelial cell apoptosis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533023

29 September 2017

Oxidative stress and TNF-alpha induce histone acetylation and NF-kappaB/AP-1 activation in alveolar epithelial cells: potential mechanism in gene transcription in lung inflammation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533023

29 September 2017

Role of mitogen-activated protein kinases (MAPK) in cell injury and proliferation by environmental particulates

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29 September 2017

Overexpression of Betaig-h3 gene downregulates integrin alpha5beta1 and suppresses tumorigenicity in radiation-induced tumorigenic human bronchial epithelial cells

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29 September 2017

Chrysotile-induced cell transformation and transcriptional changes of c-myc oncogene in human embryo lung cells.

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29 September 2017

Differentially expressed genes in asbestos-induced tumorigenic human bronchial epithelial cells: implication for mechanism

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29 September 2017

Efflux of reduced glutathione after exposure of human lung epithelial cells to crocidolite asbestos

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29 September 2017

p53, Cip1, and Gadd153 expression following treatment of A549 cells with natural and man-made vitreous fibers

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533023

29 September 2017

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29 September 2017

Mechanisms of carcinogenesis and clinical features of asbestos-associated cancers

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29 September 2017

Participation of nitric oxide and iron in the oxidation of DNA in asbestos-treated human lung epithelial cells

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29 September 2017

Iron associated with asbestos bodies is responsible for the formation of single strand breaks in phi X174 RFI DNA

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29 September 2017

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2 June 2018

Asbestos causes DNA strand breaks in cultured pulmonary epithelial cells: role of iron-catalyzed free radicals

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2 June 2018

Asbestos: scientific developments and implications for public policy.

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2 June 2018

Iron mobilization from crocidolite asbestos greatly enhances crocidolite-dependent formation of DNA single-strand breaks in øX174 RFI DNA

1 reference

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2 June 2018

Genomic Profiling of Circulating Plasma RNA for the Analysis of Cancer

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27 November 2018

Change of heme oxygenase-1 expression in lung injury induced by chrysotile asbestos in vivo and in vitro.

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27 November 2018

The duration of nuclear extracellular signal-regulated kinase 1 and 2 signaling during cell cycle reentry distinguishes proliferation from apoptosis in response to asbestos

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27 November 2018

Crocidolite asbestos causes an induction of p53 and apoptosis in cultured A-549 lung carcinoma cells

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27 November 2018

Inducible expression of endothelial PAS domain protein-1 by hypoxia in human lung adenocarcinoma A549 cells. Role of Src family kinases-dependent pathway

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27 November 2018

Oxidant stress responses in human pleural mesothelial cells exposed to asbestos

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https://pubmed.ncbi.nlm.nih.gov/18687144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stanniocalcin 1 prevents cytosolic Ca2+ overload and cell hypercontracture in cardiomyocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18687144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of ferritin synthesis in human lung epithelial cells treated with crocidolite asbestos

1 reference

https://pubmed.ncbi.nlm.nih.gov/18687144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron Mobilization from Crocidolite Asbestos by Human Lung Carcinoma Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18687144

12 December 2020

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inferred from PubMed ID database lookup

Calcium chelator Quin-2 prevents crocidolite-induced DNA strand breakage in human white blood cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18687144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1471-2164-9-376

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