(Q28389390)

English

Lack of maternal glutamate cysteine ligase modifier subunit (Gclm) decreases oocyte glutathione concentrations and disrupts preimplantation development in mice

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scholarly article

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Lack of maternal glutamate cysteine ligase modifier subunit (Gclm) decreases oocyte glutathione concentrations and disrupts preimplantation development in mice (English)

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maternal health

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1 reference

based on heuristic

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author name string

Brooke N Nakamura

1

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Thomas J Fielder

2

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Yvonne D Hoang

3

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Jinhwan Lim

4

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Lisa A McConnachie

5

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Terrance J Kavanagh

6

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Ulrike Luderer

7

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language of work or name

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publication date

July 2011

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152

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7

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2806-15

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Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase

1 reference

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20 March 2017

Antioxidant protective mechanisms against reactive oxygen species (ROS) generated by mitochondrial P450 systems in steroidogenic cells

1 reference

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Accelerated ovarian failure induced by 4-vinyl cyclohexene diepoxide in Nrf2 null mice

1 reference

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20 March 2017

Polymorphism in glutamate-cysteine ligase modifier subunit gene is associated with impairment of nitric oxide-mediated coronary vasomotor function

1 reference

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20 March 2017

Polymorphism in the 5'-flanking region of human glutamate-cysteine ligase modifier subunit gene is associated with myocardial infarction

1 reference

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20 March 2017

Genetic mapping of GLCLC, the human gene encoding the catalytic subunit of gamma-glutamyl-cysteine synthetase, to chromosome band 6p12 and characterization of a polymorphic trinucleotide repeat within its 5' untranslated region

1 reference

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20 March 2017

Mice lacking catalase develop normally but show differential sensitivity to oxidant tissue injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

20 March 2017

Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

20 March 2017

Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

20 March 2017

Glutathione synthesis is essential for mouse development but not for cell growth in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

20 March 2017

Gonadotropin regulation of glutamate cysteine ligase catalytic and modifier subunit expression in rat ovary is subunit and follicle stage specific

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

20 March 2017

The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults

1 reference

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20 March 2017

Ovarian function in superoxide dismutase 1 and 2 knockout mice

1 reference

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20 March 2017

Reduced fertility in female mice lacking copper-zinc superoxide dismutase

1 reference

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20 March 2017

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

1 reference

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7 April 2017

Short form glutathione peroxidase 4 is the essential isoform required for survival and somatic mitochondrial functions

1 reference

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29 September 2017

A phenotypic spectrum of sexual development in Dax1 (Nr0b1)-deficient mice: consequence of the C57BL/6J strain on sex determination

1 reference

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29 September 2017

Age-associated increase in aneuploidy and changes in gene expression in mouse eggs

1 reference

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29 September 2017

Spindle formation, chromosome segregation and the spindle checkpoint in mammalian oocytes and susceptibility to meiotic error

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

29 September 2017

Glutathione levels modulate domoic acid induced apoptosis in mouse cerebellar granule cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

29 September 2017

Glutamate cysteine ligase modifier subunit deficiency and gender as determinants of acetaminophen-induced hepatotoxicity in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

29 September 2017

Female reproductive ageing: current knowledge and future trends

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

29 September 2017

Aging of oocyte, ovary, and human reproduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

29 September 2017

Genetically altered mice to evaluate glutathione homeostasis in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

29 September 2017

Evidence for functionally significant polymorphism of human glutamate cysteine ligase catalytic subunit: association with glutathione levels and drug resistance in the National Cancer Institute tumor cell line panel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

29 September 2017

The enzymes of glutathione synthesis: gamma-glutamylcysteine synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

29 September 2017

Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

29 September 2017

Mass spectrometric analysis of rat ovary and testis cytosolic glutathione S-transferases (GSTs): identification of a novel class-alpha GST, rGSTA6*, in rat testis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

29 September 2017

Reproductive assessment by continuous breeding: evolving study design and summaries of ninety studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

29 September 2017

Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

29 September 2017

Analysis of dichotomous response data from toxicological experiments involving stable laboratory mouse populations

1 reference

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29 September 2017

Potential effects of age-associated oxidative stress on mammalian oocytes/embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

2 June 2018

Insulin-like growth factor binding protein-3 gene expression is restricted to involuting corpora lutea in rat ovaries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

2 June 2018

The role of disulfide bond reduction during mammalian sperm nuclear decondensation in vivo

1 reference

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2 June 2018

Ontogeny of ovarian glutathione and sensitivity to primordial oocyte destruction by cyclophosphamide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

2 June 2018

Importance of glutathione in the acquisition and maintenance of sperm nuclear decondensing activity in maturing hamster oocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

2 June 2018

Reproductive and epigenetic outcomes associated with aging mouse oocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

27 November 2018

Sensitivity of mouse lung fibroblasts heterozygous for GPx4 to oxidative stress

1 reference

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PohnB6F1: a cross of wild and domestic mice that is a new model of extended female reproductive life span.

1 reference

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27 November 2018

Diquat induces renal proximal tubule injury in glutathione reductase-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

27 November 2018

Neurotoxicity of domoic Acid in cerebellar granule neurons in a genetic model of glutathione deficiency.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

27 November 2018

Genetic modifiers of the phenotype of mice deficient in mitochondrial superoxide dismutase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

27 November 2018

A Caenorhabditis elegans mutant lacking functional nicotinamide nucleotide transhydrogenase displays increased sensitivity to oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

27 November 2018

Role of glutathione in reproductive tract secretions on mouse preimplantation embryo development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

27 November 2018

Analyses of glutathione reductase hypomorphic mice indicate a genetic knockout

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

27 November 2018

Gonadotropin regulation of glutathione synthesis in the rat ovary

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

27 November 2018

Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

27 November 2018

Regulation of gamma-glutamate-cysteine ligase expression by oxidative stress in the mouse preimplantation embryo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

27 November 2018

Developmental patterns of zygotes from transgenic female mice with elevated tissue glutathione.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

27 November 2018

Glutathione is present in reproductive tract secretions and improves development of mouse embryos after chemically induced glutathione depletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

27 November 2018

Glutathione oxidation is associated with altered microtubule function and disrupted fertilization in mature hamster oocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

27 November 2018

Depletion of glutathione during bovine oocyte maturation reversibly blocks the decondensation of the male pronucleus and pronuclear apposition during fertilization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3115613

27 November 2018

Dynamic aspects of ovarian superoxide dismutase isozymes during the ovulatory process in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/21558310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of Ovarian Antioxidant Vitamins, Reduced Glutathione, and Lipid Peroxidation by Luteinizing Hormone and Prostaglandin F2α1

1 reference

https://pubmed.ncbi.nlm.nih.gov/21558310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of oxidative stress mimic the ability of follicle-stimulating hormone to suppress apoptosis in cultured rat ovarian follicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/21558310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of glutathione in the preimplantation mouse embryo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21558310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

gamma-glutamyltranspeptidase-deficient knockout mice as a model to study the relationship between glutathione status, mitochondrial function, and cellular function

1 reference

https://pubmed.ncbi.nlm.nih.gov/21558310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reproductive defects in gamma-glutamyl transpeptidase-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21558310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reproductive Aging in C57BL/6J Mice: Plasma Progesterone, Viable Embryos and Resorption Frequency throughout Pregnancy1

1 reference

https://pubmed.ncbi.nlm.nih.gov/21558310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21558310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical period of carbon tetrachloride-induced pregnancy loss in Fischer-344 rats, with insights into the detection of resorption sites by ammonium sulfide staining

1 reference

https://pubmed.ncbi.nlm.nih.gov/21558310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione reductase activity deficiency in homozygous Gr1a1Neu mice does not cause haemolytic anaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21558310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of Nicotinamide Nucleotide Transhydrogenase: A New Quantitive Trait Locus Accounting for Glucose Intolerance in C57BL/6J Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21558310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1210/EN.2011-0207

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