(Q28391923)

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The Cytotoxicity Mechanism of 6-Shogaol-Treated HeLa Human Cervical Cancer Cells Revealed by Label-Free Shotgun Proteomics and Bioinformatics Analysis

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scholarly article

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The Cytotoxicity Mechanism of 6-Shogaol-Treated HeLa Human Cervical Cancer Cells Revealed by Label-Free Shotgun Proteomics and Bioinformatics Analysis (English)

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Shotgun proteomics

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based on heuristic

inferred from title

author name string

Qun Liu

1

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Yong-Bo Peng

2

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Lian-Wen Qi

3

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Xiao-Lan Cheng

4

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Xiao-Jun Xu

5

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Le-Le Liu

6

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E-Hu Liu

7

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Ping Li

8

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language of work or name

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publication date

2012

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Evidence-based Complementary and Alternative Medicine

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2012

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278652

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copyright license

Creative Commons Attribution 3.0 Unported

1 January 2012

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April 2022 Public Data File from Crossref

copyright status

1 reference

April 2022 Public Data File from Crossref

Global cancer statistics

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Synergistic antileukemic interactions between 2-medroxyestradiol (2-ME) and histone deacetylase inhibitors involve Akt down-regulation and oxidative stress

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20 March 2017

14-3-3 Interacts directly with and negatively regulates pro-apoptotic Bax

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Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progression

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20 March 2017

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20 March 2017

6-Shogaol induces apoptosis in human colorectal carcinoma cellsviaROS production, caspase activation, and GADD 153 expression

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A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

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7 April 2017

Shogaols at proapoptotic concentrations induce G(2)/M arrest and aberrant mitotic cell death associated with tubulin aggregation

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29 September 2017

Low-dose valproic acid enhances radiosensitivity of prostate cancer through acetylated p53-dependent modulation of mitochondrial membrane potential and apoptosis

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29 September 2017

Characterization of the Human Cervical Mucous Proteome

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29 September 2017

6-Shogaol, an active constituent of dietary ginger, induces autophagy by inhibiting the AKT/mTOR pathway in human non-small cell lung cancer A549 cells

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29 September 2017

Control of mitochondrial apoptosis by the Bcl-2 family

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Annexins in human breast cancer: Possible predictors of pathological response to neoadjuvant chemotherapy

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29 September 2017

The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development

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The role of herbs and spices in cancer prevention

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Emerging applications of network and pathway analysis in drug discovery and development

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Proteomics characterization of the cytotoxicity mechanism of ganoderic acid D and computer-automated estimation of the possible drug target network

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29 September 2017

Treatment of squamous cell carcinoma of the uterine cervix with radiation therapy alone: long-term survival, late complications, and incidence of second cancers

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29 September 2017

The apoptosome: signalling platform of cell death

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29 September 2017

Proteome informatics for cancer research: from molecules to clinic

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Steamed American ginseng berry: ginsenoside analyses and anticancer activities

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29 September 2017

Applications for protein sequence-function evolution data: mRNA/protein expression analysis and coding SNP scoring tools

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29 September 2017

A proteomic investigation into a human gastric cancer cell line BGC823 treated with diallyl trisulfide

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29 September 2017

Binding of 14-3-3 proteins and nuclear export control the intracellular localization of the mitotic inducer Cdc25.

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Establishment of an ectopically expressed and functional PRMT1 for proteomic analysis of arginine-methylated proteins

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2 June 2018

Clinical proteomics and biomarker discovery.

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21 January 2018

Simultaneous determination of 6-gingerol, 8-gingerol, 10-gingerol and 6-shogaol in rat plasma by liquid chromatography-mass spectrometry: Application to pharmacokinetics

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21 January 2018

Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms

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21 January 2018

Anti-invasion effects of 6-shogaol and 6-gingerol, two active components in ginger, on human hepatocarcinoma cells

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21 January 2018

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10.1155/2012/278652

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