(Q28393835)

2

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Alexander Sedykh

3

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Wenyi Wang

4

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Menghang Xia

5

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Hao Zhu

Environmental Health Perspectives

6

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language of work or name

English

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publication date

May 2016

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published in

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volume

124

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issue

5

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page(s)

634-41

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cites work

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Adverse outcome pathways: a conceptual framework to support ecotoxicology research and risk assessment

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Clinical implications of dihydropyrimidine dehydrogenase (DPD) activity in 5-FU-based chemotherapy: mutations in the DPD gene, and DPD inhibitory fluoropyrimidines

20 March 2017

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Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes

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Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes

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An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

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Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and RXR alpha

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Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

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Involvement of the host DNA-repair enzyme TDP2 in formation of the covalently closed circular DNA persistence reservoir of hepatitis B viruses

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Construction and analysis of a human hepatotoxicity database suitable for QSAR modeling using post-market safety data

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Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing.

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Progress in computational toxicology

29 September 2017

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Critical evaluation of human oral bioavailability for pharmaceutical drugs by using various cheminformatics approaches

29 September 2017

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PubChem BioAssay: 2014 update

29 September 2017

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Improving the human hazard characterization of chemicals: a Tox21 update

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29 September 2017

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Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation

29 September 2017

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Predicting drug-induced hepatotoxicity using QSAR and toxicogenomics approaches

29 September 2017

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NRF2 Oxidative Stress Induced by Heavy Metals is Cell Type Dependent.

29 September 2017

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Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.

29 September 2017

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29 September 2017

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Use of in vitro HTS-derived concentration-response data as biological descriptors improves the accuracy of QSAR models of in vivo toxicity

29 September 2017

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29 September 2017

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Impact of visceral adipose tissue on liver metabolism. Part I: heterogeneity of adipose tissue and functional properties of visceral adipose tissue

29 September 2017

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Toxicology. Transforming environmental health protection

29 September 2017

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Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases

29 September 2017

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Predictive QSAR modeling workflow, model applicability domains, and virtual screening

29 September 2017

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29 September 2017

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Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries

29 September 2017

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High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening

29 September 2017

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Rational selection of training and test sets for the development of validated QSAR models

29 September 2017

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Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival

29 September 2017

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The relationship between the thyroid gland and the liver

29 September 2017

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Oxidative stress: oxidants and antioxidants

29 September 2017

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Mechanisms of free radical oxidation of unsaturated lipids

29 September 2017

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Clinical associations between thyroid and liver diseases

29 September 2017

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Epidemiological and experimental studies on the effects of methyl isocyanate on the course of pregnancy

29 September 2017

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Experimental and Theoretical Understanding of the Gas Phase Oxidation of Atmospheric Amides with OH Radicals: Kinetics, Products, and Mechanisms

29 September 2017

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Tdp1 protects against oxidative DNA damage in non-dividing fission yeast

27 November 2018

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A gene expression biomarker provides early prediction and mechanistic assessment of hepatic tumor induction by nongenotoxic chemicals

27 November 2018

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Novel variable selection quantitative structure--property relationship approach based on the k-nearest-neighbor principle

27 November 2018

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Mechanism of hepatic drug oxidation and its relationship to individual differences in rates of oxidation in man

27 November 2018

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Defining Molecular Initiating Events in the Adverse Outcome Pathway Framework for Risk Assessment

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12 December 2020

Predicting idiosyncratic drug-induced liver injury: some recent advances

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12 December 2020

Toxicity testing in the 21st century: a view from the pharmaceutical industry

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Fatality after oxyphenbutazone in Still's disease

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