(Q28397728)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22273745%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Aryl hydrocarbon receptor (AhR) regulates silica-induced inflammation but not fibrosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22273745%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22273745%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

author name string

Benjamin P Seaver

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22273745%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

David M Shepherd

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22273745%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

language of work or name

English

0 references

publication date

23 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22273745%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

published in

Toxicological Sciences

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22273745%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

volume

126

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22273745%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22273745%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

page(s)

554-568

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22273745%20AND%20SRC:MED&resulttype=core&format=json

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

21 January 2020

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Critical role of MARCO in crystalline silica-induced pulmonary inflammation

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The role of pro- and anti-inflammatory responses in silica-induced lung fibrosis

19 March 2017

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The sources of inflammatory mediators in the lung after silica exposure

19 March 2017

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19 March 2017

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Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases

19 March 2017

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19 March 2017

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Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms

7 April 2017

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Progression of lung inflammation and damage in rats after cessation of silica inhalation

19 March 2017

1 reference

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Occupational exposure to crystalline silica and risk of systemic lupus erythematosus: a population-based, case-control study in the southeastern United States

19 March 2017

1 reference

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Time course of pulmonary response of rats to inhalation of crystalline silica: NF-kappa B activation, inflammation, cytokine production, and damage

19 March 2017

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Time course of pulmonary response of rats to inhalation of crystalline silica: histological results and biochemical indices of damage, lipidosis, and fibrosis

19 March 2017

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Interleukin-10 and the interleukin-10 receptor

19 March 2017

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Occupational exposure to crystalline silica and autoimmune disease

19 March 2017

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The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells

19 March 2017

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Alpha-quartz-induced chemokine expression by rat lung epithelial cells: effects of in vivo and in vitro particle exposure

19 March 2017

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Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

19 March 2017

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The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

7 April 2017

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The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

7 April 2017

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AhR deficiency impairs expression of LPS-induced inflammatory genes in mice

7 April 2017

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A clinical perspective of IL-1β as the gatekeeper of inflammation

29 September 2017

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Endogenous and exogenous ligands of aryl hydrocarbon receptor: current state of art.

29 September 2017

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External influences on the immune system via activation of the aryl hydrocarbon receptor.

29 September 2017

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An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

29 September 2017

1 reference

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The aryl hydrocarbon receptor: fine-tuning the immune-response

29 September 2017

1 reference

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γδ T cells protect against lung fibrosis via IL-22.

29 September 2017

1 reference

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Inflammasome inhibition as a pathogenic stealth mechanism

29 September 2017

1 reference

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Innate immune processes are sufficient for driving silicosis in mice.

29 September 2017

1 reference

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Aryl hydrocarbon receptor activation reduces dendritic cell function during influenza virus infection

29 September 2017

1 reference

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Functional and phenotypic effects of AhR activation in inflammatory dendritic cells

29 September 2017

1 reference

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Effects of TCDD on the fate of naive dendritic cells.

29 September 2017

1 reference

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Dioxin and immune regulation: emerging role of aryl hydrocarbon receptor in the generation of regulatory T cells

29 September 2017

1 reference

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Molecular mechanisms of the physiological functions of the aryl hydrocarbon (dioxin) receptor, a multifunctional regulator that senses and responds to environmental stimuli

29 September 2017

1 reference

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Hypersensitivity of aryl hydrocarbon receptor-deficient mice to lipopolysaccharide-induced septic shock

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307612

Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307612

The aryl hydrocarbon receptor in immunity

29 September 2017

1 reference

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Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

29 September 2017

1 reference

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AHR-mediated immunomodulation: the role of altered gene transcription

29 September 2017

1 reference

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Elevated asymmetric dimethylarginine alters lung function and induces collagen deposition in mice

29 September 2017

1 reference

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Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells.

29 September 2017

1 reference

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Invasive and noninvasive methods for studying pulmonary function in mice.

29 September 2017

1 reference

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NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta

29 September 2017

1 reference

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New developments in the understanding of immunology in silicosis

29 September 2017

1 reference

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Nucleotide-binding oligomerization domain-like receptors: intracellular pattern recognition molecules for pathogen detection and host defense

29 September 2017

1 reference

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Basic pathogenetic mechanisms in silicosis: current understanding

29 September 2017

1 reference

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Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra

29 September 2017

1 reference

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Effect of inhaled crystalline silica in a rat model: time course of pulmonary reactions

29 September 2017

1 reference

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Crucial role of interleukin-1beta and nitric oxide synthase in silica-induced inflammation and apoptosis in mice

29 September 2017

1 reference

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Diseases caused by silica: mechanisms of injury and disease development

29 September 2017

1 reference

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2,3,7,8-Tetrachlorodibenzo-p-dioxin affects the number and function of murine splenic dendritic cells and their expression of accessory molecules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307612

Ah receptor signaling pathways

29 September 2017

1 reference

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Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation

29 September 2017

1 reference

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The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity

2 June 2018

1 reference

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Antigen-presenting cell population dynamics during murine silicosis.

2 June 2018

1 reference

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Protection from fluorescein isothiocyanate-induced fibrosis in IL-13-deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblasts

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307612

Flow cytometric identification of murine neutrophils and monocytes.

2 June 2018

1 reference

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Pulmonary response to silica or titanium dioxide: inflammatory cells, alveolar macrophage-derived cytokines, and histopathology

2 June 2018

1 reference

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Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

2 June 2018

1 reference

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IL-6 receptor-mediated lung Th2 cytokine networking in silica-induced pulmonary fibrosis.

27 November 2018

1 reference

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IL-17A-producing gammadelta T and Th17 lymphocytes mediate lung inflammation but not fibrosis in experimental silicosis

27 November 2018

1 reference

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3,3'-Diindolylmethane attenuates experimental arthritis and osteoclastogenesis

27 November 2018

1 reference

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Langerhans cell maturation and contact hypersensitivity are impaired in aryl hydrocarbon receptor-null mice

27 November 2018

1 reference

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Noninvasive and invasive pulmonary function in mouse models of obstructive and restrictive respiratory diseases

27 November 2018

1 reference

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Developmental exposure to the potent aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin Impairs the cell-mediated immune response to infection with influenza a virus, but enhances elements of innate immunity

27 November 2018

1 reference

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Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell-mediated effects on regulatory T cells

27 November 2018

1 reference

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Aryl hydrocarbon receptor activation impairs the priming but not the recall of influenza virus-specific CD8+ T cells in the lung

27 November 2018

1 reference

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Activation of the aryl hydrocarbon receptor increases pulmonary neutrophilia and diminishes host resistance to influenza A virus.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307612

Accurate and simple discrimination of mouse pulmonary dendritic cell and macrophage populations by flow cytometry: methodology and new insights.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307612

IL-13 activates a mechanism of tissue fibrosis that is completely TGF-beta independent

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307612

Treatment with alpha-galactosylceramide attenuates the development of bleomycin-induced pulmonary fibrosis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307612

Interleukin-1-receptor antagonist in the Muckle-Wells syndrome.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307612

Bleomycin-induced lung fibrosis in IL-4-overexpressing and knockout mice.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307612

Sequence variation and phylogenetic history of the mouse Ahr gene

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307612

Adverse effects of crystalline silica exposure. American Thoracic Society Committee of the Scientific Assembly on Environmental and Occupational Health

27 November 2018

1 reference

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Increase in a distinct pulmonary macrophage subset possessing an antigen-presenting cell phenotype and in vitro APC activity following silica exposure

27 November 2018

1 reference

12 December 2020

Genetic linkage analysis of pulmonary fibrotic response to silica in mice

1 reference

12 December 2020

Scavenger receptor class A type I/II (CD204) null mice fail to develop fibrosis following silica exposure

1 reference

12 December 2020

Studies on 2,3,7,8-tetrachlorodibenzo-p-dioxin induced immune suppression and decreased resistance to infection: endotoxin hypersensitivity, serum zinc concentrations and effect of thymosin treatment

1 reference

12 December 2020

Polymorphisms of the IL-1 gene complex in coal miners with silicosis

1 reference

12 December 2020

The role of cell injury and the continuing inflammatory response in the generation of silicotic pulmonary fibrosis

1 reference

12 December 2020

Silica induces apoptosis in macrophages and the release of interleukin-1 alpha and interleukin-1 beta

1 reference

12 December 2020

TH1/TH2 immune response in lung fibroblasts in interstitial lung disease

1 reference

12 December 2020

Increased elastase and myeloperoxidase activity associated with neutrophil recruitment by IL-17 in airways in vivo

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12 December 2020

Identifiers

DOI

10.1093/TOXSCI/KFS024

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22273745%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22273745%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22273745%20AND%20SRC:MED&resulttype=core&format=json