(Q28472958)

2

0 references

Banu Sis

3

0 references

David Bond

4

0 references

Karl P Fischer

5

0 references

D Lorne J Tyrrell

6

0 references

Jamie T Lewis

7

0 references

Norman M Kneteman

Creative Commons Attribution 4.0 International

8

0 references

language of work or name

English

0 references

publication date

18 February 2010

0 references

published in

PLOS One

0 references

volume

5

0 references

issue

2

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page(s)

e9209

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copyright license

start time

18 February 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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The extent of heterocellular communication mediated by gap junctions is predictive of bystander tumor cytotoxicity in vitro

19 March 2017

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19 March 2017

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Hepatitis C virus replication in mice with chimeric human livers

7 April 2017

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Mechanisms of liver regeneration and their clinical implications

7 April 2017

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Development of an HSV-tk transgenic mouse model for study of liver damage

29 September 2017

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Near completely humanized liver in mice shows human-type metabolic responses to drugs

29 September 2017

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Human hepatocytes as a tool for studying toxicity and drug metabolism.

29 September 2017

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Suicide gene therapy mediated by the Herpes Simplex virus thymidine kinase gene/Ganciclovir system: fifteen years of application.

29 September 2017

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Cytochrome P450 pharmacogenetics in drug development: in vitro studies and clinical consequences

29 September 2017

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Liver regeneration: from laboratory to clinic

29 September 2017

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29 September 2017

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Mitochondria and cell death. Mechanistic aspects and methodological issues

29 September 2017

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Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice

29 September 2017

1 reference

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Gap junctions promote the bystander effect of herpes simplex virus thymidine kinase in vivo.

29 September 2017

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Gap junctions play a role in the 'bystander effect' of the herpes simplex virus thymidine kinase/ganciclovir system in vitro

29 September 2017

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Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

29 September 2017

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Herpes simplex virus thymidine kinase/ganciclovir-mediated apoptotic death of bystander cells.

29 September 2017

1 reference

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In situ use of suicide genes for cancer therapy.

29 September 2017

1 reference

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Regression of established macroscopic liver metastases after in situ transduction of a suicide gene

29 September 2017

1 reference

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In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy

29 September 2017

1 reference

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Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors

29 September 2017

1 reference

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Comparison of levels of aldehyde oxidase with cytochrome P450 activities in human liver in vitro

29 September 2017

1 reference

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Clinical Implications of Enzyme Induction and Enzyme Inhibition

29 September 2017

1 reference

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Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs

29 September 2017

1 reference

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A Mup promoter-thymidine kinase reporter gene shows relaxed tissue-specific expression and confers male sterility upon transgenic mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

Enzyme induction and inhibition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

The herpes simplex virus type 1 thymidine kinase is expressed in the testes of transgenic mice under the control of a cryptic promoter

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

DNA rearrangement causes hepatocarcinogenesis in albumin-plasminogen activator transgenic mice

29 September 2017

1 reference

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Processing tissue and cells for transmission electron microscopy in diagnostic pathology and research

29 September 2017

1 reference

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Ganciclovir nucleotides accumulate in mitochondria of rat liver cells expressing the herpes simplex virus thymidine kinase gene

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

Application of human liver microsomes in metabolism-based drug-drug interactions: in vitro-in vivo correlations and the Abbott Laboratories experience

2 June 2018

1 reference

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Chicken NKx2-8, a novel homeobox gene expressed during early heart and foregut development.

2 June 2018

1 reference

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Human malignant brain tumor response to herpes simplex thymidine kinase (HSVtk)/ganciclovir gene therapy

2 June 2018

1 reference

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Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir

2 June 2018

1 reference

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In situ retroviral-mediated gene transfer for the treatment of brain tumors in rats

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

Measurement of liver microsomal cytochrome p450 (CYP2D6) activity using [O-methyl-14C]dextromethorphan

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

Gene therapy of hepatoma: bystander effects and non-apoptotic cell death induced by thymidine kinase and ganciclovir

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

Infertility in male transgenic mice: disruption of sperm development by HSV-tk expression in postmeiotic germ cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

Role of platelets on liver regeneration after 90% hepatectomy in mice.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

Anti-HCV therapies in chimeric scid-Alb/uPA mice parallel outcomes in human clinical application

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

A simple and rapid method to determine the zygosity of uPA-transgenic SCID mice.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

Gap junction-mediated bystander effect in primary cultures of human malignant gliomas with recombinant expression of the HSVtk gene

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

Prediction of human hepatic clearance from in vivo animal experiments and in vitro metabolic studies with liver microsomes from animals and humans.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

Cytogenetic genotoxicity of anti-herpes purine nucleoside analogues in CHO cells expressing the thymidine kinase gene of herpes simplex virus type 1: comparison of ganciclovir, penciclovir and aciclovir

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

A phase I/II study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for recurrent glioblastoma. Study Group on Gene Therapy for Glioblastoma

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

Severe hepatic dysfunction after adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene and ganciclovir administration.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

Flagellar and acrosomal abnormalities associated with testicular HSV-tk expression in the mouse.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823785

Hepatocyte transplantation in a model of toxin-induced liver disease: variable therapeutic effect during replacement of damaged parenchyma by donor cells

27 November 2018

1 reference

12 December 2020

Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy

1 reference

12 December 2020

Replacement of diseased mouse liver by hepatic cell transplantation

1 reference

12 December 2020

Drug-induced hepatotoxicity

1 reference

12 December 2020

Different transmission rates of herpesvirus thymidine kinase reporter transgenes from founder male parents and male parents of subsequent generations

1 reference

12 December 2020

Down-regulation of c-myc mRNA after completion of liver regeneration in transgenic mice expressing hepatocyte growth factor in liver

1 reference

12 December 2020

Ganciclovir-induced ablation non-proliferating thyrocytes expressing herpesvirus thymidine kinase occurs by p53-independent apoptosis

1 reference

12 December 2020

Gene therapy for malignant pleural mesothelioma

1 reference

12 December 2020