(Q28473277)

2

0 references

Guri Giaever

6

0 references

Corey Nislow

7

0 references

Jan Wildenhain

object named as

Jan Wildenhain

4

0 references

Lawrence E Heisler

object named as

Lawrence E Heisler

3

0 references

Elke Ericson

1

object named as

Elke Ericson

0 references

author name string

Mike Tyers

Creative Commons Attribution 4.0 International

5

0 references

language of work or name

English

0 references

publication date

8 August 2008

0 references

published in

PLOS Genetics

0 references

volume

4

0 references

issue

8

0 references

page(s)

e1000151

0 references

copyright license

start time

8 August 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration

1 reference

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Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast.

19 March 2017

1 reference

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Genome-wide requirements for resistance to functionally distinct DNA-damaging agents

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Functional profiling of the Saccharomyces cerevisiae genome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Atypical antipsychotics in the treatment of schizophrenia: systematic overview and meta-regression analysis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

A knowledge-based approach in designing combinatorial or medicinal chemistry libraries for drug discovery. 1. A qualitative and quantitative characterization of known drug databases

19 March 2017

1 reference

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Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Two isoforms of a human actin-related protein show nuclear localization and mutually selective expression between brain and other tissues

19 March 2017

1 reference

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Cluster analysis and display of genome-wide expression patterns

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis

19 March 2017

1 reference

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Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Slow axonal transport of the cytosolic chaperonin CCT with Hsc73 and actin in motor neurons

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

TM4: a free, open-source system for microarray data management and analysis

19 March 2017

1 reference

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Using GOstats to test gene lists for GO term association

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

The chemical genomic portrait of yeast: uncovering a phenotype for all genes

7 April 2017

1 reference

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Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions

7 April 2017

1 reference

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Cheminformatics analysis and learning in a data pipelining environment

29 September 2017

1 reference

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Critical role of the proline-rich region in Huntingtin for aggregation and cytotoxicity in yeast.

29 September 2017

1 reference

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Yeast as a tool to uncover the cellular targets of drugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Flanking sequences profoundly alter polyglutamine toxicity in yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

A network of protein interactions determines polyglutamine toxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Global analysis of gene function in yeast by quantitative phenotypic profiling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Mutation in the epsilon subunit of the cytosolic chaperonin-containing t-complex peptide-1 (Cct5) gene causes autosomal recessive mutilating sensory neuropathy with spastic paraplegia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Myocarditis, pericarditis and cardiomyopathy in patients treated with clozapine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Yeast genome-wide drug-induced haploinsufficiency screen to determine drug mode of action

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Chemogenomic profiling: identifying the functional interactions of small molecules in yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

From genetics and genomics to drug discovery: yeast rises to the challenge

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Structure and function of a protein folding machine: the eukaryotic cytosolic chaperonin CCT.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Huntington toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

An overview of side effects caused by typical antipsychotics.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Pharmacogenetics of antipsychotic treatment: lessons learned from clozapine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Quantitative phenotypic analysis of yeast deletion mutants using a highly parallel molecular bar-coding strategy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Clozapine-induced agranulocytosis. Incidence and risk factors in the United States

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Genomic profiling of drug sensitivities via induced haploinsufficiency.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Physiological mechanism by which acetyl CoA carboxylase is regulated

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483942

Myocarditis during clozapine treatment

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000151

Acute myocarditis associated with clozapine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000151

Modulation of prion-dependent polyglutamine aggregation and toxicity by chaperone proteins in the yeast model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000151

Yeast cells provide insight into alpha-synuclein biology and pathobiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000151

Cytotoxicity of a mutant huntingtin fragment in yeast involves early alterations in mitochondrial OXPHOS complexes II and III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000151

Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000151

Genome-wide analysis of barcoded Saccharomyces cerevisiae gene-deletion mutants in pooled cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000151

A unique and universal molecular barcode array

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000151

Exploring the Mode-of-Action of Bioactive Compounds by Chemical-Genetic Profiling in Yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000151

10.1371/JOURNAL.PGEN.1000151

21 January 2018

Identifiers

DOI

1 reference

5009017

5009017

1 reference

1 reference

1 reference