(Q28476222)

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Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from Northwestern Uganda following melarsoprol withdrawal

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Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from Northwestern Uganda following melarsoprol withdrawal (English)

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infectious disease

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Trypanosoma brucei

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Trypanosoma brucei gambiense infectious disease

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Michael P. Barrett

5

object named as

Michael P Barrett

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object named as

Enock Matovu

6

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object named as

Pascal Mäser

4

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Harry P de Koning

object named as

Harry P de Koning

3

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author name string

Anne J N Kazibwe

1

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Barbara Nerima

2

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Michael P Barrett

5

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language of work or name

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publication date

29 September 2009

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PLoS Neglected Tropical Diseases

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3

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9

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e523

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copyright license

Creative Commons Attribution 4.0 International

29 September 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

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Nifurtimox plus Eflornithine for late-stage sleeping sickness in Uganda: a case series

1 reference

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19 March 2017

Genotypic and phenotypic characterization of Trypanosoma brucei gambiense isolates from Ibba, South Sudan, an area of high melarsoprol treatment failure rate

1 reference

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Melarsoprol- and pentamidine-resistant Trypanosoma brucei rhodesiense populations and their cross-resistance

1 reference

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Use of multiple displacement amplification to increase the detection and genotyping of trypanosoma species samples immobilized on FTA filters.

1 reference

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Drugs and drug resistance in African trypanosomiasis

1 reference

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Targeting of toxic compounds to the trypanosome's interior

1 reference

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Roles for the Trypanosoma brucei P2 transporter in DB75 uptake and resistance

1 reference

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Real-time PCR for detection of Trypanosoma brucei in human blood samples

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The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: additional insights on diamidine resistance in african trypanosomes.

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Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei

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1 reference

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1 reference

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1 reference

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1 reference

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Re-emergence of epidemic sleeping sickness in southern Sudan

1 reference

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29 September 2017

Therapeutic failure of melarsoprol among patients treated for late stage T.b. gambiense human African trypanosomiasis in Uganda

1 reference

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A nucleoside transporter from Trypanosoma brucei involved in drug resistance.

1 reference

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Arsenical-resistant trypanosomes lack an unusual adenosine transporter

1 reference

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Human African trypanosomiasis: use of double centrifugation of cerebrospinal fluid to detect trypanosomes

1 reference

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Uptake of pentamidine in Trypanosoma brucei brucei is mediated by the P2 adenosine transporter and at least one novel, unrelated transporter

1 reference

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2 June 2018

The haematocrit centrifuge technique for the diagnosis of African trypanosomiasis

1 reference

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Detection of Trypanosoma congolense and Trypanosoma brucei subspecies by DNA amplification using the polymerase chain reaction

1 reference

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The rise and fall of sleeping sickness

1 reference

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21 January 2018

Further evidence for a link between melarsoprol resistance and P2 transporter function in African trypanosomes.

1 reference

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A diamidine-resistant Trypanosoma equiperdum clone contains a P2 purine transporter with reduced substrate affinity.

1 reference

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21 January 2018

Loss of the high-affinity pentamidine transporter is responsible for high levels of cross-resistance between arsenical and diamidine drugs in African trypanosomes

1 reference

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21 January 2018

Trypanosoma brucei brucei: expression of drug resistance in vitro.

1 reference

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Detection of arsenical drug resistance in Trypanosoma brucei with a simple fluorescence test

1 reference

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The fall and rise of sleeping sickness

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Human African trypanosomiasis (sleeping sickness): epidemiological update

1 reference

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27 November 2018

Molecular pharmacology of adenosine transport in Trypanosoma brucei: P1/P2 revisited

1 reference

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27 November 2018

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10.1371/JOURNAL.PNTD.0000523

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