(Q28476544)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858147%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Transcriptional profiling of human liver identifies sex-biased genes associated with polygenic dyslipidemia and coronary artery disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858147%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

1 reference

coronary artery disease

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858147%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

David J. Waxman

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858147%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

6

Ulrich M Zanger

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858147%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

author name string

Yijing Zhang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858147%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Kathrin Klein

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858147%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Aarathi Sugathan

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858147%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Najlla Nassery

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858147%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

language of work or name

English

0 references

publication date

12 August 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858147%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858147%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858147%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858147%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

page(s)

e23506

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858147%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

11 February 2020

copyright license

start time

12 August 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

19 March 2017

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Mapping the genetic architecture of gene expression in human liver

19 March 2017

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Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

19 March 2017

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Newly identified loci that influence lipid concentrations and risk of coronary artery disease

19 March 2017

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A histone H3 lysine 27 demethylase regulates animal posterior development

19 March 2017

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UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

19 March 2017

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PAML 4: phylogenetic analysis by maximum likelihood

19 March 2017

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Genomic imprinting in mammals: emerging themes and established theories

19 March 2017

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

19 March 2017

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X-inactivation profile reveals extensive variability in X-linked gene expression in females

19 March 2017

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The DNA sequence and biology of human chromosome 19

19 March 2017

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Control of pancreas and liver gene expression by HNF transcription factors

19 March 2017

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Gender-specific gene expression in post-mortem human brain: localization to sex chromosomes

19 March 2017

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DAVID: Database for Annotation, Visualization, and Integrated Discovery

19 March 2017

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19 March 2017

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Biochemical analysis of the Kruppel-associated box (KRAB) transcriptional repression domain

19 March 2017

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19 March 2017

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Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

6 April 2017

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Cluster analysis and display of genome-wide expression patterns

19 March 2017

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The human homolog of a mouse-imprinted gene, Peg3, maps to a zinc finger gene-rich region of human chromosome 19q13.4

19 March 2017

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19 March 2017

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MLL targets SET domain methyltransferase activity to Hox gene promoters

21 January 2018

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19 March 2017

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Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

7 April 2017

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A receptor-mediated pathway for cholesterol homeostasis

7 April 2017

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The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus

7 April 2017

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Pathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver.

7 April 2017

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Sexual dimorphism in body fat distribution and risk for cardiovascular diseases

29 September 2017

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Global survey of escape from X inactivation by RNA-sequencing in mouse

29 September 2017

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Sex differences in epigenetic regulation of the estrogen receptor-alpha promoter within the developing preoptic area

29 September 2017

1 reference

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Intrinsic sex differences in the early growth hormone responsiveness of sex-specific genes in mouse liver

29 September 2017

1 reference

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The imprinted gene PEG3 inhibits Wnt signaling and regulates glioma growth

29 September 2017

1 reference

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The effect of PPAR-alpha agonism on apolipoprotein metabolism in humans

29 September 2017

1 reference

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Epigenetic regulation of estrogen receptor alpha gene expression in the mouse cortex during early postnatal development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Coronary artery disease: Are men and women created equal?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Systems biology asks new questions about sex differences

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Hormones in synergy: regulation of the pituitary gonadotropin genes.

29 September 2017

1 reference

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Cardiovascular risk factors in hypopituitary GH-deficient adults

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

YY1's role in DNA methylation of Peg3 and Xist

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Hormonal regulation of CYP1A expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

A review of bile acid sequestrants: potential mechanism(s) for glucose-lowering effects in type 2 diabetes mellitus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Sex differences in the expression of hepatic drug metabolizing enzymes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Plasma lipoproteins: genetic influences and clinical implications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Sex differences in histone modifications in the neonatal mouse brain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Sex-specific genetic architecture of human disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Elucidating the role of gonadal hormones in sexually dimorphic gene coexpression networks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

X chromosome dosage compensation: how mammals keep the balance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

An evolutionarily conserved sexual signature in the primate brain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Sex-specific differences in CYP450 isoforms in humans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Sex-specific early growth hormone response genes in rat liver

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Sex-specific differences in expression of histone demethylases Utx and Uty in mouse brain and neurons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Liver-specific hepatocyte nuclear factor-4alpha deficiency: greater impact on gene expression in male than in female mouse liver.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Large-scale population study of human cell lines indicates that dosage compensation is virtually complete

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Aberrant splicing caused by single nucleotide polymorphism c.516G>T [Q172H], a marker of CYP2B6*6, is responsible for decreased expression and activity of CYP2B6 in liver

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Genomic imprinting effects on brain development and function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Gender differences in drug responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Perspectives on dyslipidemia and coronary heart disease in women: an update.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Tissue-specific expression and regulation of sexually dimorphic genes in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Sex chromosome specialization and degeneration in mammals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Genome-wide estimation of gender differences in the gene expression of human livers: statistical design and analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Inherited disorders of HDL metabolism and atherosclerosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Inherited apolipoprotein A-V deficiency in severe hypertriglyceridemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Lipid metabolism in women

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Sex is a major determinant of CYP3A4 expression in human liver

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Gender difference in growth hormone response in adults

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Maximum-Likelihood Models for Combined Analyses of Multiple Sequence Data

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

SRY and sex determination in mammals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Gender difference in the response of growth hormone (GH)-deficient adults to GH therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Comparison of atherosclerotic lesions and HDL-lipid levels in male, female, and testosterone-treated female mice from strains C57BL/6, BALB/c, and C3H.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male genes and repression of female genes revealed by microarray analysis.

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023506

Rosetta error model for gene expression analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023506

Major molecular differences between mammalian sexes are involved in drug metabolism and renal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023506

Association of human serum apolipoprotein A5 with lipid profiles affected by gender.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023506

Oral, more than transdermal, estrogen therapy improves lipids and lipoprotein(a) in postmenopausal women: a randomized, placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023506

Effects of transdermal estrogen replacement therapy on plasma levels of nitric oxide and plasma lipids in postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023506

Effects of ovariectomy on PPAR alpha, SREBP-1c, and SCD-1 gene expression in the rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023506

The relationship between sex hormones and lipid profile in men with coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023506

Elevated basal FSH in normal cycling women is associated with unfavourable lipid levels and increased cardiovascular risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023506

Growth hormone secretion pattern is an independent regulator of growth hormone actions in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023506

Generation of mice transgenic for human CYP2C18 and CYP2C19: characterization of the sexually dimorphic gene and enzyme expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023506

Growth hormone determines sexual dimorphism of hepatic cytochrome P450 3A4 expression in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023506

Sex is a major determinant of CYP3A4 expression in human liver

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155567

Molecular evolution of sex-biased genes in Drosophila

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21858147

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0023506

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858147%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

0 references

release_ektoofi5hnfffnm5eytv5bo3a4

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ektoofi5hnfffnm5eytv5bo3a4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21858147%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

21858147

2 references