(Q28476716)

English

Lysine auxotrophy combined with deletion of the SecA2 gene results in a safe and highly immunogenic candidate live attenuated vaccine for tuberculosis

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scholarly article

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Lysine auxotrophy combined with deletion of the SecA2 gene results in a safe and highly immunogenic candidate live attenuated vaccine for tuberculosis (English)

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attenuated vaccine

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based on heuristic

inferred from title

Steven A Porcelli

9

object named as

Steven A Porcelli

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author name string

Joseph Hinchey

1

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Bo Y Jeon

2

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Holly Alley

3

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Bing Chen

4

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Michael Goldberg

5

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Steven Derrick

6

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Sheldon Morris

7

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William R Jacobs

8

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Sunhee Lee

10

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language of work or name

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publication date

10 January 2011

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6

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1

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e15857

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copyright license

Creative Commons CC0 License

10 January 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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Specialized transduction: an efficient method for generating marked and unmarked targeted gene disruptions in Mycobacterium tuberculosis, M. bovis BCG and M. smegmatis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

7 April 2017

Immunology of tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

7 April 2017

New use of BCG for recombinant vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

7 April 2017

Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

7 April 2017

New vaccines for tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

Towards improved understanding of protective mechanisms induced by the BCG vaccine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

Tuberculosis vaccine research: the impact of immunology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

Next generation: tuberculosis vaccines that elicit protective CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

Advances in tuberculosis vaccine strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

No life without death--apoptosis as prerequisite for T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guérin mutants that secrete listeriolysin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

The success and failure of BCG - implications for a novel tuberculosis vaccine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

Antigen-independent memory CD8 T cells do not develop during chronic viral infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

Memory CD8 T-cell differentiation during viral infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

Survival perspectives from the world's most successful pathogen, Mycobacterium tuberculosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

Similarities and differences in CD4+ and CD8+ effector and memory T cell generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

Vaccine efficacy of a lysine auxotroph of Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

Two nonredundant SecA homologues function in mycobacteria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

CD8(+) T cells participate in the memory immune response to Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

Functional impairment of simian immunodeficiency virus-specific CD8+ T cells during the chronic phase of infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

Biosynthesis of diaminopimelate, the precursor of lysine and a component of peptidoglycan, is an essential function of Mycobacterium smegmatis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

29 September 2017

Extragenic suppression of the requirement for diaminopimelate in diaminopimelate auxotrophs of Mycobacterium smegmatis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018466

2 June 2018

Tuberculosis vaccines - an update.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015857

21 January 2018

Live attenuated mutants of Mycobacterium tuberculosis as candidate vaccines against tuberculosis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015857

21 January 2018

Ablation of CD8 and CD4 T cell responses by high viral loads

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015857

21 January 2018

Danish bacille Calmette-Guérin vaccine-induced disease in human immunodeficiency virus-infected children.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015857

21 January 2018

A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015857

21 January 2018

Immune response toMycobacterium bovis bacille Calmette Guérin infection in major histocompatibility complex class I- and II-deficient knock-out mice: contribution of CD4 and CD8 T cells to acquired resistance

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015857

21 January 2018

Global Epidemiology of Tuberculosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21264335

12 December 2020

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Identifiers

10.1371/JOURNAL.PONE.0015857

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2011PLoSO...615857H

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