(Q28476751)

1

0 references

Yuan M Zhou

2

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Ivy Hsieh

3

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Doron C Greenbaum

4

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Juan C Engel

Creative Commons Attribution 4.0 International

6

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language of work or name

English

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publication date

September 2011

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published in

PLOS Pathogens

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volume

7

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issue

9

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page(s)

e1002139

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copyright license

start time

1 September 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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NF-kappaB and the immune response

19 March 2017

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Good cop, bad cop: the different faces of NF-kappaB

19 March 2017

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Oscillations in NF-kappaB signaling control the dynamics of gene expression

19 March 2017

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Activation of Transcription Factors AP-1 and NF-κB in Murine Chagasic Myocarditis

19 March 2017

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Alternative activation of macrophages

19 March 2017

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Surface-targeted lysosomal membrane glycoprotein-1 (Lamp-1) enhances lysosome exocytosis and cell invasion by Trypanosoma cruzi

19 March 2017

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Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection

19 March 2017

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Amastigotes of Trypanosoma cruzi sustain an infective cycle in mammalian cells

19 March 2017

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Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B

19 March 2017

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Advances in Chagas disease drug development: 2009-2010

19 March 2017

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The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.

29 September 2017

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Delineation of diverse macrophage activation programs in response to intracellular parasites and cytokines

29 September 2017

1 reference

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Trypanosoma cruzi induces the reactive oxygen species-PARP-1-RelA pathway for up-regulation of cytokine expression in cardiomyocytes

29 September 2017

1 reference

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Specific chemotherapy of Chagas disease: relevance, current limitations and new approaches

29 September 2017

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Two approaches to discovering and developing new drugs for Chagas disease.

29 September 2017

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Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20.

29 September 2017

1 reference

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Dimerization of the I kappa B kinase-binding domain of NEMO is required for tumor necrosis factor alpha-induced NF-kappa B activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Lipopolysaccharide induces CXCL2/macrophage inflammatory protein-2 gene expression in enterocytes via NF-kappaB activation: independence from endogenous TNF-alpha and platelet-activating factor

29 September 2017

1 reference

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Trypanosoma cruzi infection and nuclear factor kappa B activation prevent apoptosis in cardiac cells

29 September 2017

1 reference

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Probing Trypanosoma cruzi biology with DNA microarrays

29 September 2017

1 reference

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Host cell signaling and Trypanosoma cruzi invasion: do all roads lead to lysosomes?

29 September 2017

1 reference

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Role of the Toll/interleukin-1 receptor signaling pathway in host resistance and pathogenesis during infection with protozoan parasites.

29 September 2017

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Alternatively activated macrophages during parasite infections

29 September 2017

1 reference

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Inhibition of NF-kappaB activity by IkappaBbeta in association with kappaB-Ras

29 September 2017

1 reference

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Distinctions between c-Rel and other NF-kappaB proteins in immunity and disease

29 September 2017

1 reference

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Differential phosphorylation of the signal-responsive domain of I kappa B alpha and I kappa B beta by I kappa B kinases

29 September 2017

1 reference

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Hijacking of host cell IKK signalosomes by the transforming parasite Theileria

29 September 2017

1 reference

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Immediate/early response to Trypanosoma cruzi infection involves minimal modulation of host cell transcription

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Altered expression of cruzipain and a cathepsin B-like target in a Trypanosoma cruzi cell line displaying resistance to synthetic inhibitors of cysteine-proteinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Cell-specific activation of nuclear factor-kappaB by the parasite Trypanosoma cruzi promotes resistance to intracellular infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Infection of endothelial cells with Trypanosoma cruzi activates NF-kappaB and induces vascular adhesion molecule expression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Regulation of inducible gene expression by the transcription factor NF-kappaB.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Overexpression of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, is associated with enhanced metacyclogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Stage-regulated expression of cruzipain, the major cysteine protease of Trypanosoma cruzi is independent of the level of RNA1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Transformation as an approach to functional analysis of the major cysteine protease of Trypanosoma cruzi

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Host cell invasion by Trypanosoma cruzi is potentiated by activation of bradykinin B(2) receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Upregulation of the secretory pathway in cysteine protease inhibitor-resistant Trypanosoma cruzi

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Parasite persistence correlates with disease severity and localization in chronic Chagas' disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

The sequence, organization, and expression of the major cysteine protease (cruzain) from Trypanosoma cruzi

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Arginase induction promotes Trypanosoma cruzi intracellular replication in Cruzipain-treated J774 cells through the activation of multiple signaling pathways

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002139

Cysteine protease isoforms from Trypanosoma cruzi, cruzipain 2 and cruzain, present different substrate preference and susceptibility to inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002139

Heparan sulfate modulates kinin release by Trypanosoma cruzi through the activity of cruzipain

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002139

Different signaling pathways are involved in cardiomyocyte survival induced by a Trypanosoma cruzi glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002139

Enzymatic activity, protein expression, and gene sequence of cruzipain in virulent and attenuated Trypanosoma cruzi strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002139

Humoral immune response to cruzipain and cardiac dysfunction in chronic Chagas disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002139

Preformed membrane-associated stores of interleukin (IL)-12 are a previously unrecognized source of bioactive IL-12 that is mobilized within minutes of contact with an intracellular parasite

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002139

Inhibition of lipopolysaccharide-induced macrophage IL-12 production by Leishmania mexicana amastigotes: the role of cysteine peptidases and the NF-kappaB signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002139

Toll-like receptor 2 regulates interleukin-1beta-dependent cardiomyocyte hypertrophy triggered by Trypanosoma cruzi

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002139

NF-kappa B: ten years after

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002139

An effect of parasite-encoded arginase on the outcome of murine cutaneous leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002139

Impaired production of proinflammatory cytokines and host resistance to acute infection with Trypanosoma cruzi in mice lacking functional myeloid differentiation factor 88.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002139

Parasite persistence in the aetiology of Chagas disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002139

Increased susceptibility of Stat4-deficient and enhanced resistance in Stat6-deficient mice to infection with Trypanosoma cruzi

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002139

Inhibition of a p38/stress-activated protein kinase-2-dependent phosphatase restores function of IL-1 receptor-associate kinase-1 and reverses Toll-like receptor 2- and 4-dependent tolerance of macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002139

Proteolytic Cleavage of the p65-RelA Subunit of NF-κB during Poliovirus Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002139

Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Nitric oxide and anti-protozoan chemotherapy

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Cruzipain, a major Trypanosoma cruzi antigen, conditions the host immune response in favor of parasite

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Trypanosoma cruzi: skin-penetration kinetics of vector-derived metacyclic trypomastigotes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Antigen-specific Th1 but not Th2 cells provide protection from lethal Trypanosoma cruzi infection in mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Cysteine protease inhibitors alter Golgi complex ultrastructure and function in Trypanosoma cruzi.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Trypanosoma cruzi: biological characterization of clones derived from chronic chagasic patients. II. Quantitative analysis of the intracellular cycle

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

In vivo administration of recombinant IFN-gamma induces macrophage activation, and prevents acute disease, immune suppression, and death in experimental Trypanosoma cruzi infections

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164631

Aerobic glucose fermentation by Trypanosoma cruzi axenic culture amastigote-like forms during growth and differentiation to epimastigotes

27 November 2018

1 reference

12 December 2020

Determination of arginase activity in macrophages: a micromethod

1 reference

12 December 2020

The mechanisms of Trypanosoma cruzi invasion of mammalian cells

1 reference

12 December 2020

High resolution localization of cruzipain and Ssp4 in Trypanosoma cruzi by replica staining label fracture

1 reference

12 December 2020

High expression of a functional cruzipain by a non-infective and non-pathogenic Trypanosoma cruzi clone

1 reference

12 December 2020

Trypanosoma cruzi-mediated IFN-gamma-inducible nitric oxide output in macrophages is regulated by iNOS mRNA stability

1 reference

12 December 2020

Trypanosoma cruzi: quantification and analysis of the infectivity of cloned stocks

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.1002139

Identifiers

DOI

1 reference

release_6bjntek2d5c4jdrncpbqlobfzq

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/6bjntek2d5c4jdrncpbqlobfzq

24 November 2022

mapped directly with Wikidata item

1 reference

1 reference

PubMed publication ID

21909255

1 reference