(Q28477606)

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1α,25(OH)2-3-epi-vitamin D3, a natural physiological metabolite of vitamin D3: its synthesis, biological activity and crystal structure with its receptor

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21483824%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1α,25(OH)2-3-epi-vitamin D3, a natural physiological metabolite of vitamin D3: its synthesis, biological activity and crystal structure with its receptor (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21483824%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

crystal structure

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cholecalciferol

1 reference

based on heuristic

inferred from title

Ferdinand Molnár

1

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28 January 2020

11

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28 January 2020

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Rita Sigüeiro

2

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28 January 2020

Yoshiteru Sato

3

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28 January 2020

Clarisse Araujo

4

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28 January 2020

Inge Schuster

5

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28 January 2020

Pierre Antony

6

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28 January 2020

Jean Peluso

7

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28 January 2020

Christian Muller

8

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28 January 2020

Antonio Mouriño

9

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28 January 2020

Dino Moras

10

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28 January 2020

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publication date

31 March 2011

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28 January 2020

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28 January 2020

6

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28 January 2020

e18124

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28 January 2020

3

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28 January 2020

copyright license

Creative Commons Attribution 4.0 International

31 March 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Superagonistic fluorinated vitamin D3 analogs stabilize helix 12 of the vitamin D receptor

1 reference

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19 March 2017

Structure-based design of a superagonist ligand for the vitamin D nuclear receptor

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19 March 2017

Noncalcemic Actions of Vitamin D Receptor Ligands

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19 March 2017

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19 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

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19 March 2017

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1 reference

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19 March 2017

Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands

1 reference

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19 March 2017

The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand

1 reference

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19 March 2017

FACS-optimized mutants of the green fluorescent protein (GFP)

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7 April 2017

Evolution of our understanding of vitamin D.

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29 September 2017

Control of autoimmune diseases by the vitamin D endocrine system

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29 September 2017

The vitamin D receptor as a therapeutic target

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29 September 2017

Vitamin D receptor agonists specifically modulate the volume of the ligand-binding pocket

1 reference

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29 September 2017

Spatio-temporal activation of chromatin on the human CYP24 gene promoter in the presence of 1alpha,25-Dihydroxyvitamin D3.

1 reference

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29 September 2017

C-3 epimerization of vitamin D3 metabolites and further metabolism of C-3 epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and subsequently metabolized through C-1alpha or C-24 hydroxylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069065

29 September 2017

Vitamin D receptor as a drug discovery target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069065

29 September 2017

1Alpha,25-dihydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxy vitamin D3: production and biological activity studies in pulmonary alveolar type II cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069065

29 September 2017

Functional and structural characterization of the insertion region in the ligand binding domain of the vitamin D nuclear receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069065

29 September 2017

Differential activities of 1alpha,25-dihydroxy-16-ene-vitamin D(3) analogs and their 3-epimers on human promyelocytic leukemia (HL-60) cell differentiation and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069065

29 September 2017

Natural metabolites of 1alpha,25-dihydroxyvitamin D(3) retain biologic activity mediated through the vitamin D receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069065

29 September 2017

Selective interaction of vitamin D receptor with transcriptional coactivators by a vitamin D analog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069065

29 September 2017

Differentiation-related pathways of 1 alpha,25-dihydroxycholecalciferol metabolism in human colon adenocarcinoma-derived Caco-2 cells: production of 1 alpha,25-dihydroxy-3epi-cholecalciferol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069065

29 September 2017

1 alpha,25-(OH)2-vitamin D3 analogs with minimal in vivo calcemic activity can stimulate significant transepithelial calcium transport and mRNA expression in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069065

29 September 2017

Luminescent oxygen channeling immunoassay: measurement of particle binding kinetics by chemiluminescence.

1 reference

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29 September 2017

Isolation and identification of 24,25-dihydroxycholecalciferol, a metabolite of vitamin D made in the kidney

1 reference

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29 September 2017

25,26-dihydroxycholecalciferol, a metabolite of vitamin D3 with intestinal calcium transport activity

1 reference

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29 September 2017

Side-chain hydroxylation of vitamin D3 and its physiological implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069065

29 September 2017

Nonhypercalcemic 1,25-(OH)2D3 analogs potently induce the human osteocalcin gene promoter stably transfected into rat osteosarcoma cells (ROSCO-2)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069065

29 September 2017

The in vitro production and activity of 24, 25-dihydroxycholecalciferol in cartilage and calvarium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069065

29 September 2017

25-Hydroxyvitamin D3 26,23-lactone: a new in vivo metabolite of vitamin D

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069065

29 September 2017

An expeditious route to 1alpha,25-dihydroxyvitamin D(3) and its analogues by an aqueous tandem palladium-catalyzed a-ring closure and suzuki coupling to the C/D unit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069065

2 June 2018

Metabolic pathways from 1 alpha,25-dihydroxyvitamin D3 to 1 alpha,25-dihydroxyvitamin D3-26,23-lactone. Stereo-retained and stereo-selective lactonization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069065

2 June 2018

Lanthanides in organic chemistry. 1. Selective 1,2 reductions of conjugated ketones

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018124

21 January 2018

Efficient synthesis of the A-ring phosphine oxide building block useful for 1 alpha,25-dihydroxy vitamin D(3) and analogues

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018124

21 January 2018

A synthetic method for formyl→ethynyl conversion (RCHO→RCCH or RCCR′)

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018124

21 January 2018

Ligand recognition by the vitamin D receptor

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018124

21 January 2018

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

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21 January 2018

Structure and function of 3 alpha-hydroxysteroid dehydrogenase

1 reference

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27 November 2018

Demonstration that 1 beta,25-dihydroxyvitamin D3 is an antagonist of the nongenomic but not genomic biological responses and biological profile of the three A-ring diastereomers of 1 alpha,25-dihydroxyvitamin D3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069065

27 November 2018

25-OHD3-26,23-lactone: A metabolite of Vitamin D3 that is 5 times more potent than 25-OHD3 in the rat plasma competitive protein binding radioassay

1 reference

https://pubmed.ncbi.nlm.nih.gov/21483824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two nuclear signalling pathways for vitamin D

1 reference

https://pubmed.ncbi.nlm.nih.gov/21483824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rat intestinal 25-hydroxyvitamin D3- and 1alpha,25-dihydroxyvitamin D3-24-hydroxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21483824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1alpha,25-dihydroxy-16-ene-23-yne-vitamin D3 and 1alpha,25-dihydroxy-16-ene-23-yne-20-epi-vitamin D3: analogs of 1alpha,25-dihydroxyvitamin D3 that resist metabolism through the C-24 oxidation pathway are metabolized through the C-3 epimerization pa

1 reference

https://pubmed.ncbi.nlm.nih.gov/21483824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neonatal human foreskin keratinocytes produce 1,25-dihydroxyvitamin D3

1 reference

https://pubmed.ncbi.nlm.nih.gov/21483824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pd-catalyzed carbocyclization-Negishi cross-coupling cascade: a novel approach to 1alpha,25-dihydroxyvitamin D3 and analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/21483824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 Alpha-25,26-trihydroxyvitamin D3: an in vivo and in vitro metabolite of vitamin D3

1 reference

https://pubmed.ncbi.nlm.nih.gov/21483824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin D and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21483824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1alpha,25-dihydroxy-3-epi-vitamin D3: in vivo metabolite of 1alpha,25-dihydroxyvitamin D3 in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21483824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Residues of the human nuclear vitamin D receptor that form hydrogen bonding interactions with the three hydroxyl groups of 1alpha,25-dihydroxyvitamin D3

1 reference

https://pubmed.ncbi.nlm.nih.gov/21483824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human bone cells in culture metabolize 25-hydroxyvitamin D3 to 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3

1 reference

https://pubmed.ncbi.nlm.nih.gov/21483824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1Alpha,25-dihydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/21483824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Probing a Water Channel near the A-Ring of Receptor-Bound 1α,25-Dihydroxyvitamin D3 with Selected 2α-Substituted Analogues†

1 reference

https://pubmed.ncbi.nlm.nih.gov/21483824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of 1alpha,25-dihydroxy-3-epi-vitamin D3 in two rat osteosarcoma cell lines (UMR 106 and ROS 17/2.8): existence of the C-3 epimerization pathway in ROS 17/2.8 cells in which the C-24 oxidation pathway is not expressed

1 reference

https://pubmed.ncbi.nlm.nih.gov/21483824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0018124

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21483824%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

2011PLoSO...618124M

0 references

release_y4kscojno5bmfckgrzuq3t4b7u

1 reference

https://api.fatcat.wiki/v0/release/y4kscojno5bmfckgrzuq3t4b7u

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21483824%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21483824%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

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