(Q28477668)

21494667

title

Antidepressants and breast and ovarian cancer risk: a review of the literature and researchers' financial associations with industry (English)

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21 September 2020

14 July 2021

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21 September 2020

14 July 2021

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21 September 2020

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21494667

industrial sector

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14 July 2021

6

Krista F Huybrechts

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author name string

Lisa Cosgrove

1

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Ling Shi

2

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David E Creasey

3

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Maria Anaya-McKivergan

4

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Jessica A Myers

Creative Commons Attribution 4.0 International

5

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language of work or name

English

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publication date

6 April 2011

7 references

13 March 2019

14 March 2019

24 March 2019

3 April 2019

17 June 2019

21 September 2020

14 July 2021

8 references

13 March 2019

14 March 2019

24 March 2019

3 April 2019

17 June 2019

29 May 2020

21 September 2020

14 July 2021

6

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issue

4

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page(s)

e18210

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copyright license

7 references

13 March 2019

14 March 2019

24 March 2019

3 April 2019

17 June 2019

21 September 2020

on focus list of Wikimedia project

14 July 2021

copyright status

copyrighted

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ScienceSource

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cites work

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Focus on the funding and production of evidence rather than its publication

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Medical journals are an extension of the marketing arm of pharmaceutical companies

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The antidepressants imipramine, clomipramine, and citalopram induce apoptosis in human acute myeloid leukemia HL-60 cells via caspase-3 activation

19 March 2017

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Meta-analysis in clinical trials

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Scope and impact of financial conflicts of interest in biomedical research: a systematic review

29 September 2017

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The antidepressant sertraline inhibits translation initiation by curtailing mammalian target of rapamycin signaling.

7 April 2017

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Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: a population based cohort study

29 September 2017

1 reference

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The antidepressants maprotiline and fluoxetine have potent selective antiproliferative effects against Burkitt lymphoma independently of the norepinephrine and serotonin transporters.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Fluoxetine induces apoptosis in ovarian carcinoma cell line OVCAR-3 through reactive oxygen species-dependent activation of nuclear factor-kappaB.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

National patterns in antidepressant medication treatment

29 September 2017

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The challenge of conflict of interest in medicine

29 September 2017

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Antidepressant medication use and breast cancer risk

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Fluoxetine inhibits the extracellular signal regulated kinase pathway and suppresses growth of cancer cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Effect of antidepressants on body weight, ethology and tumor growth of human pancreatic carcinoma xenografts in nude mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Evaluation of the potential anti-cancer activity of the antidepressant sertraline in human colon cancer cell lines and in colorectal cancer-xenografted mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Inhibitory effect of fluoxetine on lymphoma growth through the modulation of antitumor T-cell response by serotonin-dependent and independent mechanisms.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Desipramine induces apoptotic cell death through nonmitochondrial and mitochondrial pathways in different types of human colon carcinoma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Financial ties and concordance between results and conclusions in meta-analyses: retrospective cohort study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Medication use and the risk of breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

29 September 2017

Managing the menopause.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Cytotoxicity of different selective serotonin reuptake inhibitors (SSRIs) against cancer cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Paroxetine-induced apoptosis in human osteosarcoma cells: activation of p38 MAP kinase and caspase-3 pathways without involvement of [Ca2+]i elevation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

The 5-HT2A serotoninergic receptor is expressed in the MCF-7 human breast cancer cell line and reveals a mitogenic effect of serotonin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Use of antidepressant medications in relation to the incidence of breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Why olanzapine beats risperidone, risperidone beats quetiapine, and quetiapine beats olanzapine: an exploratory analysis of head-to-head comparison studies of second-generation antipsychotics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Hormetic effects of hormones, antihormones, and antidepressants on cancer cell growth in culture: in vivo correlates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Cancer biology and hormesis: human tumor cell lines commonly display hormetic (biphasic) dose responses

29 September 2017

1 reference

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29 September 2017

The corporate coauthor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Effects of amitriptyline and fluoxetine upon the in vitro proliferation of tumor cell lines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Depression and cancer: mechanisms and disease progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Systematic review of the epidemiologic and trial evidence of an association between antidepressant medication and breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Selective serotonin reuptake inhibitors directly signal for apoptosis in biopsy-like Burkitt lymphoma cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Risk of epithelial ovarian cancer in relation to use of antidepressants, benzodiazepines, and other centrally acting medications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

The effects of tricyclic antidepressants on breast cancer risk

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

U-shaped dose-responses in biology, toxicology, and public health

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Evaluation of conflict of interest in economic analyses of new drugs used in oncology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Self-reported use of antidepressants or benzodiazepine tranquilizers and risk of epithelial ovarian cancer: evidence from two combined case-control studies (Massachusetts, United States).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Do antidepressants cause, promote, or inhibit cancers?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Influence of inhibitors of serotonin uptake on intestinal epithelium and colorectal carcinomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

EMBASE and MEDLINE searches.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

A case-control study of breast cancer and psychotropic drug use.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Cytostatic activity of commonly used tricyclic antidepressants

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

General and genetic toxicology of paroxetine

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Circumvention of pleiotropic drug resistance in subcutaneous tumours in vivo with verapamil and clomipramine

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Stimulation of malignant growth in rodents by antidepressant drugs at clinically relevant doses

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Chronic variable stress facilitates tumoral growth: reversal by imipramine administration

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Carcinogenicity studies of fluoxetine hydrochloride in rats and mice

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Enhancement by the tricyclic antidepressant, desipramine, of experimental carcinogenesis in rat colon induced by azoxymethane.

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018210

DMBA-induced mammary tumor growth in rats exhibiting increased or decreased ability to cope with stress due to early postnatal handling or antidepressant treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018210

Antidepressant medication use and breast cancer risk: a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018210

Antidepressant use and breast cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018210

Use of selective serotonin reuptake inhibitors and the risk of breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018210

Breast cancer risk in a large cohort of female antidepressant medication users

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018210

Psychotropic medication use and risk of hormone-related cancers: the New York University Women's Health Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018210

Risk of breast cancer in association with exposure to two different groups of tricyclic antidepressants

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018210

Incidence of cancer and antidepressant medication: record linkage study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018210

Genotoxic activity of five antidepressant hydrazines in a battery of in vivo and in vitro short-term tests.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018210

Chlorpromazine and related antipsychotic tricyclic compounds competitively inhibit the interaction between tumor-promoting phorbol esters and their specific receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018210

Assessment of DNA damage in C6 glioma cells after antidepressant treatment using an alkaline comet assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018210

Conflicts of interest and disclosure in the American Psychiatric Association's Clinical Practice Guidelines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018210

Is Academic Medicine for Sale?

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018210

Antidepressant Medications and Risk for Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018210

Curbing industry sponsor's incentive to design post-approval trials that are suboptimal for informing prescribers but more likely than optimal designs to yield favorable results.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Antidepressant medications and their association with invasive breast cancer and carcinoma in situ of the breast

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Estimation of apoptosis in C6 glioma cells treated with antidepressants.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Cancer recurrences and secondary primary cancers after use of antihistamines or antidepressants

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Inhibition of apoptosis as a mechanism of tumor promotion

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

Preclinical toxicology of bupropion: an overview.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071810

SSRI use and breast cancer risk by hormone receptor status

27 November 2018

1 reference

12 December 2020

Screening for breast cancer: recommendations and rationale

1 reference

12 December 2020

Antidepressant medication use and breast cancer risk

1 reference

12 December 2020

Risk of ovarian cancer according to use of antidepressants, phenothiazines, and benzodiazepines (United States)

1 reference

12 December 2020

Antidepressant use and the risk of breast cancer: a non-association

1 reference

12 December 2020

Synthetic and naturally occurring hydrazines as possible cancer causative agents

1 reference

12 December 2020

A comparison of cell proliferation in normal and neoplastic intestinal epithelia following either biogenic amine depletion or monoamine oxidase inhibition

1 reference

12 December 2020

Nonestrogenic drugs and breast cancer

1 reference

12 December 2020

Potentiation of chemotherapeutic effect of vincristine in vincristine resistant tumor bearing mice by calmodulin inhibitor clomipramine

1 reference

12 December 2020

Growth-inhibitory effects of serotonin uptake inhibitors on human prostate carcinoma cell lines

1 reference

12 December 2020

Conflict of interest in the debate over calcium-channel antagonists

1 reference

12 December 2020

Psychotropic medication use and risk of epithelial ovarian cancer

1 reference

12 December 2020

Breast cancer risk among users of antidepressant medications

1 reference

12 December 2020

Antidepressant medication use [corrected] and risk of ovarian cancer

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0018210

Identifiers

DOI

1 reference

ADS bibcode

2011PLoSO...618210C

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1 reference

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21494667

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