(Q28478114)

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Hypochlorous acid-induced heme degradation from lactoperoxidase as a novel mechanism of free iron release and tissue injury in inflammatory diseases

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Hypochlorous acid-induced heme degradation from lactoperoxidase as a novel mechanism of free iron release and tissue injury in inflammatory diseases (English)

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object named as

Dhiman Maitra

2

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Michael P. Diamond

object named as

Michael P Diamond

4

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author name string

Carlos Eduardo A Souza

1

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Ghassan M Saed

3

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Arlindo A Moura

5

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Subramaniam Pennathur

6

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Husam M Abu-Soud

7

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publication date

2011

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6

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11

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e27641

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Creative Commons Attribution 4.0 International

22 November 2011

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April 2022 Public Data File from Crossref

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describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3222650/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

First structural evidence for the mode of diffusion of aromatic ligands and ligand-induced closure of the hydrophobic channel in heme peroxidases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

19 March 2017

The lactoperoxidase system links anion transport to host defense in cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

19 March 2017

A novel host defense system of airways is defective in cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

19 March 2017

Lactoperoxidase and human airway host defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

19 March 2017

Lactoperoxidase and hydrogen peroxide metabolism in the airway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

19 March 2017

X-ray crystal structure and characterization of halide-binding sites of human myeloperoxidase at 1.8 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

19 March 2017

Chlorination of taurine by human neutrophils. Evidence for hypochlorous acid generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

19 March 2017

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

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19 March 2017

Anti-sickling effect of dietary thiocyanate in prophylactic control of sickle cell anemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

19 March 2017

Nitric oxide is a physiological substrate for mammalian peroxidases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

19 March 2017

Myeloperoxidase: friend and foe

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

7 April 2017

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

7 April 2017

Reaction of hemoglobin with HOCl: mechanism of heme destruction and free iron release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Mechanism of hypochlorous acid-mediated heme destruction and free iron release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

The protein cargo of HDL: implications for vascular wall biology and therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Hypertonic saline increases lung epithelial lining fluid glutathione and thiocyanate: two protective CFTR-dependent thiols against oxidative injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Potent antioxidative activity of lycopene: A potential role in scavenging hypochlorous acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Myeloperoxidase interaction with peroxynitrite: chloride deficiency and heme depletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Role of antioxidant activity of taurine in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Potential involvement of iron in the pathogenesis of peritoneal endometriosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Mammalian heme peroxidases: from molecular mechanisms to health implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Hypochlorous acid as a potential wound care agent: part I. Stabilized hypochlorous acid: a component of the inorganic armamentarium of innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Is taurine a functional nutrient?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Origin, structure, and biological activities of peroxidases in human saliva

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Free heme toxicity and its detoxification systems in human

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Heme degradation by reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Kinetics of interconversion of redox intermediates of lactoperoxidase, eosinophil peroxidase and myeloperoxidase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

High dissociation rate constant of ferrous-dioxy complex linked to the catalase-like activity in lactoperoxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Iron, atherosclerosis, and neurodegeneration: a key role for cholesterol in promoting iron-dependent oxidative damage?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Inflammatory and oxidative markers in atherosclerosis: relationship to outcome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Myeloperoxidase in kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Chemical basis of inflammation-induced carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Emerging role of myeloperoxidase and oxidant stress markers in cardiovascular risk assessment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Protein aggregation in disease: a role for folding intermediates forming specific multimeric interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Molecular and cellular mechanisms of iron homeostasis and toxicity in mammalian cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Molecular pathogenesis of iron overload.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Living with a killer: the effects of hypochlorous acid on mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Iron and atherosclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Myeloperoxidase and protein oxidation in cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Myeloperoxidase-generated oxidants and atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Amyloid diseases: abnormal protein aggregation in neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Current concepts: immunology. Neutrophils in human diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Tissue destruction by neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Molecular cloning of cDNAs encoding bovine and human lactoperoxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Targeting of proteins into the peroxisomal matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

29 September 2017

Characterization of non-covalent oligomers of proteins treated with hypochlorous acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

2 June 2018

Reactive oxygen-mediated protein oxidation in aging and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

2 June 2018

Analysis of the peptide subunits of human neutrophil myeloperoxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

2 June 2018

Action of hypochlorous acid on the antioxidant protective enzymes superoxide dismutase, catalase and glutathione peroxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

2 June 2018

Accumulation of Hypothiocyanite Ion during Peroxidase-Catalyzed Oxidation of Thiocyanate Ion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

2 June 2018

Identifying peroxidases and their oxidants in the early pathology of cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

27 November 2018

Sputum Trace Metals Are Biomarkers of Inflammatory and Suppurative Lung Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

27 November 2018

What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

27 November 2018

Oxidative stress and "senescent" fibroblasts in non-healing wounds as potential therapeutic targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

27 November 2018

Cystic fibrosis: ironing out the problem of infection?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

27 November 2018

Contents of endometriotic cysts, especially the high concentration of free iron, are a possible cause of carcinogenesis in the cysts through the iron-induced persistent oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

27 November 2018

Iron, nitric oxide, and myeloperoxidase in asthmatic patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

27 November 2018

Hydrogen peroxide-scavenging properties of normal human airway secretions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

27 November 2018

The lactoperoxidase system functions in bacterial clearance of airways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

27 November 2018

Dityrosine, a specific marker of oxidation, is synthesized by the myeloperoxidase-hydrogen peroxide system of human neutrophils and macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222650

27 November 2018

Redox buffering of hypochlorous acid by thiocyanate in physiologic fluids

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of Chlorine Dioxide and Chlorate Ion Formation from the Reaction of Hypobromous Acid and Chlorite Ion

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assays for the chlorination activity of myeloperoxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Some properties of human eosinophil peroxidase, a comparison with other peroxidases

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salivary lysozyme, lactoferrin and peroxidases: antibacterial effects on cariogenic bacteria and clinical applications in preventive dentistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidation of thiocyanate to cyanide and sulfate by the lactoperoxidase-hydrogen peroxide system

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel multistep mechanism for oxygen binding to ferrous hemoproteins: rapid kinetic analysis of ferrous-dioxy myeloperoxidase (compound III) formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic studies on the reaction of compound II of myeloperoxidase with ascorbic acid. Role of ascorbic acid in myeloperoxidase function

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiocyanate modulates the catalytic activity of mammalian peroxidases

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Standard reduction potentials of all couples of the peroxidase cycle of lactoperoxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical evidence for the myeloperoxidase/H2O2/halide system in human atherosclerotic lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Airway iron and iron-regulatory cytokines in cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reaction of ferrous lactoperoxidase with hydrogen peroxide and dioxygen: an anaerobic stopped-flow study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of peroxidase on the enzymatic and candidacidal activities of lysozyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactions of superoxide with myeloperoxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myeloperoxidase metabolizes thiocyanate in a reaction driven by nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reaction of Lactoperoxidase Compound I with Halides and Thiocyanate†

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low catalytic turnover of horseradish peroxidase in thiocyanate oxidation. Evidence for concurrent inactivation by cyanide generated through one-electron oxidation of thiocyanate

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxidases inhibit nitric oxide (NO) dependent bronchodilation: development of a model describing NO-peroxidase interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spectrophotometric determination of serum iron at the submicrogram level with a new reagent (ferrozine)

1 reference

https://pubmed.ncbi.nlm.nih.gov/22132121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0027641

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2011PLoSO...627641S

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